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Cervical cancer detection platform based on novel laser processing

Total Cost €


EC-Contrib. €






 CANCER-TECH project word cloud

Explore the words cloud of the CANCER-TECH project. It provides you a very rough idea of what is the project "CANCER-TECH" about.

deaths    limit    causative    synthesis    agent    pulsed    on       chip    risk    surfaces    textured    women    effecting    cancers    molecules    alone    specificity    time    ultrapure    advantageous    ireland    papillomavirus    contribution    nano    reduce    nanostructures    designed    union    amount    biomedical    medical    device    green    biopolymer    scope    surface    quality    independent    laser    germany    hosted    organ    reported    performance    connects    worldwide    about    chemical    enhanced    improvement    plal    labels    intellectual    lies    novelty    16    technique    university    processed    vagina    substrate    99    diagnostic    25    uterus    nanoparticles    ultrasensitive    city    cervix    detection    route    dublin    annually    relative    cervical    mainly    property    substantial    10    fellowship    sensitivity    platform    start    successful    human    hpv    immunosensing    diagnosed    assay    arrows    prepared    manufacturing    cancer    bio    ablation    rapid    detect    liquid    sensitive    functionalized    ages    immunoassay   

Project "CANCER-TECH" data sheet

The following table provides information about the project.


Organization address
address: Glasnevin
city: DUBLIN
postcode: 9

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Project website
 Total cost 175˙866 €
 EC max contribution 175˙866 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2017-12-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    DUBLIN CITY UNIVERSITY IE (DUBLIN) coordinator 175˙866.00


 Project objective

About 10% of all cancers diagnosed in women worldwide, are cancers of the cervix, the organ that connects the uterus and the vagina. Alone in the European Union over 16,000 deaths are reported annually due to cervical cancer effecting women mainly between the ages of 25 and 50. Within the scope of this fellowship, hosted by Dublin City University (Ireland) in collaboration with Arrows Biomedical GMBH (Germany), a highly sensitive platform to detect Human Papillomavirus (HPV), causative agent of about 99.7% of cervical cancer, will be developed. The proposed diagnostic platform will be based on a laser textured biopolymer as device substrate, functionalized with nanoparticles produced via the Pulsed Laser Ablation in Liquid (PLAL) technique. This on-chip immunoassay will allow rapid detection of the HPV. The novelty of this project lies in the high-quality bio-nanostructures as nano-labels via PLAL designed for ultrasensitive detection of HPV. Two major aspects of this project are: (1) the development of complex nano-labels specifically targeting high risk HPV; and (2) improvement in the performance of the developed assay increasing their sensitivity and specificity, relative to current start of the art. Ultrapure HPV-specific nano-labels will be prepared using pulsed laser ablation in liquid, a green synthesis route independent of any chemical processing. The proposed technique is advantageous due to the enhanced surface activity of laser-generated nanoparticles, which will reduce the amount of sample molecules needed for the successful detection by improving the limit of detection and overall detection time. This project aims at making substantial contribution to the advancement of cancer immunosensing based on a novel on-chip immunoassay design for medical applications. Through this project, the applicant aims to develop intellectual property related to the manufacturing of biomedical devices via laser processed surfaces.


year authors and title journal last update
List of publications.
2017 K. Bagga, R. McCann, F. O\'Sullivan, P. Ghosh, S. Krishnamurthy, A. Stalcup, M. Vázquez, D. Brabazon
Nanoparticle functionalized laser patterned substrate: an innovative route towards low cost biomimetic platforms
published pages: 8060-8069, ISSN: 2046-2069, DOI: 10.1039/C6RA27260F
RSC Advances 7/13 2019-06-13
2016 Ronán McCann, Komal Bagga, Robert Groarke, Apryll Stalcup, Mercedes Vázquez, Dermot Brabazon
Microchannel fabrication on cyclic olefin polymer substrates via 1064 nm Nd:YAG laser ablation
published pages: 603-608, ISSN: 0169-4332, DOI: 10.1016/j.apsusc.2016.06.059
Applied Surface Science 387 2019-06-13
2017 Ronán McCann, Cian Hughes, Komal Bagga, Apryll Stalcup, Mercedes Vázquez, Dermot Brabazon
Pulsed laser deposition of plasmonic nanostructured gold on flexible transparent polymers at atmospheric pressure
published pages: 245303, ISSN: 0022-3727, DOI: 10.1088/1361-6463/aa7193
Journal of Physics D: Applied Physics 50/24 2019-06-13
2017 McCann, R.; Bagga, K.; McCarthy, E.; Groarke, R.; Al-Hamaoy, A.; Stalcup, A.; Vázquez, M.; Brabazon, D.
Carbon Nanoparticle Functionalization of Laser Textured Polymer Surfaces for Chemical and Biological Speciation.
published pages: p63-72., ISSN: 0898-1507, DOI:
Lasers in Engineering Vol. 36 Issue 1-3 2019-06-13
2018 Fereshteh Chekin, Komal Bagga, Palaniappan Subramanian, Roxana Jijie, Santosh K. Singh, Sreekumar Kurungot, Rabah Boukherroub, Sabine Szunerits
Nucleic aptamer modified porous reduced graphene oxide/MoS 2 based electrodes for viral detection: Application to human papillomavirus (HPV)
published pages: 991-1000, ISSN: 0925-4005, DOI: 10.1016/j.snb.2018.02.065
Sensors and Actuators B: Chemical 262 2019-06-13

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