PRESSUREOSCILLATIONS

Pressure Oscillations: A New Lung Therapy Approach

 Coordinatore ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE 

 Organization address address: BATIMENT CE 3316 STATION 1
city: LAUSANNE
postcode: 1015

contact info
Titolo: Prof.
Nome: Nikolaos
Cognome: Stergiopulos
Email: send email
Telefono: +41 21 693 83 46
Fax: +41 21 693 96 35

 Nazionalità Coordinatore Switzerland [CH]
 Totale costo 128˙182 €
 EC contributo 128˙182 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2011-IIF
 Funding Scheme MC-IIF
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-09-01   -   2013-08-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

 Organization address address: BATIMENT CE 3316 STATION 1
city: LAUSANNE
postcode: 1015

contact info
Titolo: Prof.
Nome: Nikolaos
Cognome: Stergiopulos
Email: send email
Telefono: +41 21 693 83 46
Fax: +41 21 693 96 35

CH (LAUSANNE) coordinator 128˙182.10

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

cpap    airway    performance    flow    positive    oscillations    pressure    cerebral    blood   

 Obiettivo del progetto (Objective)

'The Continuous Positive Airway Pressure Device (CPAP) has been used as an effective way for the treatment of Obstructive Sleep Apnea. It provides air at positive pressure through a nasal or facial mask, creating a pneumatic splint that keeps the pharyngeal airway open during inspiration and expiration. However, many negative side effects have been reported including reduction in the cerebral blood flow (CBF). Pressure oscillations will be superimposed on the pressure signal produced by the CPAP to reduce its pressure requirement and eliminate some of the side effects. Airway pressure fluctuations stimulate the release of Adenosine Triphosphate (ATP) and may assist in relieving the collapsed airway associated with OSA by oscillating its compliant structure. Clinical trials will be conducted to assess the lung performance under pressure oscillations. Some of the side effects will be assessed, in particular the effect of the new technology on the cerebral blood flow. A computational dynamic model will be developed to assess the general performance characteristics of the new methodology. The new technology will be a platform for several other methodologies to treat respiratory ailments.'

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