TLEMsafe

Improving safety and predictability of complex musculo-skeletal surgery using a patient-specific navigation system

Coordinatore	UNIVERSITEIT TWENTE    more  Organization address address: DRIENERLOLAAN 5 city: ENSCHEDE postcode: 7522 NB contact info Titolo: Prof. Nome: N Cognome: Verdonschot Email: send email Telefono: 31534892436
Nazionalità Coordinatore	Netherlands [NL]
Totale costo	4˙315˙810 €
EC contributo	3˙060˙720 €
Programma	FP7-ICT Specific Programme "Cooperation": Information and communication technologies
Code Call	FP7-ICT-2009-4
Funding Scheme	CP
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-03-01   -   2014-08-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITEIT TWENTE  Organization address address: DRIENERLOLAAN 5 city: ENSCHEDE postcode: 7522 NB contact info Titolo: Prof. Nome: N Cognome: Verdonschot Email: send email Telefono: 31534892436	NL (ENSCHEDE)	coordinator	0.00
2	AnyBody Technology A/S  Organization address address: Niels Jernes Vej 10 city: Aalborg postcode: 9220 contact info Titolo: Mr. Nome: Per Cognome: Sondrup Email: send email Telefono: 4596354288 Fax: +45 9635 4599	DK (Aalborg)	participant	0.00
3	BRAINLAB AG  Organization address address: KAPELLENSTRASSE 12 city: FELDKIRCHEN postcode: 85622 contact info Titolo: Mr. Nome: Martin Cognome: Immerz Email: send email Telefono: +49 89 99 15 68 0	DE (FELDKIRCHEN)	participant	0.00
4	MATERIALISE NV  Organization address address: TECHNOLOGIELAAN 15 city: HEVERLEE postcode: 3001 contact info Titolo: Dr. Nome: ROEL Cognome: WIRIX-SPEETJENS Email: send email Telefono: +32 16 39 62 81 Fax: +32 16 39 66 00	BE (HEVERLEE)	participant	0.00
5	POLITECHNIKA WARSZAWSKA  Organization address address: PLAC POLITECHNIKI 1 city: WARSZAWA postcode: 00-661 contact info Titolo: Dr. Nome: Robert Cognome: Sitnik Email: send email Telefono: +48 22 234 8283 Fax: +48 22 234 8601	PL (WARSZAWA)	participant	0.00
6	STICHTING KATHOLIEKE UNIVERSITEIT  Organization address address: GEERT GROOTEPLEIN NOORD 9 city: NIJMEGEN postcode: 6525 EZ contact info Titolo: Prof. Nome: Sander Cognome: Geurts Email: send email Telefono: 31243614804 Fax: 31243540529	NL (NIJMEGEN)	participant	0.00

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 Obiettivo del progetto (Objective)

The burden of Musculo-Skeletal (M-S) diseases and prosthetic revision operations is huge and increasing rapidly with the aging population. For patients that require a major surgical intervention, procedures are unsafe, uncertain in outcome and have a high complication rate. The goal of TLEMsafe is to create an ICT-based patient-specific surgical navigation system that helps the surgeon safely reaching the optimal functional result for the patient and is a user friendly training facility for the surgeons. TLEMsafe is developed by generating automated 3-D image-analyzing tools to parameterize the M-S system. The patient-specific parameters are fed into a recently developed M-S model with which the patient-specific functional outcome can be predicted. This consists of a direct effect (e.g. due to the removal of a muscle in a tumor patient), but has also a secondary effect in the sense that the patient will generate adaptive behavior to the altered M-S system. Implementation of the adaptive capacity will be a unique (but essential) feature which allows valid predictions of the functional effects of surgical interventions. The next step is that the surgeon can virtually operate on the patient-specific model after which the model predicts the functional effects. Once the optimal plan is selected, this is fed into a system that allows the surgeon to reproduce the selected surgical plan during the actual surgery TLEMsafe is a navigation system based on innovative ICT tools for training and pre-operative planning. Extensive, innovative validation techniques including quantitative indicators to improve safety (of surgical operation) and quality (highly predictable effects of complex surgery) are included. The emphasis on the M-S pathologies and the adaptive capabilities of the human M-S system creates a unique system. Co-developing the software of the visual and interactive (surgical) parts with clinicians and companies eases the successful introduction to (future) surgeons.