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Neurostella TERMINATED

Evolutionary and developmental origin of the nervous system

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "Neurostella" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAT WIEN 

Organization address
address: UNIVERSITATSRING 1
city: WIEN
postcode: 1010
website: www.univie.ac.at

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Total cost 178˙156 €
 EC max contribution 178˙156 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-03-01   to  0000-00-00

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAT WIEN AT (WIEN) coordinator 178˙156.00

Map

 Project objective

Little is known about the genetic and developmental mechanisms that led to the evolution of the nervous system in the ancestors of eumetazoans. We plan to address the issue by studying a basal metazoan - the cnidarian Nematostella vectensis. The cnidarians are a sister group to bilaterians and possess a surprising complexity of genetic network, yet a relatively simple overall morphology including a diffuse nervous system. By studying the neural progenitors, we aim to address the problem from a developmental point of view. We propose to employ the state-of-the-art technology (transcriptome sequencing, in vivo imaging, transgenesis) in order to gain insight into the molecular characteristics of neural progenitors of Nematostella and to understand how the different populations of neural progenitors relate to neuronal diversity present in Nematostella. We will also analyse the function of a neural progenitor marker SoxB2, among others, in order to determine the role in the genetic hierarchy of the formation of the first nervous systems. Last, we will perform a comparative analysis of Nematostella neural progenitor make up with other cnidarians and bilaterians. This will elucidate the common and distinct features of cnidarian and bilateral nervous systems, which in turn will enable us to reconstruct the common ancestor.

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The information about "NEUROSTELLA" are provided by the European Opendata Portal: CORDIS opendata.

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lastchecktime (2022-12-09 23:15:47) correctly updated