Explore the words cloud of the CellViewer project. It provides you a very rough idea of what is the project "CellViewer" about.
The following table provides information about the project.
FUNDACIO CENTRE DE REGULACIO GENOMICA
|Coordinator Country||Spain [ES]|
|Total cost||3˙988˙752 €|
|EC max contribution||3˙988˙752 € (100%)|
1. H2020-EU.1.2.1. (FET Open)
|Duration (year-month-day)||from 2016-02-01 to 2020-05-31|
Take a look of project's partnership.
|1||FUNDACIO CENTRE DE REGULACIO GENOMICA||ES (BARCELONA)||coordinator||2˙086˙668.00|
|2||THE HEBREW UNIVERSITY OF JERUSALEM||IL (JERUSALEM)||participant||792˙500.00|
|3||Idea Bio-Medical Ltd.||IL (Rehovot)||participant||687˙500.00|
|4||FUNDACIO INSTITUT DE CIENCIES FOTONIQUES||ES (Castelldefels)||participant||293˙334.00|
|5||LABORATORY IMAGING SRO||CZ (PRAHA)||participant||128˙750.00|
|6||EUROPEAN MOLECULAR BIOLOGY LABORATORY||DE (HEIDELBERG)||participant||0.00|
In this ambitious and multi-disciplinary proposal, we aim to develop new technologies that will allow us to visualize in single cells, in parallel and at the systems level, DNA, mRNAs and proteins with nanoscale resolution. We will refer to these novel technologies as the ‘CellViewer’: a unique cutting-edge high-throughput super-resolution (SR) microscopy approach (including new hardware and software development) to collect at high-resolution a large amount of spatial and dynamic information in single cells. ‘CellViewer’ will allow us to study the mechanisms of mouse embryonic stem cell (mESC) self-renewal and differentiation upon application of specific stimuli, as a specific test case. We will analyse in single cells with high throughput, DNA remodelling at multiple specific gene loci and their corresponding production, distribution and kinetics of mRNA and protein products. We will collect a large amount of dynamic and nanoscale spatial information that will lead us to build predictive models of the phenotypic output from specific input stimuli. In turn, we will be able to develop a mechanistic understanding of how mESCs maintain their stemness or commit to differentiation. The partners of CellViewer are internationally recognized experts from academia and industry in the fields of stem cell and chromatin biology, super-resolution microscopy, quantitative modelling of biological systems, and hardware and software development. This team as a whole is uniquely suited to bring Systems Biology into the era of single cell analysis, which will be a paradigm shift in the way cellular systems will be studied.
|Quality plan||Documents, reports||2020-02-07 10:11:20|
|Project website||Websites, patent fillings, videos etc.||2020-02-07 10:11:20|
Take a look to the deliverables list in detail: detailed list of CellViewer deliverables.
|year||authors and title||journal||last update|
Francesco Sottile, Francesco Aulicino, Ilda Theka & Maria Pia Cosma
Mesenchymal stem cells generate distinct functional hybrids in vitro via cell fusion or entosis
published pages: , ISSN: 2045-2322, DOI: 10.1038/srep36863
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The information about "CELLVIEWER" are provided by the European Opendata Portal: CORDIS opendata.