4D-EEG

4D-EEG: A new tool to investigate the spatial and temporal activity patterns in the brain

Coordinatore	TECHNISCHE UNIVERSITEIT DELFT    more Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.
Nazionalità Coordinatore	Netherlands [NL]
Totale costo	3˙477˙201 €
EC contributo	3˙477˙201 €
Programma	FP7-IDEAS-ERC Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	ERC-2011-ADG_20110209
Funding Scheme	ERC-AG
Anno di inizio	2012
Periodo (anno-mese-giorno)	2012-06-01   -   2017-05-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG  Organization address address: De Boelelaan 1105 city: AMSTERDAM postcode: 1081 HV contact info Titolo: Dr. Nome: Erwin Cognome: Van Wegen Email: send email Telefono: +31 20 4440461	NL (AMSTERDAM)	beneficiary	1˙081˙148.40
2	STICHTING VU-VUMC  Organization address address: DE BOELELAAN 1105 city: AMSTERDAM postcode: 1081 HV contact info Nome: Michel Cognome: Telkamp Email: send email Telefono: +3120 444 8190	NL (AMSTERDAM)	beneficiary	0.00
3	TECHNISCHE UNIVERSITEIT DELFT  Organization address address: Stevinweg 1 city: DELFT postcode: 2628 CN contact info Titolo: Ms. Nome: Faizool Cognome: Jabbar Email: send email Telefono: +31 152788684	NL (DELFT)	hostInstitution	2˙396˙053.50
4	TECHNISCHE UNIVERSITEIT DELFT  Organization address address: Stevinweg 1 city: DELFT postcode: 2628 CN contact info Titolo: Prof. Nome: Franciscus C.T. Cognome: Van Der Helm Email: send email Telefono: +31 152785616 Fax: +31 152784717	NL (DELFT)	hostInstitution	2˙396˙053.50

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 Obiettivo del progetto (Objective)

'Our first goal is to develop a new tool to determine brain activity with a high temporal (< 1 msec) and spatial (about 2 mm) resolution with the focus on motor control. High density EEG (up to 256 electrodes) will be used for EEG source localization. Advanced force-controlled robot manipulators will be used to impose continuous force perturbations to the joints. Advanced closed-loop system identification algorithms will identify the dynamic EEG response of multiple brain areas to the perturbation, leading to a functional interpretation of EEG. The propagation of the signal in time and 3D space through the cortex can be monitored: 4D-EEG. Preliminary experiments with EEG localization have shown that the continuous force perturbations resulted in a better signal-to-noise ratio and coherence than the current method using transient perturbations.. 4D-EEG will be a direct measure of the neural activity in the brain with an excellent temporal response and easy to use in combination with motor control tasks. The new 4D-EEG method is expected to provide a breakthrough in comparison to functional MRI (fMRI) when elucidating the meaning of cortical map plasticity in motor learning. Our second goal is to generate and validate new hypotheses about the longitudinal relationship between motor learning and cortical map plasticity by clinically using 4D-EEG in an intensive, repeated measurement design in patients suffering from a stroke. The application of 4D-EEG combined with haptic robots will allow us to discover how dynamics in cortical map plasticity are related with upper limb recovery after stroke in terms of neural repair and using behavioral compensation strategies while performing a meaningful motor tasks.. The non-invasive 4D-EEG technique combined with haptic robots will open the window about what and how patients (re)learn when showing motor recovery after stroke in order to allow us to develop more effective patient-tailored therapies in neuro-rehabilitation.'