Opendata, web and dolomites

DRmov SIGNED

Deciphering the RBPome in mosquitoes during virus infection

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 DRmov project word cloud

Explore the words cloud of the DRmov project. It provides you a very rough idea of what is the project "DRmov" about.

roles    cellular    encephalitic    habitats    binding    despite    transmitting    veev    therapies    dynamics    interests    dramatically    insect    vectors    global    replication    zikv    yfv    genes    broad    diseases    persistence    rna    modified    venezuelan    vulnerabilities    chikungunya    metabolism    mosquitoes    decades    natural    invertebrate    resistance    capture    players    responsible    borne    turning    envision    comprehensively    emerge    fever    re    aedes    last    vector    risk    billion    advisory    usually    virus    insecticides    potentially    performed    disease    yellow    scientists    world    exhibit    edge    dengue    zika    inserted    cutting    compendium    organisation    health    treatment    deaths    antiviral    genome    million    disrupted    viruses    ideal    poorly    chkv    invasive    play    ic    spread    host    genetically    rbps    infections    mosquito    equine    expanded    denv    toward    viral    group    infection    profile    interactome    populations    countries    few    rnai    spectrum    rbpome    pathogens    efficacy    virologists    urged    proteins   

Project "DRmov" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD 

Organization address
address: WELLINGTON SQUARE UNIVERSITY OFFICES
city: OXFORD
postcode: OX1 2JD
website: www.ox.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 224˙933 €
 EC max contribution 224˙933 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) coordinator 224˙933.00

Map

 Project objective

The impact of mosquito-borne diseases has expanded dramatically in the last few decades to become an emerging global health problem, with around 1 billion new infections and 1 million deaths each year. In Europe there are more than 20 countries with established populations of invasive Aedes mosquitoes. Aedes mosquitoes are the principle vectors responsible for transmitting high-risk pathogens such as ZIKA virus (ZIKV), dengue (DENV), yellow fever virus (YFV), chikungunya virus (CHKV) and Venezuelan equine encephalitic virus (VEEV). Despite our vulnerabilities to mosquito-borne diseases, virus replication dynamics is still poorly understood especially in the invertebrate vectors. No treatment against these viruses targeting essential viral proteins are currently available. Thus, the World Health Organisation (WHO) and its Vector Control Advisory Group has urged for insect vector control. Vector control is usually performed through insecticides; however, resistance can emerge in mosquitoes leading to persistence of the disease. Therefore, virologists are turning their interests toward host factors that play essential roles in infection as novel antiviral targets, since they can potentially exhibit broad-spectrum efficacy. In particular, scientists envision that genetically modified mosquitoes with disrupted genes required for infection can be re-inserted into natural habitats or through targeting these genes by RNAi in order to control viral spread. As all mosquito-borne viruses have RNA genome, cellular RNA-binding proteins (RBPs) emerge as ideal targets for antiviral therapies, as they are key players in cellular and viral RNA metabolism . Thus, we propose here to profile comprehensively the compendium of mosquito RBPs (RBPome) using RNA-interactome capture (RNA-IC). Furthermore, we will apply different cutting-edge methods to identify the role of mosquito RBPs during virus infection.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "DRMOV" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "DRMOV" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

MingleIFT (2020)

Multi-color and single-molecule fluorescence imaging of intraflagellar transport in the phasmid chemosensory cilia of C. Elegans

Read More  

PNAIC (2018)

Positive and Negative Asymmetry in Intergroup Contact: Its Impact on Linguistic Forms of Communication and Physiological Responses

Read More  

POMOC (2019)

Charles IV and the power of marvellous objects

Read More