VISUALEYES COST

To See or Not to See: The Metabolic Cost of Having Eyes and its Role in the Evolution of Vision

 Coordinatore LUNDS UNIVERSITET 

 Organization address address: Paradisgatan 5c
city: LUND
postcode: 22100

contact info
Titolo: Prof.
Nome: Eric
Cognome: Warrant
Email: send email
Telefono: +46 46 222 9341
Fax: +46 46 222 4425

 Nazionalità Coordinatore Sweden [SE]
 Totale costo 179˙169 €
 EC contributo 179˙169 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2009-IEF
 Funding Scheme MC-IEF
 Anno di inizio 2010
 Periodo (anno-mese-giorno) 2010-10-01   -   2013-01-15

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    LUNDS UNIVERSITET

 Organization address address: Paradisgatan 5c
city: LUND
postcode: 22100

contact info
Titolo: Prof.
Nome: Eric
Cognome: Warrant
Email: send email
Telefono: +46 46 222 9341
Fax: +46 46 222 4425

SE (LUND) coordinator 179˙169.40

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

light    eyes    vision    vivo    energetic    surface    eye    retina    dwelling    energy    did    ecomorphs    vitro    consumption    evolve    blind    individuals    dark    cavefish    demand    performed    rate    mexican    regress    metabolic    evolution    regression    eyed    oxygen    habitats   

 Obiettivo del progetto (Objective)

'The evolution and regression of vision in animals has long interested scientists, and researchers have strived to identify the proximate (how did eyes evolve or regress?) and ultimate (why did eyes evolve or regress?) explanations for the appearance and disappearance of eyes. This Marie Curie proposal will use the Mexican blind cavefish to test whether the metabolic cost of the eye has been a significant selective force in the evolution and regression of vision. The Mexican blind cavefish is model species used in developmental biology, and is useful in the study of visual evolution as it has eyed, surface-dwelling ecomorphs, and non-eyed, cave-dwelling ecomorphs. I will measure the energy demand (oxygen consumption rate) of the eye in eyed ecomorphs using both in vivo and in vitro techniques. In vivo oxygen consumption measurements of the eye will be performed on anaesthetised individuals using oxygen microsensors. The energetic demand of the eye will be compared to the whole body metabolic rate of eyed and non-eyed individuals to infer a metabolic cost of vision. The in vitro oxygen consumption measurements of isolated retina will be performed on a specially constructed device where the incoming light intensity can be varied. The retinal oxygen consumption rate will be measured over a range of light intensities to quantify how the cost of the eye changed as Mexican blind cavefish diversified from surface habitats into caves. It is hypothesised that the energy requirements of the retina will be higher in the dark than that in the light. This project will offer an energetic explanation as to why eyes would be disadvantageous in the absence of light, and why selection would act to regress eyes in dark habitats. By understanding the metabolic cost of eyes, we can also learn about the energetic advantages that must have been gained by evolving vision.'

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