COLLREGEN

"Collagen scaffolds for bone regeneration: applied biomaterials, bioreactor and stem cell technology"

Coordinatore	ROYAL COLLEGE OF SURGEONS IN IRELAND    more Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.
Nazionalità Coordinatore	Ireland [IE]
Totale costo	1˙999˙530 €
EC contributo	1˙999˙530 €
Programma	FP7-IDEAS-ERC Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	ERC-2009-StG
Funding Scheme	ERC-SG
Anno di inizio	2009
Periodo (anno-mese-giorno)	2009-11-01   -   2015-09-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	ROYAL COLLEGE OF SURGEONS IN IRELAND  Organization address address: Saint Stephen's Green 123 city: DUBLIN postcode: 2 contact info Titolo: Dr. Nome: Paola Cognome: Della Porta Email: send email Telefono: 35314022393 Fax: 35314022449	IE (DUBLIN)	hostInstitution	1˙999˙530.00
2	ROYAL COLLEGE OF SURGEONS IN IRELAND  Organization address address: Saint Stephen's Green 123 city: DUBLIN postcode: 2 contact info Titolo: Prof. Nome: Fergal Joseph Cognome: O'brien Email: send email Telefono: +353-1-402 2149 Fax: +353-1-402 2355	IE (DUBLIN)	hostInstitution	1˙999˙530.00

Mappa

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 Obiettivo del progetto (Objective)

'Regenerative medicine aims to regenerate damaged tissues by developing functional cell, tissue, and organ substitutes to repair, replace or enhance biological function in damaged tissues. The focus of this research programme is to develop bone graft substitute biomaterials and laboratory-engineered bone tissue for implantation in damaged sites. At a simplistic level, biological tissues consist of cells, signalling mechanisms and extracellular matrix. Regenerative medicine/tissue engineering technologies are based on this biological triad and involve the successful interaction between three components: the scaffold that holds the cells together to create the tissues physical form, the cells that create the tissue, and the biological signalling mechanisms (such as growth factors or bioreactors) that direct the cells to express the desired tissue phenotype. The research proposed in this project includes specific projects in all three areas. The programme will be centred on the collagen-based biomaterials developed in the applicant s laboratory and will incorporate cutting edge stem cell technologies, growth factor delivery, gene therapy and bioreactor technology which will translate to in vivo tissue repair. This translational research programme will be divided into four specific themes: (i) development of novel osteoinductive and angiogenic smart scaffolds for bone tissue regeneration, (ii) scaffold and stem cell therapies for bone tissue regeneration, (iii) bone tissue engineering using a flow perfusion bioreactor and (iv) in vivo bone repair using engineered bone and smart scaffolds.'