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Capsule based machines for the automated synthesis of organic molecules for drug discovery and medicinal chemistry

Total Cost €


EC-Contrib. €






 AutoCapSyn project word cloud

Explore the words cloud of the AutoCapSyn project. It provides you a very rough idea of what is the project "AutoCapSyn" about.

drug    chemical    supply    successful    size    lower    simplify    exploration    time    toxic    delays    appropriate    ing    prepare    synthesises    unpredictable    chain    structure    touch    first    completion    timesaving    unfriendly    gaining    exposure    flexibility    amounts    dynamics    capsules    introduces    consuming    market    aid    safe    reaction    purification    technically    ultimately    tiny    environmentally    machine    rely    expensive    feasibility    components    environment    data    feasible    deeper    countries    synthesis    benefits    efficient    commercially    capsule    flow    minus    compatibility    agents    protocols    unsafe    critical    route    enclosed    form    discovery    specialists    declining    leader    molecules    continues    amount    launch    marketing    offers    robustness    frequency    automated    safety    synple    button    optimal    productivity    goals    machines    biological    innovative    pricing    candidate    sales    channels    commercial    safer    minimised    benchtop    scaffolds    trained    customer   

Project "AutoCapSyn" data sheet

The following table provides information about the project.


Organization address
city: ZURICH
postcode: 8093
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-10-01   to  2020-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SYNPLE CHEM AG CH (ZURICH) coordinator 50˙000.00


 Project objective

Drug discovery continues to rely on the synthesis of tiny amounts of candidate molecules using unpredictable protocols that require highly trained specialists. As such, it remains expensive, time-consuming, unsafe, and environmentally unfriendly. Declining productivity, high costs, and safety issues, have driven a large amount of chemical synthesis to lower cost countries, which introduces delays and uncertainty in the drug discovery process, where the flexibility to rapidly prepare new molecules in response to biological data is critical to success.

In order to address these problems, Synple has developed an innovative, benchtop, capsule-based machine that synthesises new molecules at the touch of a button. This fully automated technology offers significant timesaving and productivity benefits. With all necessary components for the safe execution of the reaction and purification of the resulting products enclosed within the capsule, the user’s exposure to toxic agents will be minimised. Use of the automated machines with the innovative capsules will aid chemical research organisations as they can greatly simplify the way in which key chemical scaffolds are produced while providing a safer and more efficient work environment.

The first goal of this feasibility study is to determine if the technology is technically feasible in its current form (robustness and compatibility with customer’s current work flow). The second goal – exploration of the commercially feasibility − will be achieved by gaining a deeper insight in the market size and dynamics, as well as determining frequency of use. Upon successful completion of these goals, we aim to then establish the steps required for commercial launch. Key parameters include: defining the supply chain and pricing structure and identifying the most appropriate sales, marketing and distribution channels. Ultimately, Synple aims to use this feasibility study to identify the optimal route to becoming the market leader.

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The information about "AUTOCAPSYN" are provided by the European Opendata Portal: CORDIS opendata.

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