MICRO(WAVE)-NMR

On-line monitoring of microwave-assisted chemical reactions by small-volume NMR techniques

 Coordinatore UNIVERSIDAD DE CASTILLA - LA MANCHA 

 Organization address address: CALLE ALTAGRACIA 50
city: CIUDAD REAL
postcode: 13071

contact info
Titolo: Ms.
Nome: Maria Llanos
Cognome: Carrion- Varela
Email: send email
Telefono: +34 967 599 354
Fax: +34 967 599 305

 Nazionalità Coordinatore Spain [ES]
 Totale costo 45˙000 €
 EC contributo 45˙000 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-ERG-2008
 Funding Scheme MC-ERG
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-04-01   -   2012-09-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSIDAD DE CASTILLA - LA MANCHA

 Organization address address: CALLE ALTAGRACIA 50
city: CIUDAD REAL
postcode: 13071

contact info
Titolo: Ms.
Nome: Maria Llanos
Cognome: Carrion- Varela
Email: send email
Telefono: +34 967 599 354
Fax: +34 967 599 305

ES (CIUDAD REAL) coordinator 45˙000.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

designed    lower    cell    samples    regarding    fellowship    line    nmr    irradiation    time    chemical    volume    techniques    micro    flow    small    chip    detection    microcoils    continuous    reaction    microwave    coil   

 Obiettivo del progetto (Objective)

'The Micro(wave)- NMR project involves the coupling of continuous flow microwave (MW) chemical reactions with small-volumes Nuclear Magnetic Resonance (NMR) techniques. The aim is the on-line monitoring of a chemical process under continuous-flow microwave irradiation by NMR with the main goal of optimizing a process within less time and lower cost. On one hand, the project combines the unique heating mechanism of microwave irradiation with the safety, reproducibility and facile automation of continuous flow techniques. On the other hand, microcoils NMR will be used as the detection method providing the detection of mass-limited samples as well as more complete structural information than any other analytical technique. It is the first time than NMR will be coupled to the microwave technology for an on-line analysis of the reaction product. For the achievement of the objectives, regarding the microwave set-up, a continuous-flow microwave cell has to be designed. The cell will contain capillary-sized reaction tubes defining a small heated coil that winds in and out of the microwave cavity. Reaction mixtures can be flowed through defining a low reaction volume, in the µL range in order to optimize a chemical process with lower cost. Regarding the NMR set-up, microfluidic chips containing a radiofrequency microcoil (NMR-chip) will be used as the detection method and hyphenated to the microwave reactor by means of capillaries. The use of microcoils for NMR provides a sensitivity enhancement, enabling the detection of samples in the picomole range. Microcoils provide higher signals when the detection volume matches the diameter coil, thus, the detection volume will be very small and in the same range than the reaction volume for a better analysis. The NMR-chip concept has been designed and optimized during my previous Marie Curie Fellowship. The proposed project allows me to share the knowledge acquired during my current Fellowship with my University of origin.'

Altri progetti dello stesso programma (FP7-PEOPLE)

DIVERFOR (2013)

Functional implications of inter- vs. intraspecific trait diversity in European forests

Read More  

DOPAPREDICT (2014)

Functional Analysis of Dopamine Prediction Error Circuits

Read More  

CIRCUIT-HUBS (2008)

Functional connectivity of developing hippocampal networks: characterization of “circuit-hubs”

Read More