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ORIGIN SIGNED

Optical Fibre Dose Imaging for Adaptive Brachytherapy

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "ORIGIN" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF LIMERICK 

Organization address
address: NATIONAL TECHNOLOGICAL PARK, PLASSEY
city: LIMERICK
postcode: -
website: www.ul.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Total cost 4˙819˙920 €
 EC max contribution 4˙819˙920 € (100%)
 Programme 1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
 Code Call H2020-ICT-2019-2
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2022-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF LIMERICK IE (LIMERICK) coordinator 913˙380.00
2    VRIJE UNIVERSITEIT BRUSSEL BE (BRUSSEL) participant 741˙528.00
3    DOSEVUE BE (Diepenbeek) participant 705˙250.00
4    THE QUEEN'S UNIVERSITY OF BELFAST UK (BELFAST) participant 688˙342.00
5    ECKERT & ZIEGLER BEBIG GMBH DE (BERLIN) participant 590˙812.00
6    UNIVERSITA DEGLI STUDI DELL'INSUBRIA IT (VARESE) participant 462˙150.00
7    GALWAY CLINIC DOUGHISKA LIMITED IE (GALWAY) participant 372˙456.00
8    CENTRE ANTOINE LACASSAGNE FR (NICE CEDEX) participant 346˙000.00

Map

 Project objective

ORIGIN aims to deliver more effective, photonics-enabled, brachytherapy for cancer treatment through advanced real-time radiation dose imaging and source localisation. This will be achieved by the development of a new optical fibre based sensor system to support diagnostics-driven therapy through enhanced adaptive brachytherapy. A 16-point optical fibre sensors system will be developed, for Low Dose Rate (LDR) and High Dose Rate (HDR) Brachytherapy, with sensitivity of 150 counts/Gy for LDR- and 2500 counts/mGy for HDR- BT alongside a dedicated data acquisition system providing a dose mapping system with a spatial resolution of 0.5mm (HDR) and 3mm (LDR) and time resolution of 0.1s (HDR) and 0.5s (LDR), with 5% uncertainty. This is a 50% improvement in uncertainty over existing systems. Further interrogation of the optical signal will provide real-time monitoring of the radiation source location during treatment. The ORIGIN system will be integrated into existing clinical brachytherapy treatment planning and delivery systems to confirm that the dose prescribed to the tumour is achieved, whilst ensuring the dose to organs at risk (OARs) is within acceptable limits. This will provide for optimised dose-led, patient-oriented, personalised treatment plans leading to improved patient outcomes and prevention of treatment errors, with the potential to reduce the overall risk of treatment error by 55%. The optical fibre radiation dosimeters will be further optimised for improved optical signal collection efficiency, higher signal-to-noise ratio (SNR) and repeatable high volume fabrication. Taking manufacturability into consideration from the outset will ensure that ORIGIN establishes Europe at the fore of brachytherapy system development and photonics manufacturing.

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The information about "ORIGIN" are provided by the European Opendata Portal: CORDIS opendata.

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