BioEGOFET

Electrolyte-Gated Organic Field-Effect BIOsensors

 Coordinatore UNIVERSITE PARIS DIDEROT - PARIS 7 

 Organization address city: PARIS Cedex 13
postcode: F-75205

contact info
Titolo: Ms.
Nome: Anne-Sophie
Cognome: REFLOC'H
Email: send email
Telefono: +33 1 57 27 66 68
Fax: +33 1 57 27 55 47

 Nazionalità Coordinatore France [FR]
 Totale costo 2˙372˙347 €
 EC contributo 1˙830˙000 €
 Programma FP7-ICT
Specific Programme "Cooperation": Information and communication technologies
 Code Call FP7-ICT-2009-4
 Funding Scheme CP
 Anno di inizio 2010
 Periodo (anno-mese-giorno) 2010-02-01   -   2012-05-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITE PARIS DIDEROT - PARIS 7

 Organization address city: PARIS Cedex 13
postcode: F-75205

contact info
Titolo: Ms.
Nome: Anne-Sophie
Cognome: REFLOC'H
Email: send email
Telefono: +33 1 57 27 66 68
Fax: +33 1 57 27 55 47

FR (PARIS Cedex 13) coordinator 0.00
2    ACREO AB.

 Organization address address: ELECTRUM 236
city: KISTA
postcode: 16440

contact info
Nome: Åsa
Cognome: Klingensjö
Email: send email
Telefono: 4686327700
Fax: 4686327710

SE (KISTA) participant 0.00
3    Ani Biotech Oy

 Organization address address: Museokatu
city: Helsinki
postcode: 100

contact info
Titolo: Dr.
Nome: Aimo
Cognome: Niskanen
Email: send email
Telefono: +358 20 155 7514
Fax: +358 20 155 7511

FI (Helsinki) participant 0.00
4    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

 Organization address address: Rue Michel -Ange
city: PARIS
postcode: 75794

contact info
Titolo: Mr.
Nome: Ludovic
Cognome: HAMON
Email: send email
Telefono: +331 42349501
Fax: +331 42349508

FR (PARIS) participant 0.00
5    LINKOPINGS UNIVERSITET

 Organization address address: CAMPUS VALLA
city: LINKOPING
postcode: 581 83

contact info
Titolo: Ms.
Nome: Sophie
Cognome: Lindesvik
Email: send email
Telefono: +461 1363113
Fax: +461 1363270

SE (LINKOPING) participant 0.00
6    TEKNOLOGIAN TUTKIMUSKESKUS VTT

 Organization address address: Vuorimiehentie
city: ESPOO
postcode: 02044 VTT

contact info
Titolo: Prof.
Nome: Inger
Cognome: Vikholm-Lundin
Email: send email
Telefono: +358 20 7223363
Fax: +358 20 7223498

FI (ESPOO) participant 0.00
7    UNIVERSITA DEGLI STUDI DI BARI "ALDO MORO"

 Organization address address: Piazza Umberto I
city: BARI
postcode: 70121

contact info
Titolo: Dr.
Nome: Gianfranco
Cognome: Berardi
Email: send email
Telefono: +39 080 5442062
Fax: +39 080 5442529

IT (BARI) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

bio    ofet    point    label    recognition    sensors    organic    electronic    effect    care    sensitivity    transduction    free   

 Obiettivo del progetto (Objective)

Electronic transduction can open new perspectives for point-of-care diagnosis and treatment monitoring. In this respect, label free, organic field-effect transistor (OFET) sensors have recently raised the interest of the organic-electronic community. The EGOFET biosensor aims at an electronic transduction of a bio-recognition event, eventually leading to an amplified response. The sensor combines the specificity of a defined bio-probe with the label-free and high sensitivity of the field-effect transduction principle. The recognition will be achieved through antigens, antibodies or membrane proteins placed on top of the organic semiconductor, right where the electrical transport occurs in this dielectrics/oxide-free structure. Supramolecular architectures will be used to immobilize the bio-probes into polymeric or phospholipid layers to maximise recognition capabilities and minimize non-specific binding and fouling. High sensitivity will be achieved by exploiting conformational changes and/or charge generation effects occurring upon the recognition process. To attain low-operating voltage and low-power consumption, the OFET will take advantage of the high capacitance offered by the electrolytic or protonic medium used to carry the analyte up to the semi-conductor surface. Implementation of the devices on paper and plastic substrates will be realized by low-cost printing-compatible technologies. The sensors figures of merit will be assessed by exploiting the highly specific biotin/avidin affinity reaction. A proof-of-principle for a point-of-care relevant application, using the immunoassay approach, will be pursued afterwards.

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