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Neurostella TERMINATED
Evolutionary and developmental origin of the nervous system
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0Neurostella project word cloud
Explore the words cloud of the Neurostella project. It provides you a very rough idea of what is the project "Neurostella" about.
first
sequencing
ancestors
plan
morphology
neuronal
relatively
complexity
diversity
issue
led
populations
eumetazoans
neural
diffuse
group
evolution
nematostella
progenitors
ancestor
soxb2
surprising
view
function
understand
network
hierarchy
cnidarians
bilateral
marker
elucidate
cnidarian
metazoan
nervous
progenitor
vectensis
genetic
reconstruct
developmental
employ
basal
molecular
gain
mechanisms
possess
relate
last
transgenesis
little
bilaterians
perform
turn
imaging
vivo
point
transcriptome
sister
Project "Neurostella" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITAT WIEN
Organization address contact info |
| Coordinator Country | Austria [AT] |
| Total cost | 178˙156 € |
| EC max contribution | 178˙156 € (100%) |
| Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
| Code Call | H2020-MSCA-IF-2014 |
| Funding Scheme | MSCA-IF-EF-ST |
| Starting year | 2016 |
| Duration (year-month-day) | from 2016-03-01 to 0000-00-00 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITAT WIEN | AT (WIEN) | coordinator | 178˙156.00 |
Map
Project objective
Little is known about the genetic and developmental mechanisms that led to the evolution of the nervous system in the ancestors of eumetazoans. We plan to address the issue by studying a basal metazoan - the cnidarian Nematostella vectensis. The cnidarians are a sister group to bilaterians and possess a surprising complexity of genetic network, yet a relatively simple overall morphology including a diffuse nervous system. By studying the neural progenitors, we aim to address the problem from a developmental point of view. We propose to employ the state-of-the-art technology (transcriptome sequencing, in vivo imaging, transgenesis) in order to gain insight into the molecular characteristics of neural progenitors of Nematostella and to understand how the different populations of neural progenitors relate to neuronal diversity present in Nematostella. We will also analyse the function of a neural progenitor marker SoxB2, among others, in order to determine the role in the genetic hierarchy of the formation of the first nervous systems. Last, we will perform a comparative analysis of Nematostella neural progenitor make up with other cnidarians and bilaterians. This will elucidate the common and distinct features of cnidarian and bilateral nervous systems, which in turn will enable us to reconstruct the common ancestor.
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The information about "NEUROSTELLA" are provided by the European Opendata Portal: CORDIS opendata.
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No valid XML
lastchecktime (2024-04-23 19:40:05) correctly updated