TIMCC

Tumor Infiltrating Myeloid Cell Compartment

 Coordinatore ACADEMISCH ZIEKENHUIS LEIDEN 

 Organization address address: Albinusdreef 2
city: LEIDEN
postcode: 2333 ZA

contact info
Titolo: Mr.
Nome: Ruud
Cognome: Esveld
Email: send email
Telefono: +31 71 526 9566
Fax: +31 71 526 8275

 Nazionalità Coordinatore Netherlands [NL]
 Totale costo 3˙756˙469 €
 EC contributo 3˙756˙469 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2012-ITN
 Funding Scheme MC-ITN
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-11-01   -   2016-10-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    ACADEMISCH ZIEKENHUIS LEIDEN

 Organization address address: Albinusdreef 2
city: LEIDEN
postcode: 2333 ZA

contact info
Titolo: Mr.
Nome: Ruud
Cognome: Esveld
Email: send email
Telefono: +31 71 526 9566
Fax: +31 71 526 8275

NL (LEIDEN) coordinator 870˙434.20
2    QUEEN MARY UNIVERSITY OF LONDON

 Organization address address: 327 MILE END ROAD
city: LONDON
postcode: E1 4NS

contact info
Titolo: Dr.
Nome: Thorsten
Cognome: Hagemann
Email: send email
Telefono: +44 20 7882 3590
Fax: +44 20 7882 3885

UK (LONDON) participant 573˙413.25
3    UPPSALA UNIVERSITET

 Organization address address: SANKT OLOFSGATAN 10 B
city: UPPSALA
postcode: 751 05

contact info
Titolo: Mrs.
Nome: Pirkko
Cognome: Boox
Email: send email
Telefono: +46 18 4714815
Fax: +46 18 4715077

SE (UPPSALA) participant 523˙150.30
4    STICHTING HET NEDERLANDS KANKER INSTITUUT

 Organization address address: PLESMANLAAN 121
city: AMSTERDAM
postcode: 1066 CX

contact info
Titolo: Dr.
Nome: Henri
Cognome: Van Luenen
Email: send email
Telefono: 31205122097

NL (AMSTERDAM) participant 477˙022.90
5    RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN

 Organization address address: REGINA PACIS WEG 3
city: BONN
postcode: 53113

contact info
Titolo: Ms.
Nome: Daniela
Cognome: Hasenpusch
Email: send email
Telefono: +49 228 737 274
Fax: +49 228 736 479

DE (BONN) participant 447˙437.75
6    TECHNISCHE UNIVERSITAET DRESDEN

 Organization address address: HELMHOLTZSTRASSE 10
city: DRESDEN
postcode: 1069

contact info
Titolo: Mrs.
Nome: Beate
Cognome: Brenner
Email: send email
Telefono: +49 351 463 421 85
Fax: +49 351 463 397 42

DE (DRESDEN) participant 447˙437.75
7    ALLIGATOR BIOSCIENCE AB

 Organization address address: SCHEELEVAGEN 19A
city: LUND
postcode: 22370

contact info
Titolo: Mrs.
Nome: Jennifer
Cognome: Glennon
Email: send email
Telefono: +46 723 044 524
Fax: +46 462 864 290

SE (LUND) participant 226˙772.05
8    SYNOVO GMBH

 Organization address address: Paul Ehrlich Str 15
city: TUEBINGEN
postcode: 72076

contact info
Titolo: Dr.
Nome: Michael
Cognome: Burnet
Email: send email
Telefono: 497072000000
Fax: 497072000000

DE (TUEBINGEN) participant 190˙800.72

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

mice    immune    cell    cells    modified    compartment    underlying    pathways    myeloid    oncology    tumors    therapeutic    tissues    anti    tumor    genetically    human    timcc    therapy    immunology    cellular    genetics    molecular    variety    infiltrating    itn   

 Obiettivo del progetto (Objective)

'The ITN TIMCC brings together eight expert teams from different disciplines within Immunology, Genetics and Oncology, to provide substantive and methodological training in the analysis of the role of the Tumor Infiltrating Myeloid Cell Compartment (TIMCC) of the innate immune system. Leukocytes recruited to (pre)malignant tissues are mainly myeloid cells. They can either prevent or functionally contribute to cancer development. However, the mechanisms underlying pro- versus anti-tumor programming of neoplastic tissues by these immune cells remain obscure. The ITN TIMCC aims to improve anti-tumor therapy by defining general and tumor type specific molecular and cellular immunological pathways (e.g signal transduction and downstream effector pathways) in tumor development and during therapeutic intervention based on an extensive analysis of the infiltrating myeloid cell compartment in human tumor biopsies using a large variety of techniques and functional analysis of the corresponding models of a variety of human tumors, affecting different organs, in a unique cohort of genetically modified mice treated with different types of anti-tumor therapy. The program will train the appointed researchers in a variety of methodology and technology from genomic technologies and bioinformatics via genetically modified mice to the design and application of therapeutic strategies to understand and manipulate the many interactions of the myeloid cell compartment with developing tumors. By defining underlying molecular and cellular pathways new targets will be identified to be explored by the participating SMEs. The program will deliver young researchers equipped with a broad knowledge in immunology, genetics and oncology and insight in the complexity of translational medicine therefore better prepared to meet new challenges in the field.'

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