PONTE

Efficient Patient Recruitment for Innovative Clinical Trials of Existing Drugs to other Indications

 Coordinatore CENTRE D'EXCELLENCE EN TECHNOLOGIES DE L'INFORMATION ET DE LA COMMUNICATION 

 Organization address city: Charleroi
postcode: 6041

contact info
Titolo: Mr.
Nome: Philippe
Cognome: Massonet
Email: send email
Telefono: 3271490799
Fax: +32 71 490799

 Nazionalità Coordinatore Belgium [BE]
 Totale costo 3˙276˙699 €
 EC contributo 2˙495˙024 €
 Programma FP7-ICT
Specific Programme "Cooperation": Information and communication technologies
 Code Call FP7-ICT-2009-4
 Funding Scheme CP
 Anno di inizio 2010
 Periodo (anno-mese-giorno) 2010-03-01   -   2013-02-28

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    CENTRE D'EXCELLENCE EN TECHNOLOGIES DE L'INFORMATION ET DE LA COMMUNICATION

 Organization address city: Charleroi
postcode: 6041

contact info
Titolo: Mr.
Nome: Philippe
Cognome: Massonet
Email: send email
Telefono: 3271490799
Fax: +32 71 490799

BE (Charleroi) coordinator 0.00
2    Cambridge University Hospitals NHS Foundation Trust

 Organization address address: Hills Rd
city: Cambridge
postcode: CB2 0QQ

contact info
Titolo: Mr.
Nome: Stephen
Cognome: Kelleher
Email: send email
Telefono: +44 1223 217418
Fax: +44 1223 348494

UK (Cambridge) participant 0.00
3    CONSIGLIO NAZIONALE DELLE RICERCHE

 Organization address address: PIAZZALE ALDO MORO
city: ROMA
postcode: 185

contact info
Titolo: Dr.
Nome: Giorgio
Cognome: Iervasi
Email: send email
Telefono: +39 050 3152017
Fax: +39 050 3152166

IT (ROMA) participant 0.00
4    GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER

 Organization address address: Welfengarten
city: HANNOVER
postcode: 30167

contact info
Titolo: Prof.
Nome: Nikolaus
Cognome: Forgo
Email: send email
Telefono: +49 511 7628159
Fax: +49 511 7628290

DE (HANNOVER) participant 0.00
5    INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS

 Organization address address: Patission Str.
city: ATHINA
postcode: 10682

contact info
Titolo: Prof.
Nome: Yannis
Cognome: Vassiliou
Email: send email
Telefono: +30 210 7724374
Fax: +30 210 7722527

EL (ATHINA) participant 0.00
6    LIETUVOS SVEIKATOS MOKSLU UNIVERSITETAS

 Organization address address: A MICKEVICIAUS GATVE
city: KAUNAS
postcode: 44307

contact info
Titolo: Dr.
Nome: Robertas
Cognome: Bunevicius
Email: send email
Telefono: +370 460 30011
Fax: +370 460 30014

LT (KAUNAS) participant 0.00
7    NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS

 Organization address address: CHRISTOU LADA
city: ATHENS
postcode: 10561

contact info
Titolo: Ms.
Nome: Efi
Cognome: Kafentzi
Email: send email
Telefono: +30 210 3689038
Fax: +30 210 3689008

EL (ATHENS) participant 0.00
8    STRATEGIC MEDICINE BV - SMI

 Organization address address: JOHAN VAN OLDENBARNEVELTLAAN
city: DEN HAAG
postcode: 2582NE

contact info
Titolo: Dr.
Nome: Michael
Cognome: Liebman
Email: send email
Telefono: +1 814 6595450
Fax: +1 814 4676334

NL (DEN HAAG) participant 0.00
9    TECHNISCHE UNIVERSITAET DRESDEN

 Organization address address: HELMHOLTZSTRASSE
city: DRESDEN
postcode: 1069

contact info
Titolo: Mr.
Nome: Sven
Cognome: Kreigenfeld
Email: send email
Telefono: +49 35146339744
Fax: +49 35146339742

DE (DRESDEN) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

data    patients    intelligent    clinical    eligible    formulas    drugs    diseases    efficacy    trial    effectiveness    appliance    pharmaceutical    trials   

 Obiettivo del progetto (Objective)

Clinical trials are increasingly considered to be not only a means for evaluating the effectiveness of new medicine and pharmaceutical formulas but also for experimenting on existing drugs and their appliance to new diseases and disorders. Pharmaceutical companies tend to prefer launching modified versions of existing drugs, which generate generous profits while carrying little risk of rejection. Translation into clinical therapy has to overcome substantial barriers at the preclinical and clinical levels. Thus, bridging basic science to clinical practice comprises a new scientific challenge which can result in successful clinical applications with low financial cost. In the aforementioned context, the results yielding from clinical trials, which are testing the effectiveness of existing drugs and pharmaceutical formulas on diseases other than the ones they are currently treating, are closely dependent on the available data and the patients. The efficacy of such trials requires the pursuit of a number of aspects that need to be addressed ranging from the aggregation of data from various heterogeneous distributed sources (such as electronic health records - EHRs) to the intelligent processing of this data based on the clinical trial-specific requirements for choosing the appropriate patients eligible for recruitment. Within this framework, PONTE aims at providing a platform following a Service Oriented Architecture (SOA) approach that will offer intelligent automatic identification of individuals eligible (concerning their safety and clinical trial efficacy) to participate in clinical trials, as these will be designed and planned through a flexible authoring tool, enabling semantic interoperability of clinical care information systems with clinical research information systems and drug and disease knowledge databases, as well as the appliance of advanced data mining techniques and enhanced learning algorithms.

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