PLASMAQUO

Development of plasmonic quorum sensors for understanding bacterial-eukaryotic cell relations

 Coordinatore ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES 

Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.

 Nazionalità Coordinatore Spain [ES]
 Totale costo 2˙247˙629 €
 EC contributo 2˙247˙629 €
 Programma FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call ERC-2010-AdG_20100224
 Funding Scheme ERC-AG
 Anno di inizio 2011
 Periodo (anno-mese-giorno) 2011-03-01   -   2017-02-28

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSIDAD DE VIGO

 Organization address address: LG CAMPUS LAGOAS MARCOSENDE
city: VIGO PONTEVEDRA
postcode: 36310

contact info
Titolo: Mr.
Nome: Anxo
Cognome: Moreira González
Email: send email
Telefono: +34 986 81 22 98
Fax: +34 986 81 39 19

ES (VIGO PONTEVEDRA) beneficiary 871˙496.30
2    ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES

 Organization address address: PASEO MIRAMON PARQUE TECNOLOGICO DE SAN SEBASTIAN EDIFICIO EMPRESARIAL C 182
city: SAN SEBASTIAN
postcode: 20009

contact info
Titolo: Mr.
Nome: Alfonso
Cognome: Egaña
Email: send email
Telefono: +34 943 005 300
Fax: +34 943 005 301

ES (SAN SEBASTIAN) hostInstitution 1˙376˙133.61
3    ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES

 Organization address address: PASEO MIRAMON PARQUE TECNOLOGICO DE SAN SEBASTIAN EDIFICIO EMPRESARIAL C 182
city: SAN SEBASTIAN
postcode: 20009

contact info
Titolo: Prof.
Nome: Luis Manuel
Cognome: Liz Marzán
Email: send email
Telefono: +34 943 00 53 00
Fax: +34 943 00 53 01

ES (SAN SEBASTIAN) hostInstitution 1˙376˙133.61

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

first    plasmonic    contact    bacteria    colonies    optimized    interaction    qs    mechanisms    external    molecules    bacterial    materials    cells    raman    mixed    nanoparticle    signaling    appropriate    sensing    demonstration   

 Obiettivo del progetto (Objective)

'This proposal aims at the development of novel nanostructured materials based on crystalline assemblies of anisotropic plasmonic (gold/silver) nanoparticles, to be used for the surface enhanced Raman scattering (SERS) detection of quorum sensing (QS) signaling molecules, and to the demonstration of applications of such materials to monitor population kinetics in bacterial colonies and the determination of the interaction mechanisms between mixed colonies and their manipulation through external parameters. This will involve a first stage related to the careful design of the most appropriate nanoparticle morphology and composition, as well as an understanding of their specific assembly processes (both on substrates and in solution), so that the collective plasmonic response will be optimized towards the enhancement of the Raman signal of the probe molecular codes. Coating of the nanoparticle supercrystals with a mesoporous layer will be required to protect them against contact with bacteria and cells, while permitting contact with the QS signaling molecules. Ultimately, when the sensing system has been optimized and its performance demonstrated for monitoring of QS signals and colony growth, two final and important goals will be pursued. First, the interaction between mixed colonies (bacteria-bacteria and bacteria-eukaryotic cell) will be monitored in order to get information about synergic or antagonist (toxicity) QS mechanisms during the growth and proliferation of different bacteria and interspecies. This goal will permit the design of in vitro experiments where a bacterial strain may be manipulated by means of external introduction of the appropriate QS signaling molecules. Finally, the major challenge will be the practical demonstration of the ability of these new materials in this particular configuration for understanding and manipulating the growth and communication of different types of prokaryotic and peukaryotic cells.'

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