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mfloDx SIGNED

Adaptable Multiflow Diagnostic Platform to Genetically Identify Drug Resistant Infection

Total Cost €

0

EC-Contrib. €

0

Partnership

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 mfloDx project word cloud

Explore the words cloud of the mfloDx project. It provides you a very rough idea of what is the project "mfloDx" about.

antibiotic    killed    suffering    costly    projected    tests    point    flourishing    people    treatments    stop    diagnostic    bacteria    accurate    appropriate    pilot    hours    alarming    recommended    100    euros    market    resistant    prescription    six    organization    drug    prescriptions    frac14    tbplus    2030    patient    afflicted    efficiency    life    mdr    times    identification    33    regimens    spreading    96    unnecessary    diagnosis    time    2024    incomplete    world    patients    curtail    rapid    treatment    billion    forms    health    commercial    close    recommend    thereby    lag    tuberculosis    population    2000    molecular    tens    countries    reduce    care    strains    million    mid    showed    antibiotics    detection    infections    infects    estimates    minimdr    urgently    spread    rate    diagnoses    worldwide    platform    faulty    months    incorrect    undergo    tb    expenditure    32k    983    thousands    inappropriate    first    grow    income    trained    suggest    power    tools    92    untreatable    2015    specificity    global    mflodx    addressable    diagnostics    prevent    treat    generation    15   

Project "mfloDx" data sheet

The following table provides information about the project.

Coordinator		 EMPE DIAGNOSTICS AB 

Organization address
address: KAROLINSKA ISTITUTE SCIENCE PARK NOBELS VAG 16
city: STOCKHOLM
postcode: 171 65
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Sweden [SE]
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-12-01   to  2020-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EMPE DIAGNOSTICS AB SE (STOCKHOLM) coordinator 50˙000.00

Map

 Project objective

Tuberculosis (TB) killed 33 million people worldwide in 2000-2015 and infects an estimated ¼ of the world population. Drug-resistant forms of TB are flourishing at an alarming rate due to faulty diagnosis and widespread prescription of incorrect antibiotics. Rapid and accurate detection of multi-drug resistant (MDR) strains is urgently needed to effectively treat patients and prevent spreading of untreatable TB forms. Simple, low cost diagnostic tools are needed to enable point-of-care testing in low- and mid-income countries. mfloDx is a low-cost, simple diagnostic platform that can identify close to 100% of drug resistant TB cases. Pilot tests of the first product, miniMDR-TB, showed the efficiency and specificity to be 92-96% in agreement with that of another molecular test recommended by the World Health Organization. Our next-generation mfloDx products, MDR-TB and MDR-TBplus, are expected to have close to 100% MDR-TB identification power. The low cost of mfloDx tests will enable market uptake in highly afflicted developing countries, and thereby help to stop the loss of life, the spread of antibiotic-resistant infections, and prevent unnecessary costs. Projected global expenditure on diagnosis and treatment of TB will reach €983 billion between 2015-2030. The addressable market for TB diagnostics is projected to grow to €3.1 billion by 2024. Available commercial diagnostics for MDR-TB often deliver incomplete diagnoses and require long lag times, costly equipment (€15-32K), and highly trained personnel to recommend prescriptions. As a result, less than one-third of new TB patients undergo testing to determine appropriate antibiotic treatments. Our estimates suggest that mfloDx would reduce the treatment costs per MDR-TB patient by tens of thousands of euros and diagnosis time from about six months to two hours. This would avoid costly and inappropriate antibiotic regimens, reduce patient suffering, and curtail the spread of drug-resistant bacteria.

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The information about "MFLODX" are provided by the European Opendata Portal: CORDIS opendata.

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