COSMIC

Community-based scheduled screening and treatment of malaria in pregnancy for improved maternal and infant health: a cluster-randomized trial

 Coordinatore HET KONINKLIJK INSTITUUT VOOR DE TROPEN 

 Organization address address: "Mauritskade, 63"
city: AMSTERDAM
postcode: 1092 AD

contact info
Titolo: Dr.
Nome: Hendricus
Cognome: Schallig
Email: send email
Telefono: 31205665447
Fax: 316971841

 Nazionalità Coordinatore Netherlands [NL]
 Sito del progetto http://www.cosmicmalaria.eu/
 Totale costo 3˙944˙701 €
 EC contributo 2˙997˙218 €
 Programma FP7-HEALTH
Specific Programme "Cooperation": Health
 Code Call FP7-HEALTH-2012-INNOVATION-1
 Funding Scheme CP-FP
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-09-01   -   2016-08-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    HET KONINKLIJK INSTITUUT VOOR DE TROPEN

 Organization address address: "Mauritskade, 63"
city: AMSTERDAM
postcode: 1092 AD

contact info
Titolo: Dr.
Nome: Hendricus
Cognome: Schallig
Email: send email
Telefono: 31205665447
Fax: 316971841

NL (AMSTERDAM) coordinator 468˙815.40
2    CENTRE MURAZ

 Organization address address: Avenue Mamadou Konate
city: BOBO-DIOULASSO
postcode: NA

contact info
Titolo: Ms.
Nome: Ida
Cognome: Ouédraogo
Email: send email
Telefono: +226 7 0346354

BF (BOBO-DIOULASSO) participant 694˙719.00
3    MEDICAL RESEARCH COUNCIL

 Organization address address: NORTH STAR AVENUE POLARIS HOUSE
city: SWINDON
postcode: SN2 1FL

contact info
Titolo: Mr.
Nome: Dembo
Cognome: Kanteh
Email: send email
Telefono: 2204495917

UK (SWINDON) participant 619˙592.00
4    Ministere de la sante

 Organization address address: n/a
city: Cotonou
postcode: 06 BP 3029

contact info
Titolo: Dr.
Nome: Alain
Cognome: Nahum
Email: send email
Telefono: +229 97 592920

BJ (Cotonou) participant 566˙998.00
5    PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE

 Organization address address: Nationalestraat 155
city: ANTWERPEN
postcode: 2000

contact info
Titolo: Ms.
Nome: Eva
Cognome: Mostmans
Email: send email
Telefono: +32 3 2470722
Fax: +32 3 2476359

BE (ANTWERPEN) participant 260˙360.40
6    IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE

 Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
city: LONDON
postcode: SW7 2AZ

contact info
Titolo: Ms.
Nome: Tatjana
Cognome: Tatjana Palalic
Email: send email
Telefono: +44 207 5946265

UK (LONDON) participant 199˙958.00
7    WORLD HEALTH ORGANIZATION.

 Organization address address: Avenue Appia 20
city: GENEVE
postcode: 1211

contact info
Titolo: Dr.
Nome: Melba
Cognome: Gomes
Email: send email
Telefono: +41 22 7913813

CH (GENEVE) participant 186˙775.20

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

coverage    chw    intermittent    community    pregnancy    women    interventions    mip    poor    impact    anaemia    sst    deaths    maternal    anc    countries    pregnant    alone    determine    lbw    infant    iptp    malaria    health    intervention    sp    hmm   

 Obiettivo del progetto (Objective)

'Pregnant women are very susceptible to malaria infection and Malaria in Pregnancy (MiP) is a major cause of maternal anaemia and low birth weight (LBW) that leads to infant mortality, poor growth and development. In low transmission areas, malaria can become severe, resulting in maternal and foetal death. In sub-Saharan Africa (SSA) MiP is responsible for 8–14% of LBW, 3–8% of infant deaths, higher risk of post-partum haemorrhage and >10,000 maternal deaths/year. Prevention like, bed nets and intermittent preventive treatment with sulphadoxine-pyrimethamine (IPTp/SP), is cheap and cost-effective, but coverage achieved by these interventions is low. Therefore, we propose Community Health Workers (CHW) to implement scheduled intermittent screening at community level with RDT of pregnant women and if positive treat with anti-malarials (SST). In addition CHWs will encourage pregnant women to attend antenatal clinics (ANC) for other pregnancy-targeted interventions and IPTp/SP, thereby improving its coverage. This approach combines existing IPTp/SP with SST at village level as an extension of Home based management of malaria (HMM). This low cost (based on existing practice) and simple (diagnosis by RDTs) intervention improves maternal and newborn health and capitalise on an already existing intervention (HMM). The aim of this proposal is to determine the added value (as compared to IPTp/SP alone implemented in health facilities) of community SST of pregnant women implemented through the CHW involved in HMM. Objectives are: 1) Identify bottlenecks for implementation by CHW involved in HMM of SST; 2) determine impact of introducing SST in pregnancy on quality of HMM; 3) determine the impact of SST on ANC attendance and IPTp/SP coverage; 4) determine the impact of SST on LBW, anaemia and placenta malaria; 5) estimate cost-effectiveness of SST as compared to IPTp/SP alone and 6) formulate recommendations for possible implementation of the intervention.'

Introduzione (Teaser)

Low-cost interventions to manage malaria in resource-poor countries are of paramount importance. With a focus on pregnant women, the scope of the COSMIC initiative is to improve maternal and infant health in malaria-endemic countries.

Altri progetti dello stesso programma (FP7-HEALTH)

NEUROMICS (2012)

Integrated European –omics research project for diagnosis and therapy in rare neuromuscular and neurodegenerative diseases

Read More  

NRT (2012)

Phase II clinical trial of PDGF-BB for the neurological regeneration and recovery in Parkinson´s disease

Read More  

NEUROXSYS (2009)

Genomic Regulatory Systems of Human X-linked neurological diseases

Read More