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QUALITOP SIGNED

Monitoring multidimensional aspects of QUAlity of Life after cancer ImmunoTherapy - an Open smart digital Platform for personalized prevention and patient management

Total Cost €

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EC-Contrib. €

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Partnership

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Project "QUALITOP" data sheet

The following table provides information about the project.

Coordinator
HOSPICES CIVILS DE LYON 

Organization address
address: QUAI DES CELESTINS 3
city: LYON
postcode: 69002
website: www.chu-lyon.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 5˙196˙772 €
 EC max contribution 5˙196˙772 € (100%)
 Programme 1. H2020-EU.3.1.5.1. (Improving halth information and better use of health data)
2. H2020-EU.3.1.3.2. (Transferring knowledge to clinical practice and scalable innovation actions)
 Code Call H2020-SC1-DTH-2019
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2023-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HOSPICES CIVILS DE LYON FR (LYON) coordinator 889˙375.00
2    LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER UK (LONDON) participant 567˙395.00
3    SCIENTIFIC ACADEMY FOR SERVICE TECHNOLOGY EV DE (POSTDAM) participant 496˙625.00
4    THE GENERAL HOSPITAL CORPORATION US (BOSTON MA) participant 457˙966.00
5    UNIVERSITE LYON 1 CLAUDE BERNARD FR (VILLEURBANNE CEDEX) participant 406˙125.00
6    ACADEMISCH ZIEKENHUIS GRONINGEN NL (GRONINGEN) participant 356˙750.00
7    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) participant 356˙557.00
8    CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER ES (BARCELONA) participant 354˙972.00
9    UNIVERSITE LUMIERE LYON 2 FR (LYON) participant 352˙681.00
10    UNIVERSITA DELLA CALABRIA IT (ARCAVACATA DI RENDE) participant 278˙500.00
11    EUROPEAN CANCER PATIENT COALITION BE (BRUXELLES) participant 272˙625.00
12    INSTITUTO PORTUGUES DE ONCOLOGIA DE LISBOA FRANCISCO GENTIL EPE PT (LISBOA) participant 184˙325.00
13    LYON INGENIERIE PROJETS FR (VILLEURBANNE) participant 151˙250.00
14    CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE BESANCON FR (BESANCON CEDEX) participant 71˙625.00

Map

 Project objective

'Cancer immunotherapy brought about significant progress in cancer treatment. It resulted in high efficacy in some cancers; e.g., up to 60% objective response rate in melanoma and 80% complete response rate in acute lymphoblastic leukaemia. Nevertheless, two main challenges still impede improving cancer patients’ health status and quality of life (QoL) after immunotherapy initiation: 1) a crucial need for “predictive markers” of occurrence of immunotherapy-related adverse events (IR-AEs) to predict and improve patients’ health status and promote their QoL; and, 2) the lack of knowledge on patients after start of immunotherapy outside randomised controlled trials. To reach these goals, significantly more diversified sources of data are required. Project QUALITOP aims at developing a European immunotherapy-specific open Smart Digital Platform and using big data analysis, artificial intelligence, and simulation modelling approaches. This will enable collecting and aggregating efficiently real-world data to monitor health status and QoL of cancer patients given immunotherapy. Through causal inference analyses, QUALITOP will identify the determinants of health status regarding IR-AEs and define patient profiles in a real-world context. For this, heterogeneous data sources (big data), both retrospective and prospective --collected for QUALITOP from clinical centres in four EU countries—will integrate lifestyle, genetic, and psychosocial determinants of QoL. Using machine learning approaches, QUALITOP will provide 'real-time' recommendations stemming from patient profiles and feedbacks via the Smart Digital Platform. Furthermore, an increased visibility on patients’ behaviour, a better IR-AEs prediction, and an improvement of care coordination will help analysing through simulation modelling approaches the gain in cost-effectiveness. Guidelines will be issued over the short and long-term. '

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The information about "QUALITOP" are provided by the European Opendata Portal: CORDIS opendata.

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