Simultaneous multi-pathway engineering in crop plants through combinatorial genetic transformation: Creating nutritionally biofortified cereal grains for food security


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 Nazionalità Coordinatore Spain [ES]
 Totale costo 2˙290˙046 €
 EC contributo 2˙290˙046 €
 Programma FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call ERC-2008-AdG
 Funding Scheme ERC-AG
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-04-01   -   2014-03-31


# participant  country  role  EC contrib. [€] 

 Organization address address: Placa Victor Siurana 1 1
city: LLEIDA
postcode: 25003

contact info
Titolo: Mr.
Nome: Josep M.
Cognome: Sentis Suñé
Email: send email
Telefono: +34.973.70.20.61
Fax: +34.973.70.22.37

ES (LLEIDA) hostInstitution 2˙290˙046.00

 Organization address address: Placa Victor Siurana 1 1
city: LLEIDA
postcode: 25003

contact info
Titolo: Prof.
Nome: Paul
Cognome: Christou
Email: send email
Telefono: 34 973702693
Fax: 34 973238264

ES (LLEIDA) hostInstitution 2˙290˙046.00


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

bioforce    simultaneous    fundamental    complete    food    plants    multiple    world    gene    transfer    transgenes   

 Obiettivo del progetto (Objective)

'BIOFORCE has a highly ambitious applied objective: to create transgenic cereal plants that will provide a near-complete micronutrient complement (vitamins A, C, E, folate and essential minerals Ca, Fe, Se and Zn) for malnourished people in the developing world, as well as built-in resistance to insects and parasitic weeds. This in itself represents a striking advance over current efforts to address food insecurity using applied biotechnology in the developing world. We will also address fundamental mechanistic aspects of multi-gene/pathway engineering through transcriptome and metabolome profiling. Fundamental science and applied objectives will be achieved through the application of an exciting novel technology (combinatorial genetic transformation) developed and patented by my research group. This allows the simultaneous transfer of an unlimited number of transgenes into plants followed by library-based selection of plants with appropriate genotypes and phenotypes. All transgenes integrate into one locus ensuring expression stability over multiple generations. This proposal represents a new line of research in my laboratory, founded on incremental advances in the elucidation of transgene integration mechanisms in plants over the past two and a half decades. In addition to scientific issues, BIOFORCE address challenges such as intellectual property, regulatory and biosafety issues and crucially how the fruits of our work will be taken up through philanthropic initiatives in the developing world while creating exploitable opportunities elsewhere. BIOFORCE is comprehensive and it provides a complete package that stands to make an unprecedented contribution to food security in the developing world, while at the same time generating new knowledge to streamline and simplify multiplex gene transfer and the simultaneous modification of multiple complex plant metabolic pathways'

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