INNODERM SIGNED
Innovative Dermatology Healthcare based on Label-Free Spectral Optoacoustic Mesoscopy
Total Cost €
0EC-Contrib. €
0Partnership
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0INNODERM project word cloud
Explore the words cloud of the INNODERM project. It provides you a very rough idea of what is the project "INNODERM" about.
Project "INNODERM" data sheet
The following table provides information about the project.
| Coordinator |
TECHNISCHE UNIVERSITAET MUENCHEN
Organization address contact info |
| Coordinator Country | Germany [DE] |
| Project website | http://www.innoderm2020.eu |
| Total cost | 4˙595˙125 € |
| EC max contribution | 3˙869˙879 € (84%) |
| Programme |
1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT)) |
| Code Call | H2020-ICT-2015 |
| Funding Scheme | IA |
| Starting year | 2016 |
| Duration (year-month-day) | from 2016-03-01 to 2021-02-28 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | TECHNISCHE UNIVERSITAET MUENCHEN | DE (MUENCHEN) | coordinator | 1˙432˙350.00 |
| 2 | HUMANITAS UNIVERSITY | IT (PIEVE EMANUELE) | participant | 745˙288.00 |
| 3 | ITHERA MEDICAL GMBH | DE (MUNCHEN) | participant | 724˙868.00 |
| 4 | RAYFOS LTD | UK (BASINGSTOKE) | participant | 496˙133.00 |
| 5 | SONAXIS SA | FR (BESANCON) | participant | 471˙238.00 |
| 6 | UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA | IT (ROMA) | participant | 0.00 |
Map
Project objective
Multispectral Optoacoustic Tomography (MSOT) brings a revolution to bio-optical imaging. Being insensitive to photon scattering, MSOT dramatically improves upon conventional bio-optic barriers by enabling (1) three-dimensional high-resolution optical imaging deep inside tissues (several millimetres to centimetres), by (2) high-scalability, ranging from optical-resolution microscopy to acoustic-resolution optical mesoscopy and macroscopy and by (3) novel label-free anatomical, physiological and molecular contrast at the tissue and single-cell-level, based on spectrally-resolved optical absorption. MSOT, originally supported by an ERC Advanced Award (2008) (TUM: Prof. Ntziachristos), is already commercialized by iThera Medical for macroscopy with systems sold around the world for small animal imaging. In parallel, ERC MSOT funding developed a mesoscopic implementation, termed raster-scan optoacoustic mesoscopy (RSOM), which has demonstrated innovative imaging capacity at 1-5mm depths. Driven by leading dermatologists (TUM: Prof. Biedermann; SUR: Prof. Costanzo) and market leader SMEs in optoacoustic and ultrasound technology (iThera, Rayfos, Sonaxis), INNODERM will design and prototype a handheld, portable, scalable, label-free RSOM device for point-of care dermatology applications, based on recommendations developed under an ERC proof of concept grant (2013) on MSOT. INNODERM brings together key photonic & ultrasound technologies and will validate the technical and economic viability of RSOM in dermatology suites for fast diagnosis and skin disease monitoring. RSOM can go beyond the abilities of current optical or optoacoustic devices and offer a paradigm shift in dermatology imaging, substantiating successful business cases.
Deliverables
| Functioning RSOM2 prototype | Other | 2019-09-04 15:23:38 |
| Final single element transducers for RSOM with low noise amplification | Other | 2019-09-04 15:23:38 |
| Report or publication on algorithmic acceleration | Documents, reports | 2019-09-04 15:23:38 |
| Report on LiNBO3 vs PZT element transducers | Documents, reports | 2019-09-04 15:23:38 |
| Report or publication on read-electronics speeds and efficiency | Documents, reports | 2019-09-04 15:23:38 |
| Report on performance of RSOM2 | Documents, reports | 2019-09-04 15:23:38 |
| Update, communication kit | Websites, patent fillings, videos etc. | 2019-09-04 15:23:38 |
| Press release, project launch | Websites, patent fillings, videos etc. | 2019-09-04 15:23:38 |
| First communication kit | Websites, patent fillings, videos etc. | 2019-09-04 15:23:38 |
| Project web site | Websites, patent fillings, videos etc. | 2019-09-04 15:23:38 |
Take a look to the deliverables list in detail: detailed list of INNODERM deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2017 |
Mathias Schwarz, Natalie Garzorz-Stark, Kilian Eyerich, Juan Aguirre, Vasilis Ntziachristos Motion correction in optoacoustic mesoscopy published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-11277-y |
Scientific Reports 7/1 | 2019-09-04 |
| 2017 |
Juan Aguirre, Mathias Schwarz, Natalie Garzorz, Murad Omar, Andreas Buehler, Kilian Eyerich, Vasilis Ntziachristos Precision assessment of label-free psoriasis biomarkers with ultra-broadband optoacoustic mesoscopy published pages: 68, ISSN: 2157-846X, DOI: 10.1038/s41551-017-0068 |
Nature Biomedical Engineering 1/5 | 2019-09-04 |
| 2017 |
Alessandra Narcisi, Rebecca Favaro, Antonio Costanzo Diagnostic imaging: Listening in to skin disease published pages: 76, ISSN: 2157-846X, DOI: 10.1038/s41551-017-0076 |
Nature Biomedical Engineering 1/5 | 2019-09-04 |
| 2017 |
M. Talamonti, M. Galluzzo, J.M. van den Reek, E.M. de Jong, J.L.W. Lambert, P. Malagoli, L. Bianchi, A. Costanzo Role of the HLA-C*06 allele in clinical response to ustekinumab: evidence from real life in a large cohort of European patients published pages: 489-496, ISSN: 0007-0963, DOI: 10.1111/bjd.15387 |
British Journal of Dermatology 177/2 | 2019-09-04 |
| 2017 |
Mathias Schwarz, Dominik Soliman, Murad Omar, Andreas Buehler, Saak V. Ovsepian, Juan Aguirre, Vasilis Ntziachristos Optoacoustic Dermoscopy of the Human Skin: Tuning Excitation Energy for Optimal Detection Bandwidth with Fast and Deep Imaging in vivo published pages: 1-1, ISSN: 0278-0062, DOI: 10.1109/TMI.2017.2664142 |
IEEE Transactions on Medical Imaging | 2019-09-04 |
| 2019 |
Juan Aguirre, Andrei Berezhnoi, Hailong He, Mathias Schwarz, Benedikt Hindelang, Murad Omar, Vasilis Ntziachristos Motion quantification and automated correction in clinical RSOM published pages: 1-1, ISSN: 0278-0062, DOI: 10.1109/tmi.2018.2883154 |
IEEE Transactions on Medical Imaging | 2019-09-04 |
| 2019 |
Murad Omar, Juan Aguirre, Vasilis Ntziachristos Optoacoustic mesoscopy for biomedicine published pages: , ISSN: 2157-846X, DOI: 10.1038/s41551-019-0377-4 |
Nature Biomedical Engineering | 2019-09-04 |
| 2018 |
Antonios Stylogiannis, Ludwig Prade, Andreas Buehler, Juan Aguirre, George Sergiadis, Vasilis Ntziachristos Continuous wave laser diodes enable fast optoacoustic imaging published pages: 31-38, ISSN: 2213-5979, DOI: 10.1016/j.pacs.2017.12.002 |
Photoacoustics 9 | 2019-09-04 |
| 2018 |
B. Hindelang, J. Aguirre, M. Schwarz, A. Berezhnoi, K. Eyerich, V. Ntziachristos, T. Biedermann, U. Darsow Non-invasive imaging in dermatology and the unique potential of Raster-Scan Optoacoustic Mesoscopy (RSOM) published pages: , ISSN: 0926-9959, DOI: 10.1111/jdv.15342 |
Journal of the European Academy of Dermatology and Venereology | 2019-09-04 |
| 2018 |
Andrei Berezhnoi, Mathias Schwarz, Andreas Buehler, Saak V. Ovsepian, Juan Aguirre, Vasilis Ntziachristos Assessing hyperthermia-induced vasodilation in human skin in vivo using optoacoustic mesoscopy published pages: e201700359, ISSN: 1864-063X, DOI: 10.1002/jbio.201700359 |
Journal of Biophotonics 11/11 | 2019-09-04 |
| 2018 |
J. Aguirre, B. Hindelang, Andrei Berezhnoi, U. Darsow, F. Lauffer, K. Eyerich, T. Biedermann, V. Ntziachristos Assessing nailfold microvascular structure with ultra-wideband raster-scan optoacoustic mesoscopy published pages: 31-37, ISSN: 2213-5979, DOI: 10.1016/j.pacs.2018.02.002 |
Photoacoustics 10 | 2019-09-04 |
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