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RAIS SIGNED

Scalable, point-of-care and label free microarray platform for rapid detection of Sepsis

Total Cost €

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EC-Contrib. €

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Partnership

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 RAIS project word cloud

Explore the words cloud of the RAIS project. It provides you a very rough idea of what is the project "RAIS" about.

detection    free    bio    sepsis    screening    care    few    fast    potentially    point    interferometric    microarray    platform    diseases    label   

Project "RAIS" data sheet

The following table provides information about the project.

Coordinator
FUNDACIO INSTITUT DE CIENCIES FOTONIQUES 

Organization address
address: AVINGUDA CARL FRIEDRICH GAUSS 3
city: Castelldefels
postcode: 08860
website: www.icfo.eu

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 3˙388˙572 €
 EC max contribution 2˙988˙572 € (88%)
 Programme 1. H2020-EU.2.1.1.6. (Micro- and nanoelectronics and photonics: Key enabling technologies related to micro- and nanoelectronics and to photonics, covering also quantum technologies)
 Code Call H2020-ICT-2014-1
 Funding Scheme /RIA
 Starting year 2015
 Duration (year-month-day) from 2015-01-01   to  2018-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACIO INSTITUT DE CIENCIES FOTONIQUES ES (Castelldefels) coordinator 812˙945.00
2    TRINEAN NV BE (GENTBRUGGE) participant 416˙660.00
3    FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA ES (BARCELONA) participant 370˙358.00
4    MICROTEC GESELLSCHAFT FUR MIKROTECHNOLOGIE MBH DE (DUISBURG) participant 298˙750.00
5    IXSCIENT LIMITED UK (TWICKENHAM MIDDLESEX) participant 264˙375.00
6    DIESSE DIAGNOSTICA SENESE SPA IT (MILANO) participant 250˙450.00
7    FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA ES (BELLATERRA (BARCELONA)) participant 246˙406.00
8    AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS ES (MADRID) participant 153˙736.00
9    BRAHMS GMBH DE (HENNIGSDORF) participant 144˙000.00
10    INSTITUT CATALA DE LA SALUT ES (BARCELONA) participant 30˙891.00
11    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE CH (LAUSANNE) participant 0.00

Mappa

 Project objective

The diagnosis and management of acute Sepsis is a critical area where fast and accurate results can translate into life changing health outcomes for individuals. The overall aim of RAIS is to develop a new point-of-care label-free microarray platform and validate it for quantifying levels of specific Sepsis’ biomarkers. The approach uses a novel interferometric technique ultimately capable of providing very large arrays of tests. Specific objectives and activities include: (i) an optical microarray reader based on a disruptive proprietary design combining interferometric lens-free microscopy and proximity CCD or CMOS image sensing; (ii) a microarray plate, in a proper microfluidic cartridge, consisting of a transparent slide with a novel nano-structured surface geometry to increase the detection sensitivity and covered by specific receptors to capture bio-markers; (iii) their integration in a portable and battery powered label free microarray platform potentially capable of measuring more than 1 million bio-targets simultaneously. The developed technology will be capable to detect micro-ribonucleic acids (microRNAs), interleukins and other specific proteins associated to Sepsis using a few microliters of blood or serum samples, in a concentration of a few pg/ml, within 30 minutes (sample to result) and at a cost per patient of less than 50€. In this way, patients will be put on the right treatment more rapidly, potentially reducing the Sepsis mortality rate of more than 70%, with estimated cost savings of more than €10 billion per year as a consequence of shorter hospital stays, reduced use of unnecessary drugs and lower associated insurance bills. The technical approach, targeted device, application and the addressed market sector are perfectly in line with the call H2020-ICT-2014-1 - Photonics KET - Biophotonics for screening of diseases: Mobile, low-cost point-of-care screening devices for reliable, fast and non- or minimally-invasive detection of diseases.

 Work performed, outcomes and results:  advancements report(s) 

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