Opendata, web and dolomites
H2020 projects about "ligases"
The page lists 19 projects related to the topic "ligases".
| # | |||
|---|---|---|---|
| 1 | RINGE3 | Structural and mechanistic insights into RING E3-mediated ubiquitination | 2015 |
| 2 | IntestineUb | The role of Ubiquitin System on the homeostatic control of stem cell maintenance and differentiation in crypt stem cells | 2016 |
| 3 | CsnCRL | The molecular basis of CULLIN E3 ligase regulation by the COP9 signalosome | 2016 |
| 4 | IMMUNE-EXPRESS | Proteasome-Mediated Gene Expression in Plant Immunity | 2016 |
| 5 | CaLiAT | A novel pathway for generation of building blocks for antibiotic biosynthesis | 2016 |
| 6 | ANCHOR E3s | Anchoring ligandable binding sites at E3 ligase surfaces for plug-and-play PROTACs. | 2016 |
| 7 | ChondUb | Identification and characterisation of novel WWP2 substrates and their role in chondrogenesis and osteoarthritis | 2016 |
| 8 | BCM-UPS | Dissecting the role of the ubiquitin proteasome system in the pathogenesis and therapy of B-cell malignancies | 2016 |
| 9 | TEDCIP | Targeting epigenetic demethylases: development of covalent inhibitors and PROTACs (Proteolysis Targeting Chimeras). | 2017 |
| 10 | LIGER | Identification of novel substrates for ubiquitin ligases involved in cell cycle and cell migration | 2017 |
| 11 | Ub-BAC | Dissecting and targeting ubiquitin networks in the course of bacterial infections | 2017 |
| 12 | Nedd8Activate | How does the ubiquitin-like protein NEDD8 activate ubiquitin ligase machineries? | 2018 |
| 13 | TRIM-NET | Training network in drug discovery targeting TRIM Ubiquitin ligases in disease | 2019 |
| 14 | UbiGolD | Deciphering ubiquitin-dependent regulation of Golgi homeostasis control in neurodegeneration | 2019 |
| 15 | H2AH2B_Propagation | Elucidating the propagation and function of H2A and H2B modifications across DNA replication | 2020 |
| 16 | UBIMOTIF | Short linear interaction motifs as specificity determinants in the ubiquitin system – discovery, mechanisms and therapeutic opportunities | 2019 |
| 17 | FreeATPOC | Towards an instrument-free future of molecular diagnostics at the point-of-care | 2020 |
| 18 | Glue2Degrade | Therapeutic hijacking of E3 Ligases | 2020 |
| 19 | ExploDProteins | Exploiting the DNA damage response to induce degradation of proteins | 2020 |