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POLYBOOST

POLYBOOST: Renovating the Polyclonal Immunotherapy

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

POLYBOOST project word cloud

Explore the words cloud of the POLYBOOST project. It provides you a very rough idea of what is the project "POLYBOOST" about.

damaged believe transplantation entering days waited market medical prevent demand driving europeans transplanted population move 41 customized fight full perspectives influencing time organ effect diseases autoimmune revenues severe safe immune 352 retain views waiting death rejection incidence stimuli rising people created stimulate cancer survival significantly financial successful huge avantea polyboost society induce antigenicity risk platform administered list organs reducing turn revolutionize doses hiring immunotherapy immunological benefits progressive suppress polyclonal medicine safer achievement scarce patients immunosuppressants life commercial surgery severely disrupt polyclonals efficiency plan ageing proven registering chronic xenothera innovative clinicians customizing

Project "POLYBOOST" data sheet

The following table provides information about the project.

Coordinator	XENOTHERA Organization address address: FACUKTE DE MEDECINE, 1 RUE GASTON VEIL city: NANTES postcode: 44035 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Project website	http://www.xenothera.com/
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.3.1.3. (Treating and managing disease)
Code Call	H2020-SMEINST-1-2016-2017
Funding Scheme	SME-1
Starting year	2016
Duration (year-month-day)	from 2016-12-01 to 2017-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	XENOTHERA XENOTHERA Organization address address: FACUKTE DE MEDECINE, 1 RUE GASTON VEIL city: NANTES postcode: 44035 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (NANTES)	coordinator	50˙000.00
2	AVANTEA srl AVANTEA srl Organization address address: via Cabrini 12 city: Cremona postcode: 26100 website: www.avantea.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (Cremona)	participant	0.00

Map

Project objective

Immunotherapy is an essential field of medicine that allows clinicians to stimulate or to suppress the response of our immune system against specific stimuli. The progressive ageing of the population and the rising incidence of chronic diseases is driving the demand for immunotherapy, as it can be used to fight cancer or autoimmune diseases. One of its major applications today is to prevent the rejection of transplanted organs. Since organs are scarce (40,000 Europeans on waiting list), patients are administered high doses of polyclonal immunosuppressants for several days around the time of surgery to prevent rejection. However, current polyclonals are not safe or reliable. Patients respond to these products by developing severe side effects that increase the risk for death & the medical costs. Thus, current polyclonals are only open for one time use. Also, the transplanted organ is severely damaged in the process, reducing its life-survival. In response, the consortium XENOTHERA & AVANTEA has created this project with the main objective of bringing to market a unique platform for the production of safer polyclonals (POLYBOOST). Our innovative method will revolutionize the field of immunotherapy, since it enables production of customized polyclonal products of low antigenicity, which retain a full immunological effect but do not induce side effects. We have proven the efficiency of POLYBOOST by customizing a polyclonal for transplantation medicine. In views of this successful achievement, we now aim to move forward towards the market. Thus, in Phase 1 we plan to assess all the aspects influencing the project from the technical, commercial and financial perspectives. We believe POLYBOOST will bring huge benefits for society and medicine, entering the market with a so long waited for product that will disrupt transplantation medicine. In turn, we expect the project to impact our growth significantly, registering €352 M in revenues and hiring 41 new people in 5 years.

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The information about "POLYBOOST" are provided by the European Opendata Portal: CORDIS opendata.

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