Opendata, web and dolomites


Emergence of novel phenotypes in co-evolving biological systems: allelic diversification and dominance at the Self-incompatibility locus in Arabidopsis.

Total Cost €


EC-Contrib. €






 NOVEL project word cloud

Explore the words cloud of the NOVEL project. It provides you a very rough idea of what is the project "NOVEL" about.

interactions    evolution    fine    theoretical    interaction    components    manner    sporophytic    powerful    recognition    self    biology    genetics    ancestral    male    coordinated    rnas    predict    small    arabidopsis    phenotypic    underlying    pollen    species    evolutionary    incompatibility    fitness    closely    delicto    empirical    revealing    ecological    threefold    proteins    flagrante    alphabet    sequences    molecular    catch    organization    organisms    biological    functional    landscapes    individual    multidisciplinary    female    coding    diversification    course    nucleotide    phenotype    natural    parts    context    population    levels    interact    genes    sites    nature    poorly    model    emergence    tractable    reproductive    constraints    dominance    plants    alleles    basic    resurrection    co    raises    entails    unveil    place    regulatory    combination    combining    intricate    transgenic    populations    fraction    novelty    outcrossing    arise    variation    protein    genomics    whereby    decrypt    fundamental    evolve    question    rejection    jointly    recessivity    lacking    mechanistic   

Project "NOVEL" data sheet

The following table provides information about the project.


Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website
 Total cost 1˙760˙880 €
 EC max contribution 1˙760˙880 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-CoG
 Funding Scheme ERC-COG
 Starting year 2015
 Duration (year-month-day) from 2015-10-01   to  2020-09-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

The emerging field of systems biology is revealing the intricate nature of biological organisms, whereby a large fraction of their individual components (genes, proteins, regulatory elements) interact with several others. The co-evolutionary processes that this entails raises the question of how phenotypic novelty may arise in the course of evolution, since all parts of the system have to evolve in a coordinated manner if the phenotype is to remain functional. For most biological systems, however, we are lacking even basic insight into the fine-scale mechanistic constraints and the underlying ecological context. In this project, we will focus on the sporophytic self-incompatibility system in outcrossing Arabidopsis species, a model biological system in which two distinct co-evolutionary processes are becoming well-understood: 1) between the male and female reproductive proteins allowing self-pollen recognition and rejection and 2) between small non-coding RNAs and their target sites that jointly control the dominance/recessivity interactions between self-incompatibility alleles. By studying these two model systems, we will aim to catch the emergence of functional and regulatory novelty in flagrante delicto. We will take a multidisciplinary approach combining theoretical and empirical population genetics, evolutionary genomics and ancestral protein resurrection using transgenic plants. Our goal is threefold: 1) decrypt the molecular alphabet of the interaction between co-evolving nucleotide sequences, 2) predict and evaluate the fitness landscapes upon which the two co-evolutionary processes are taking place and 3) exploit natural variation in closely related species to unveil the kind of co-evolutionary process in natural populations. Our combination of various powerful approaches in a tractable model system should provide insight on diversification, a poorly understood but fundamental evolutionary process that is taking place at all levels of organization.


year authors and title journal last update
List of publications.
2017 Pierre Saumitou-Laprade, Philippe Vernet, Xavier Vekemans, Vincent Castric, Gianni Barcaccia, Bouchaïb Khadari, Luciana Baldoni
Controlling for genetic identity of varieties, pollen contamination and stigma receptivity is essential to characterize the self-incompatibility system of Olea europaea L.
published pages: 860-866, ISSN: 1752-4571, DOI: 10.1111/eva.12498
Evolutionary Applications 10/9 2020-04-23
2017 Sier-Ching Chantha, Adam C. Herman, Vincent Castric, Xavier Vekemans, William Marande, Daniel J. Schoen
The unusual S locus of Leavenworthia is composed of two sets of paralogous loci
published pages: 1247-1255, ISSN: 0028-646X, DOI: 10.1111/nph.14764
New Phytologist 216/4 2020-04-23
2017 Takashi Tsuchimatsu, Pauline M. Goubet, Sophie Gallina, Anne-Catherine Holl, Isabelle Fobis-Loisy, Hélène Bergès, William Marande, Elisa Prat, Dazhe Meng, Quan Long, Alexander Platzer, Magnus Nordborg, Xavier Vekemans, Vincent Castric
Patterns of Polymorphism at the Self-Incompatibility Locus in 1,083 Arabidopsis thaliana Genomes
published pages: , ISSN: 0737-4038, DOI: 10.1093/molbev/msx122
Molecular Biology and Evolution 2020-04-23
2017 Polina Yu. Novikova, Takashi Tsuchimatsu, Samson Simon, Viktoria Nizhynska, Viktor Voronin, Robin Burns, Olga M. Fedorenko, Svante Holm, Torbjörn Säll, Elisa Prat, William Marande, Vincent Castric, Magnus Nordborg
Genome sequencing reveals the origin of the allotetraploid Arabidopsis suecica
published pages: msw299, ISSN: 0737-4038, DOI: 10.1093/molbev/msw299
Molecular Biology and Evolution 2020-04-23

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "NOVEL" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "NOVEL" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

MAMEMS (2020)

Mount Athos in Medieval Eastern Mediterranean Society: Contextualizing the History of a Monastic Republic (ca. 850-1550)

Read More  


Evolving communication systems in response to altered sensory environments

Read More  


Efficient Conversion of Quantum Information Resources

Read More