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Tissue In Stroke Stratification Using e-ASPECTSTW

Total Cost €


EC-Contrib. €






 TISSUE project word cloud

Explore the words cloud of the TISSUE project. It provides you a very rough idea of what is the project "TISSUE" about.

socioeconomic    stratification    disorders    cerebrovascular    economic    trial    model    position    325    fast    prospective    output    brain    standardised    version    acute    feasibility    unknown    restricted    ltd    plan    imaging    medical    symptom    benefits    thrombolysis    commercial    budget    hospital    burden    aspectstw    revenues    tomography    clinical    stroke    biomarker    nccts    scans    strategy    annual    treatment    easily    275    market    brainomix    indirect    arrive    pricing    participating    ischaemic    accessible    onset    financial    size    additional    device    computed    automated    tissue    ncct    units    clinically    eligible    time    approved    biomarkers    business    leaders    receive    hours    25    full    contrast    neurological    validate    software    profits    reaching    health    intravenous    000    hospitals    patients    benefit    untreated    centre    20    euros    250    worldwide    employment    direct    competition    global    projections   

Project "TISSUE" data sheet

The following table provides information about the project.


Organization address
city: OXFORD
postcode: OX2 7HN
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2014
 Funding Scheme SME-1
 Starting year 2014
 Duration (year-month-day) from 2014-10-01   to  2015-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    BRAINOMIX LIMITED UK (OXFORD) coordinator 50˙000.00


 Project objective

Stroke is a burden with far reaching socioeconomic impact. The only approved treatment in ischaemic stroke is intravenous thrombolysis, which is restricted to 4.5 hours after symptom onset and currently, only 20% of all stroke cases are eligible to receive it. An additional 25% remain untreated because they arrive at the hospital with unknown time of onset.

The objective of the “Tissue In Stroke Stratification Using e-ASPECTSTW” (TISSUE) proposal is to clinically validate the ASPECTS method and its automated version, the medical device software e-ASPECTSTW, as an imaging biomarker on Non-Contrast Computed Tomography (NCCT) brain scans for identifying ischaemic stroke patients with unknown time of onset who can benefit from thrombolysis.

e-ASPECTSTW addresses the growing worldwide market of 3,250,000 patients (275,000 patients in Europe) every year having a stroke with unknown time of onset. The annual global market size of e-ASPECTSTW is 325,000,000 Euros. Users of e-ASPECTSTW will be hospitals worldwide that provide acute stroke treatment. e-ASPECTSTW will be integrated in existing clinical pathways offering a standardised, fast, reliable and easily accessible assessment of NCCTs. This will increase the uptake of thrombolysis and provide significant economic benefits to hospitals and the health system. The commercial exploitation of the project results will enhance the growth of Brainomix Ltd leading to increased revenues, profits, employment and will position Brainomix as leaders in imaging biomarkers for neurological and cerebrovascular disorders.

The output of the feasibility study will be a full business plan, including an analysis of the European and global stroke market, an analysis of direct, indirect and potential competition; a detailed business model and pricing strategy as well as financial projections and a detailed design and budget of the prospective multi-centre clinical trial including the participating stroke units.

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The information about "TISSUE" are provided by the European Opendata Portal: CORDIS opendata.

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