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CISBOOM SIGNED

Convergence of Information from Separate Brain Areas to Orchestrate Orienting Movements

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 CISBOOM project word cloud

Explore the words cloud of the CISBOOM project. It provides you a very rough idea of what is the project "CISBOOM" about.

segregated    seem    animal    varies    inputs    restricted    afferent    coordinates    midbrain    attentional    stimuli    movements    receive    percept    precise    calcium    recruits    interact    filtered    separate    modalities    structure    binding    viruses    sites    evolution    functional    forms    bind    content    anatomical    guide    locate    area    colliculus    label    examine    converging    employ    move    hypothesis    photon    induce    monosynaptically    question    coherent    environment    reveal    attempt    brain    fundamental    first    superior    poised    tuning    conserved    oriented    presynaptic    animals    rotations    trigger    subpopulation    handling    elicit    inside    motor    positions    patches    alone    merged    execute    representation    engages    receptive    potentially    trans    orienting    record    perception    neurons    distinctive    unified    sensory    cortical    movement    multiple    locations    recipient    create    diversity    combined    head    subcortical    awake    neuronal    imaging    space    convey    objects    mice    probe    ancient    synaptic   

Project "CISBOOM" data sheet

The following table provides information about the project.

Coordinator
UNITED KINGDOM RESEARCH AND INNOVATION 

Organization address
address: POLARIS HOUSE NORTH STAR AVENUE
city: SWINDON
postcode: SN2 1FL
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 224˙933 €
 EC max contribution 224˙933 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2021
 Duration (year-month-day) from 2021-01-01   to  2022-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNITED KINGDOM RESEARCH AND INNOVATION UK (SWINDON) coordinator 224˙933.00

Map

 Project objective

To interact with our environment, we identify, locate and move towards objects of interest. This recruits multiple brain areas, handling separate aspects. Indeed, perception alone engages several cortical and subcortical areas, processing specific features or sensory modalities. How this information is then merged to create a unified percept is a fundamental question, known as the binding problem. Here, we address this question by studying the superior colliculus, a midbrain area essential for orienting. Inside this structure, a neuronal subpopulation forms segregated patches, which elicit precise head rotations, and receive sensory-, motor- and attentional-related inputs. These anatomical sites seem well poised to bring together information from similar locations or objects, to induce orienting towards them. To test this hypothesis, I will probe how coherent these converging inputs are, in terms of feature tuning and receptive field coordinates. To investigate if inputs convey filtered information, I will assess the functional diversity of afferent neurons in each brain area. I will then examine whether this content varies across recipient patches, to determine whether stimuli at distinctive positions trigger head rotations. To label and record presynaptic partners, I will employ monosynaptically restricted trans-synaptic viruses, combined with two photon calcium imaging in awake mice. This project will reveal how animals create a representation of space in order to execute target-oriented movements. Because the superior colliculus is an ancient and conserved structure, this is potentially evolution’s first attempt to bind coherent processes to guide movement, animal’s main concern.

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The information about "CISBOOM" are provided by the European Opendata Portal: CORDIS opendata.

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