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COBIOPHAD

COMPACT BIOPHOTONIC PLATFORM FOR DRUG ALLERGY DIAGNOSIS

Total Cost €

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EC-Contrib. €

0

Partnership

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Project "COBIOPHAD" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAT POLITECNICA DE VALENCIA 

Organization address
address: CAMINO DE VERA SN EDIFICIO 3A
city: VALENCIA
postcode: 46022
website: www.upv.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://www.cobiophad.eu
 Total cost 4˙288˙094 €
 EC max contribution 3˙734˙780 € (87%)
 Programme 1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
 Code Call H2020-ICT-2015
 Funding Scheme IA
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2019-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAT POLITECNICA DE VALENCIA ES (VALENCIA) coordinator 1˙026˙678.00
2    STIFTELSEN SINTEF NO (TRONDHEIM) participant 462˙945.00
3    CENTRE HOSPITALIER UNIVERSITAIRE MONTPELLIER FR (MONTPELLIER) participant 451˙932.00
4    FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA ES (VALENCIA) participant 364˙687.00
5    DR. FOOKE-ACHTERRATH LABORATORIEN GMBH DE (NEUSS) participant 314˙978.00
6    STRATEC CONSUMABLES GMBH AT (ANIF) participant 304˙097.00
7    BIOTRONICS 3D LIMITED UK (LONDON) participant 211˙596.00
8    OPTOELECTRONICA - 2001 SA RO (BUCHAREST) participant 159˙300.00
9    EUREXPLOIT LTD UK (LONDON) participant 153˙128.00
10    SINTEF AS NO (TRONDHEIM) participant 137˙475.00
11    LUMENSIA SENSORS SL ES (VALENCIA) participant 76˙733.00
12    DAS PHOTONICS SL ES (VALENCIA) participant 38˙854.00
13    SONY DADC AUSTRIA AT (ANIF) participant 32˙373.00

Map

 Project objective

Drug hypersensitivity to antibiotics, mainly Beta-lactams (BLCs) affects more than 2.5 million European citizens. Moreover, preventable adverse drug reactions are estimated in additional hospitalization costs of 1750-4500 €/patient. Currently, the allergy diagnosis is mainly based on the information given by invasive, single, and risky in vivo assays. In daily practice, few in vitro diagnostic methods are available and only used at the tertiary health services. These tests also lack of sensitivity (>0.35 kUA/L) and selectivity (<98%), resulting in an inaccurate diagnosis, analyze few drugs allergens (5), are time consuming (60-180 min), and expensive (30 €/allergen).

COBIOPHAD aims the development of an innovative in vitro diagnostic (IVD) device for diagnosis of IgE-mediated drug allergies by building an integrated biophotonic system based on compact disc technology. For that, key enabling technologies will be integrated in order to achieve high sensitive (<0.1 kUA/L), selective (>98%), multiplexed (10 BLCs), rapid (30 min), and low-cost (2.4 €/allergen) drug allergy test. The solution involves an advanced approach to the diagnosis and management of drug allergy with the aim to ameliorate patient safety.

The consortium comprises multidisciplinary knowledge on optics, electronics, advanced materials, biotechnology, smart microstructures, microfluidics, surface/organic chemistry, allergy, manufacturing systems, and telecom networking. Also, the key industrial actors, present in the consortium, will contribute to the manufacturing and placing the product on the IVD market.

 Deliverables

List of deliverables.
Final Communication kit about the project Websites, patent fillings, videos etc. 2020-01-29 12:43:06
New diagnostic device (COBIOPHAD) characteristics and performances Documents, reports 2020-01-29 12:43:06
Work-up of new international recommendations for the patient allergy medical care Documents, reports 2020-01-29 12:43:06
Short film magazine Websites, patent fillings, videos etc. 2020-01-29 12:43:06
Report on integration and assays testing Documents, reports 2020-01-29 12:43:06
Technical dossier including the analysis of the compliance with the defined requirements Documents, reports 2020-01-29 12:43:06
First Communication kit about the project Websites, patent fillings, videos etc. 2020-01-29 12:43:05
Web site Websites, patent fillings, videos etc. 2020-01-29 12:43:06
Second Communication kit about the project Websites, patent fillings, videos etc. 2020-01-29 12:43:06
Project presentation Websites, patent fillings, videos etc. 2020-01-29 12:43:06

Take a look to the deliverables list in detail:  detailed list of COBIOPHAD deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Dr Ian A. McKay
COBIOPHAD MAGAZINE
published pages: , ISSN: , DOI:
2020-01-29
2019 Elizaveta Vereshchagina, Sergi Morais, Luis A. Tortajada-Genaro, Angel Maquieira, Estrella Fernandez, Teresa Molina, Veaceslav Linte, Brindus Comanescu, Michal M. Mielnik, Erik Andreassen, Anna Franquesa-Vazquez, Werner Balika5, Alfredo Sáez, Sergio Peransi Llopis
A NOVEL DIAGNOSTIC DEVICE FOR RAPID TESTING OF ANTIBIOTIC ALLERGIES: FOCUS ON FLUIDIC DESIGN AND MANUFACTURING OF DISPOSABLE DISCS
published pages: , ISSN: , DOI:
2020-01-29
2016 A. Maquierira
ß-lactams antibiotics allergy
published pages: 212-213, ISSN: 2054-2631, DOI:
HORIZON 2020 PROJECTS: PORTAL 10 April 2016 2020-01-29
2016 N. Offermann, M. Plum, U. Hübner, K. Rathloff, I. Braren, M. Fooke, E. Spillner
Human serum substitution by artificial sera of scalable allergen reactivity based on polyclonal antibodies and chimeras of human FcγRI and IgE domains
published pages: 1794-1799, ISSN: 0105-4538, DOI: 10.1111/all.13038
Allergy 71/12 2020-01-29
2017 E.Vereshchagina, M.Mielnik, E.Andreassen Written by I.Rambæk
Tryggere antibiotikabruk med ny allergitest (Norwegian)New allergy test promises safer antibiotic use (English)
published pages: , ISSN: 0802-085X, DOI:
Gemini 2020-01-29
2017 E. Vereshchagina, E. Andreassen, R.H. Gaarder, M.M. Mielnik
SYNERGY OF 3D PRINTING AND INJECTION MOLDING: A NEW PROTOTYPING METHOD FOR RAPID DESIGN OPTIMIZATION AND MANUFACTURING OF MICROFLUIDIC DEVICES
published pages: , ISSN: , DOI:
Proceedings of the The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (Microtas17) Annual 2020-01-29

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The information about "COBIOPHAD" are provided by the European Opendata Portal: CORDIS opendata.

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