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Cervical cancer detection platform based on novel laser processing

Total Cost €


EC-Contrib. €






 CANCER-TECH project word cloud

Explore the words cloud of the CANCER-TECH project. It provides you a very rough idea of what is the project "CANCER-TECH" about.

worldwide    technique    device    deaths    substrate    vagina    medical    limit    25    route    time    annually    10    quality    lies    connects    novelty    uterus    chip    green       dublin    processed    papillomavirus    start    16    99    reduce    cancers    city    university    biopolymer    synthesis    labels    human    assay    contribution    liquid    detection    immunosensing    cervix    laser    improvement    ultrasensitive    biomedical    rapid    bio    organ    functionalized    ablation    amount    property    independent    prepared    nanoparticles    diagnosed    manufacturing    substantial    sensitive    detect    risk    chemical    agent    scope    ireland    union    relative    enhanced    reported    effecting    molecules    successful    nano    mainly    surfaces    ultrapure    hosted    intellectual    cervical    sensitivity    diagnostic    hpv    germany    women    advantageous    surface    alone    specificity    about    plal    fellowship    nanostructures    cancer    arrows    designed    pulsed    textured    immunoassay    causative    platform    performance    on    ages   

Project "CANCER-TECH" data sheet

The following table provides information about the project.


Organization address
address: Glasnevin
city: DUBLIN
postcode: 9

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Project website
 Total cost 175˙866 €
 EC max contribution 175˙866 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2017-12-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    DUBLIN CITY UNIVERSITY IE (DUBLIN) coordinator 175˙866.00


 Project objective

About 10% of all cancers diagnosed in women worldwide, are cancers of the cervix, the organ that connects the uterus and the vagina. Alone in the European Union over 16,000 deaths are reported annually due to cervical cancer effecting women mainly between the ages of 25 and 50. Within the scope of this fellowship, hosted by Dublin City University (Ireland) in collaboration with Arrows Biomedical GMBH (Germany), a highly sensitive platform to detect Human Papillomavirus (HPV), causative agent of about 99.7% of cervical cancer, will be developed. The proposed diagnostic platform will be based on a laser textured biopolymer as device substrate, functionalized with nanoparticles produced via the Pulsed Laser Ablation in Liquid (PLAL) technique. This on-chip immunoassay will allow rapid detection of the HPV. The novelty of this project lies in the high-quality bio-nanostructures as nano-labels via PLAL designed for ultrasensitive detection of HPV. Two major aspects of this project are: (1) the development of complex nano-labels specifically targeting high risk HPV; and (2) improvement in the performance of the developed assay increasing their sensitivity and specificity, relative to current start of the art. Ultrapure HPV-specific nano-labels will be prepared using pulsed laser ablation in liquid, a green synthesis route independent of any chemical processing. The proposed technique is advantageous due to the enhanced surface activity of laser-generated nanoparticles, which will reduce the amount of sample molecules needed for the successful detection by improving the limit of detection and overall detection time. This project aims at making substantial contribution to the advancement of cancer immunosensing based on a novel on-chip immunoassay design for medical applications. Through this project, the applicant aims to develop intellectual property related to the manufacturing of biomedical devices via laser processed surfaces.


year authors and title journal last update
List of publications.
2017 K. Bagga, R. McCann, F. O\'Sullivan, P. Ghosh, S. Krishnamurthy, A. Stalcup, M. Vázquez, D. Brabazon
Nanoparticle functionalized laser patterned substrate: an innovative route towards low cost biomimetic platforms
published pages: 8060-8069, ISSN: 2046-2069, DOI: 10.1039/C6RA27260F
RSC Advances 7/13 2019-06-13
2016 Ronán McCann, Komal Bagga, Robert Groarke, Apryll Stalcup, Mercedes Vázquez, Dermot Brabazon
Microchannel fabrication on cyclic olefin polymer substrates via 1064 nm Nd:YAG laser ablation
published pages: 603-608, ISSN: 0169-4332, DOI: 10.1016/j.apsusc.2016.06.059
Applied Surface Science 387 2019-06-13
2017 Ronán McCann, Cian Hughes, Komal Bagga, Apryll Stalcup, Mercedes Vázquez, Dermot Brabazon
Pulsed laser deposition of plasmonic nanostructured gold on flexible transparent polymers at atmospheric pressure
published pages: 245303, ISSN: 0022-3727, DOI: 10.1088/1361-6463/aa7193
Journal of Physics D: Applied Physics 50/24 2019-06-13
2017 McCann, R.; Bagga, K.; McCarthy, E.; Groarke, R.; Al-Hamaoy, A.; Stalcup, A.; Vázquez, M.; Brabazon, D.
Carbon Nanoparticle Functionalization of Laser Textured Polymer Surfaces for Chemical and Biological Speciation.
published pages: p63-72., ISSN: 0898-1507, DOI:
Lasers in Engineering Vol. 36 Issue 1-3 2019-06-13
2018 Fereshteh Chekin, Komal Bagga, Palaniappan Subramanian, Roxana Jijie, Santosh K. Singh, Sreekumar Kurungot, Rabah Boukherroub, Sabine Szunerits
Nucleic aptamer modified porous reduced graphene oxide/MoS 2 based electrodes for viral detection: Application to human papillomavirus (HPV)
published pages: 991-1000, ISSN: 0925-4005, DOI: 10.1016/j.snb.2018.02.065
Sensors and Actuators B: Chemical 262 2019-06-13

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