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CISBOOM SIGNED

Convergence of Information from Separate Brain Areas to Orchestrate Orienting Movements

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 CISBOOM project word cloud

Explore the words cloud of the CISBOOM project. It provides you a very rough idea of what is the project "CISBOOM" about.

diversity    potentially    recipient    colliculus    viruses    varies    orienting    move    oriented    mice    awake    elicit    guide    question    binding    head    motor    label    multiple    percept    midbrain    coordinates    first    animal    combined    coherent    handling    recruits    examine    bind    distinctive    precise    segregated    employ    representation    inside    space    trigger    converging    alone    brain    synaptic    anatomical    imaging    engages    stimuli    record    movement    content    attempt    probe    cortical    conserved    create    animals    environment    superior    sensory    subpopulation    execute    attentional    fundamental    seem    evolution    locate    structure    filtered    tuning    afferent    merged    perception    induce    modalities    unified    interact    sites    separate    calcium    photon    inputs    reveal    monosynaptically    poised    rotations    hypothesis    locations    neuronal    functional    objects    presynaptic    trans    ancient    subcortical    area    forms    receptive    convey    restricted    positions    movements    receive    patches    neurons   

Project "CISBOOM" data sheet

The following table provides information about the project.

Coordinator
UNITED KINGDOM RESEARCH AND INNOVATION 

Organization address
address: POLARIS HOUSE NORTH STAR AVENUE
city: SWINDON
postcode: SN2 1FL
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 224˙933 €
 EC max contribution 224˙933 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2021
 Duration (year-month-day) from 2021-01-01   to  2022-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNITED KINGDOM RESEARCH AND INNOVATION UK (SWINDON) coordinator 224˙933.00

Map

 Project objective

To interact with our environment, we identify, locate and move towards objects of interest. This recruits multiple brain areas, handling separate aspects. Indeed, perception alone engages several cortical and subcortical areas, processing specific features or sensory modalities. How this information is then merged to create a unified percept is a fundamental question, known as the binding problem. Here, we address this question by studying the superior colliculus, a midbrain area essential for orienting. Inside this structure, a neuronal subpopulation forms segregated patches, which elicit precise head rotations, and receive sensory-, motor- and attentional-related inputs. These anatomical sites seem well poised to bring together information from similar locations or objects, to induce orienting towards them. To test this hypothesis, I will probe how coherent these converging inputs are, in terms of feature tuning and receptive field coordinates. To investigate if inputs convey filtered information, I will assess the functional diversity of afferent neurons in each brain area. I will then examine whether this content varies across recipient patches, to determine whether stimuli at distinctive positions trigger head rotations. To label and record presynaptic partners, I will employ monosynaptically restricted trans-synaptic viruses, combined with two photon calcium imaging in awake mice. This project will reveal how animals create a representation of space in order to execute target-oriented movements. Because the superior colliculus is an ancient and conserved structure, this is potentially evolution’s first attempt to bind coherent processes to guide movement, animal’s main concern.

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The information about "CISBOOM" are provided by the European Opendata Portal: CORDIS opendata.

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lastchecktime (2022-08-19 18:17:37) correctly updated