Opendata, web and dolomites
H2020 projects about "allosteric"
The page lists 20 projects related to the topic "allosteric".
| # | |||
|---|---|---|---|
| 1 | PentaBrain | Structural studies of mammalian Cys-loop receptors | 2015 |
| 2 | CannaPreg | Development of pregnenolone derivatives as allosteric inhibitors of CB1 cannabinoid receptors for the treatment of schizophrenia and psychotic syndromes | 2015 |
| 3 | nAChR PAM-to-gate | Gating mechanism and pharmacological modulation of nicotinic acetylcholine receptors | 2015 |
| 4 | CONCERT | Description of information transfer across macromolecules by concerted conformational changes | 2015 |
| 5 | HBMAP | Decoding, Mapping and Designing the Structural Complexity of Hydrogen-Bond Networks: from Water to Proteins to Polymers | 2016 |
| 6 | OptoNMDA | Optical strategies to investigate NMDA receptor functional diversity and its therapeutic potential | 2016 |
| 7 | CF_struct | High-Resolution X-ray Structures of Full-Length Cystic Fibrosis Transmembrane Conductance Regulator | 2016 |
| 8 | NMDADYN | NMDA receptor diversity: from molecular dynamics to synaptic physiopathology | 2016 |
| 9 | MARS | Mechanism of allosteric regulation of SHP2 phosphatase and its role in cancer and geneticdiseases: a multidisciplinary computational, structural and biological approach | 2017 |
| 10 | RAMSES | Reactivity and Assembly of Multifunctional, Stimuli-responsive Encapsulation Structures | 2016 |
| 11 | ZIPgeting | Quantitative understanding of target recognition on DNA based on directional zipping processes | 2017 |
| 12 | IVORIaN | RAS/C-RAF interaction: A new pharmacological target in Kras-driven lung cancer. | 2017 |
| 13 | MIDAS | Predictive modelling of GPCR druggable allosteric sites | 2017 |
| 14 | SMALLOSTERY | Single-molecule spectroscopy of coordinated motions in allosteric proteins | 2017 |
| 15 | Target5LO | Targeting 5-lipoxygenase in the context of Acute Myeloid Leukemia | 2018 |
| 16 | AlloGPCR | Allosteric modulation of G-protein Coupled Receptors conformational landscape | 2018 |
| 17 | DYNACOTINE | Signal transduction and allosteric modulation of nicotinic acetylcholine receptors:from ion channel electrophysiology to atomic 3D structures | 2019 |
| 18 | SINSTRO | Unique approach to improving neurological function after stroke with SIN020 | 2019 |
| 19 | EXCHANGE | Dynamic Complexes and Allosteric Regulation of Small Molecule Transporters | 2019 |
| 20 | DEAllAct | Dissecting and Engineering Allosteric Activation in a Biosynthetic Enzyme | 2020 |