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SCME

Selecting, Creating and Modifying Embryos: the ethics of new reproductive genetic technologies

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EC-Contrib. €

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Partnership

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Project "SCME" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD 

Organization address
address: WELLINGTON SQUARE UNIVERSITY OFFICES
city: OXFORD
postcode: OX1 2JD
website: www.ox.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://chrisgyngell.com/editing-selecting--creating-embryos.html
 Total cost 195˙454 €
 EC max contribution 195˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2017-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) coordinator 195˙454.00

Map

 Project objective

For over three decades reproductive technologies have been available which allow parents to select between embryos based on their genetic makeup. Soon two novel ways of influencing a child’s genome could also become available. In 2013, personal genomics company 23andMe received a patent to a technology called ‘Gamete Donor Selection Based on Genetic Calculations.’ This technology would allow individuals accessing assisted reproductive services to choose between sperm or egg donors based on the likelihood of the embryos having a particular genetic makeup. Technologies like this allow parents to create rather than select embryos with desirable genetic characteristics. In addition genetic engineering technologies continue to improve. The recently developed ‘CRISPR’ technique provides a more precise way of altering the genome than previous methods, and is the first modification technology with real potential to be used on human embryos. Technologies like this may allow parents to modify the genetic material of existing embryos.

These developments are seen by some as raising very serious ethical worries, and by others as promising to promote human flourishing. Therefore there is an urgent need to give them systematic ethical scrutiny.

If elected to this fellowship I will conduct a rigorous review of embryo creation, modification and section technologies and their ethical, political and philosophical implications. Built on an in-depth understanding of the science behind these technologies, my project will encompass an analysis of relevant philosophical and ethical issues, before delivering practical policy suggestions. This project will be the first extensive overview of the ethics of embryo creation technologies, the specific ethical issues raised by the CRISPR technique, and the moral and philosophical differences between embryo selection, creation and modification technologies.

 Publications

year authors and title journal last update
List of publications.
2015 Debra J. H. Mathews, Sarah Chan, Peter J. Donovan, Thomas Douglas, Christopher Gyngell, John Harris, Alan Regenberg, Robin Lovell-Badge
CRISPR: A path through the thicket
published pages: 159-161, ISSN: 0028-0836, DOI: 10.1038/527159a
Nature 527/7577 2019-06-18
2016 Christopher Gyngell, Thomas Douglas
Selecting Against Disability: The Liberal Eugenic Challenge and the Argument from Cognitive Diversity
published pages: n/a-n/a, ISSN: 0264-3758, DOI: 10.1111/japp.12199
Journal of Applied Philosophy 2019-06-18
2016 Christopher Gyngell, Thomas Douglas, Julian Savulescu
The Ethics of Germline Gene Editing
published pages: , ISSN: 0264-3758, DOI: 10.1111/japp.12249
Journal of Applied Philosophy 2019-06-18
2016 Christopher Gyngell, Michael Selgelid
Twenty-First-Century Eugenics
published pages: , ISSN: , DOI: 10.1093/oxfordhb/9780199981878.013.7
Oxford Handbooks Online 2019-06-18
2016 Chris Gyngell, Michael J. Selgelid
Human Enhancement: Conceptual Clarity and Moral Significance
published pages: 111-126, ISSN: , DOI: 10.1093/acprof:oso/9780198754855.003.0008
The Ethics of Human Enhancement 2019-06-18
2017 Christopher Gyngell
Gene editing and the health of future generations
published pages: 14107681770561, ISSN: 0141-0768, DOI: 10.1177/0141076817705616
Journal of the Royal Society of Medicine 2019-06-18

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