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Fast optoacoustic mesoscopy, using the skin as a window for therapeutic monitoring of local and systemic disease.

Total Cost €


EC-Contrib. €






 WINTHER project word cloud

Explore the words cloud of the WINTHER project. It provides you a very rough idea of what is the project "WINTHER" about.

cardio    conventional    diagnostic    2016    progression    photoacoustic    disease    generation    pathophysiological    innoderm    endothelial    bio    5mm    improves    algorithms    paradigm    function    winther    monitoring    invisible    therapeutic    oxygenation    aided    deep    orders    modern    history    accuracy    clinical    morphological    optic    imaging    magnitude    shown    fuelled    depths    diagnostics    diabetes    macroscopy    skin    mesoscopy    mesoscopic    window    dermatology    computation    inflammatory    therapy    optoacoustics    tum    scan    commercialised    apparent    experts    parallel    rayfos    artificial    optical    framework    sonaxis    builds    metabolic    dramatically    diseases    ithera    medical    tissues    rsom    faster    inside    prof    medicine    fast    termed    resolution    mm    2008    deterministic    leadership    ntziachristos    personalized    ict    components    physicians    cardiovascular    dimensional    data    intelligence    photonics    hunimed    shift    commercializing    cm    previously    image    awards    placed    raster    erc    optoacoustic    barriers    globally   

Project "WINTHER" data sheet

The following table provides information about the project.


Organization address
address: Arcisstrasse 21
postcode: 80333

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 5˙111˙203 €
 EC max contribution 4˙292˙170 € (84%)
 Programme 1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
 Code Call H2020-ICT-2019-2
 Funding Scheme IA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2024-12-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
2    ITHERA MEDICAL GMBH DE (MUNCHEN) participant 946˙837.00
3    HUMANITAS UNIVERSITY IT (PIEVE EMANUELE) participant 860˙000.00
4    RAYFOS LTD UK (BASINGSTOKE) participant 493˙500.00
5    SONAXIS SA FR (BESANCON) participant 470˙741.00


 Project objective

Optoacoustic (photoacoustic) imaging dramatically improves upon conventional bio-optic barriers and enables three-dimensional, high-resolution optical imaging deep inside tissues (several mm to cm). Clinical optoacoustic macroscopy has been supported by two ERC Advanced Awards (2008, 2016; Prof. Ntziachristos). In parallel, under the ICT program INNODERM, we developed mesoscopic optoacoustic imaging for dermatology diagnostics. Termed raster-scan optoacoustic mesoscopy (RSOM), the method can image previously invisible ❶ pathophysiological/oxygenation and ❷ morphological features of the skin at depths of 1-5mm. RSOM has already shown clinical diagnostic value in dermatology and, fuelled by INNODERM, has been commercialised and globally placed by iThera Medical. WINTHER builds on this success. While INNODERM focused on diagnostic dermatology, it has become apparent that RSOM can also assess progression and therapy not only in skin but also in cardiovascular diseases and diabetes. However, to achieve this, RSOM should be able to assess endothelial function, ability that it is not yet available. WINTHER will build next-generation fast RSOM (F-RSOM), operating up to two orders of magnitude faster than state-of-the-art RSOM, enabling it to assess not only ❶,❷ above but also ❸ endothelial function. Using the skin as a window for disease assessment and aided by a modern computation framework, based on deterministic and artificial intelligence algorithms, F-RSOM aims to improve the clinical accuracy of RSOM and shift the paradigm in therapeutic monitoring of cardio-metabolic diseases and inflammatory skin conditions, strengthening Europe's leadership in photonics and in personalized medicine. The project is driven iThera Medical with a strong history of commercializing optoacoustics for clinical applications, by leading physicians (TUM, HUNIMED), and by RSOM, RSOM components and data analysis experts (TUM, iThera, Rayfos, Sonaxis).

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The information about "WINTHER" are provided by the European Opendata Portal: CORDIS opendata.

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