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Regenerate SIGNED

Self-regenerating Functional Surfaces – Towards a Technology Platform for New Materials and Devices

Total Cost €


EC-Contrib. €






 Regenerate project word cloud

Explore the words cloud of the Regenerate project. It provides you a very rough idea of what is the project "Regenerate" about.

vision    materials    repeated    microscopy    homo    easily    spr    view    spectroscopy    owg    life    degradable    surface    trying    describe    disassembly    layers    clean    geneous    stack    topmost    failing    time    glucose    stays    antimicrobial    intriguing    water    sensor    functionally    device    point    layer    contamination    exemplified    damage    diffusion    feasibility    sequential    reptile    shedding    contaminated    shed    fundamentally    attractive    skin    erosion    ellipsometry    assemble    atomic    further    unresolved    cavities    disintegrate    self    selective    intact    instead    until    films    optical    science    crater    property    obtaining    basic    techniques    thin    waveguide    restored    regenerating    platform    not    polymer    resonance    material    removed    fundamental    eroding    force    surfaces    critical    defective    plasmon    successive    sequentially    entire    significantly    fail    extremely    place    regeneration    extend    selectively    functional   

Project "Regenerate" data sheet

The following table provides information about the project.


Organization address
postcode: 79098

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website
 Total cost 1˙498˙987 €
 EC max contribution 1˙498˙987 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-STG
 Funding Scheme ERC-STG
 Starting year 2015
 Duration (year-month-day) from 2015-05-01   to  2021-04-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Self-regenerating materials are intriguing. If critical properties of a failing material or device could be easily restored, this would significantly extend its life time. In this proposal, we describe our vision of a technology platform for the self-regeneration of surface properties. Functional surfaces fail due to damage or contamination. Instead of trying to make “better” functional materials, we here propose a fundamental change in the design of such materials. We want to make a material that can shed its entire contaminated or defective layer, like a reptile shedding its skin, and present a clean, functional one. By shedding defined layers, instead of just eroding a polymer surface, the emerging surface stays homo¬geneous, and cavities or crater-like erosion are avoided. Further¬more, our vision is a material where we can selectively disintegrate the topmost degradable layer of a stack, while the other degradable layers remain in place. That way, the process can be repeated until all layers of the stack have been sequentially removed. The selective and sequential shedding of polymer layers from a multi-stack, with the aim of obtaining functionally intact successive functional layers, is so far an unresolved and therefore extremely attractive, fundamentally important concept, both from a basic science and an application point of view. We want to demonstrate the feasibility of our concept with two research objectives: (1) the sequential regeneration of a functional surface property, exemplified by antimicrobial activity; (2) the regeneration of the activity of a functional device, exemplified by a glucose sensor. We will assemble our target materials, and study their properties and disassembly using surface plasmon resonance/optical waveguide spectroscopy (SPR/OWG), atomic force microscopy, ellipsometry, and other relevant techniques. We will also develop a method to measure water diffusion through thin films using SPR/OWG.


year authors and title journal last update
List of publications.
2019 Zhuoling Deng, Alexander Schweigerdt, Alexander Norow, Karen Lienkamp
Degradation of Polymer Films on Surfaces: A Model Study with Poly(sebacic anhydride)
published pages: 1900121, ISSN: 1022-1352, DOI: 10.1002/macp.201900121
Macromolecular Chemistry and Physics 220/15 2020-01-28
2015 Franziska Dorner, David Boschert, Alexandra Schneider, Wibke Hartleb, Ali Al-Ahmad, Karen Lienkamp
Toward Self-Regenerating Antimicrobial Polymer Surfaces
published pages: 1337-1340, ISSN: 2161-1653, DOI: 10.1021/acsmacrolett.5b00686
ACS Macro Letters 4/12 2019-07-22
2017 Esther K. Riga, David Boschert, Maria Vöhringer, Vania Tanda Widyaya, Monika Kurowska, Wibke Hartleb, Karen Lienkamp
Fluorescent ROMP Monomers and Copolymers for Biomedical Applications
published pages: 1700273, ISSN: 1022-1352, DOI: 10.1002/macp.201700273
Macromolecular Chemistry and Physics 218/21 2019-07-22
2019 Esther Karolin Riga, Elizabeth Gillies, Karen Lienkamp
Self-Regenerating Antimicrobial Polymer Surfaces via Multilayer-Design-Sequential and Triggered Layer Shedding under Physiological Conditions
published pages: 1802049, ISSN: 2196-7350, DOI: 10.1002/admi.201802049
Advanced Materials Interfaces 2019-07-22
2018 Monika Kurowska, Alice Eickenscheidt, Ali Al-Ahmad, Karen Lienkamp
Simultaneously Antimicrobial, Protein-Repellent, and Cell-Compatible Polyzwitterion Networks: More Insight on Bioactivity and Physical Properties
published pages: 613-626, ISSN: 2576-6422, DOI: 10.1021/acsabm.8b00100
ACS Applied Bio Materials 1/3 2019-07-22
2018 Vania Tanda Widyaya, Claas Müller, Ali Al-Ahmad, Karen Lienkamp
Three-Dimensional, Bifunctional Microstructured Polymer Hydrogels Made from Polyzwitterions and Antimicrobial Polymers
published pages: 1211-1226, ISSN: 0743-7463, DOI: 10.1021/acs.langmuir.8b03410
Langmuir 35/5 2019-07-22
2018 David Boschert, Alexandra Schneider-Chaabane, Andreas Himmelsbach, Alice Eickenscheidt, Karen Lienkamp
Synthesis and Bioactivity of Polymer-Based Synthetic Mimics of Antimicrobial Peptides (SMAMPs) Made from Asymmetrically Disubstituted Itaconates
published pages: 8217-8227, ISSN: 0947-6539, DOI: 10.1002/chem.201800907
Chemistry - A European Journal 24/32 2019-07-22
2018 Esther K. Riga, Jürgen Rühe, Karen Lienkamp
Non-Delaminating Polymer Hydrogel Coatings via C,H-Insertion Crosslinking (CHic)-A Case Study of Poly(oxanorbornenes)
published pages: 1800397, ISSN: 1022-1352, DOI: 10.1002/macp.201800397
Macromolecular Chemistry and Physics 219/23 2019-07-22
2018 Vania Tanda Widyaya, Esther K. Riga, Claas Müller, Karen Lienkamp
Submicrometer-Sized, 3D Surface-Attached Polymer Networks by Microcontact Printing: Using UV-Cross-Linking Efficiency To Tune Structure Height
published pages: 1409-1417, ISSN: 0024-9297, DOI: 10.1021/acs.macromol.7b02576
Macromolecules 51/4 2019-07-22
2018 Roman Erath, Karen Lienkamp
A Degradable and Antimicrobial Surface-Attached Polymer Hydrogel
published pages: 1800198, ISSN: 1022-1352, DOI: 10.1002/macp.201800198
Macromolecular Chemistry and Physics 219/17 2019-07-22

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