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VIVALDI SIGNED

Preventing and mitigating farmed bivalve diseases

Total Cost €

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EC-Contrib. €

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Partnership

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 VIVALDI project word cloud

Explore the words cloud of the VIVALDI project. It provides you a very rough idea of what is the project "VIVALDI" about.

industry    virus    solutions    bivalves    health    crassostrea    vibrio    pathogen    host    venerupis    diseases    effect    biology    committed    mitigation    global    shellfish    molecular    genetics    galloprovincialis    levels    outbreaks    prevention    simultaneously    farmed    overarching    ostreae    splendidus    mechanisms    tapetis    oyster    combined    sustainability    collaborative    mussels    food    disciplinary    competitiveness    epidemiology    advantages    integrate    bonamia    diagnostic    oshv    molecules    harmful    vivaldi    drugs    flat    basic    confidence    pacific    pathogens    ostrea    models    vitro    vivo    complementary    exposed    pecten    clams    parasite    edulis    species    cultured    gigas    animals    virulence    tools    recognising    cover    aestuarianus    practical    expertises    broad    immunology    bivalve    omic    effort    breeding    mytilus    scallops    safety    pathology    harveyi    trans    innovative    risks    pathogenesis    resistant    industrial    genomics    farm    disease    dissect    either    animal    immune    philipinarum    maximus   

Project "VIVALDI" data sheet

The following table provides information about the project.

Coordinator
INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER 

Organization address
address: 1625 ROUTE DE SAINTE ANNE ZONE INDUSTRIELLE DE LA POINTE DU DIABLE
city: PLOUZANE
postcode: 29280
website: http://www.ifremer.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://www.vivaldi-project.eu
 Total cost 5˙414˙417 €
 EC max contribution 4˙503˙082 € (83%)
 Programme 1. H2020-EU.3.2. (SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy)
 Code Call H2020-SFS-2015-2
 Funding Scheme RIA
 Starting year 2016
 Duration (year-month-day) from 2016-03-01   to  2020-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER FR (PLOUZANE) coordinator 727˙762.00
2    THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS UK (LONDON) participant 448˙656.00
3    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) participant 390˙000.00
4    INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES ES (CALDES DE MONTBUI BARCELONA) participant 371˙273.00
5    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 299˙993.00
6    ATLANTIUM TECHNOLOGIES LTD IL (Beit Shemesh) participant 215˙285.00
7    LABOGENA DNA FR (RENNES) participant 202˙886.00
8    UNIVERSITA DEGLI STUDI DI PADOVA IT (PADOVA) participant 200˙000.00
9    UNIVERSITA DEGLI STUDI DI TRIESTE IT (TRIESTE) participant 199˙983.00
10    UNIVERSITA DEGLI STUDI DI GENOVA IT (GENOVA) participant 199˙230.00
11    UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK IE (Cork) participant 178˙125.00
12    STICHTING WAGENINGEN RESEARCH NL (WAGENINGEN) participant 165˙337.00
13    SYNDICAT DES SELECTIONNEURS AVICOLES ET AQUACOLES FRANCAIS FR (NOUZILLY) participant 150˙001.00
14    NOFIMA AS NO (TROMSO) participant 150˙000.00
15    MARINE INSTITUTE IE (GALWAY) participant 118˙808.00
16    NATIONAL UNIVERSITY OF IRELAND GALWAY IE (Galway) participant 116˙058.00
17    THE QUEEN'S UNIVERSITY OF BELFAST UK (BELFAST) participant 99˙966.00
18    HAVFORSKNINGSINSTITUTTET NO (BERGEN) participant 81˙250.00
19    ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG DE (BREMERHAVEN) participant 80˙000.00
20    DANMARKS TEKNISKE UNIVERSITET DK (KGS LYNGBY) participant 78˙468.00
21    THE UNIVERSITY OF LIVERPOOL UK (LIVERPOOL) participant 29˙995.00

Map

 Project objective

The overarching goal of VIVALDI is to increase the sustainability and competitiveness of the European shellfish industry by improving the understanding of bivalve diseases and by developing innovative solutions and tools for the prevention, control and mitigation of the major pathogens affecting the main European farmed shellfish species: Pacific oyster (Crassostrea gigas), mussels (Mytilus edulis and M. galloprovincialis), European flat oyster (Ostrea edulis), clams (Venerupis philipinarum) and scallops (Pecten maximus ). The project addresses the most harmful pathogens affecting either one or more of these shellfish species: the virus OsHV-1, Vibrio species including V. aestuarianus, V. splendidus, V. harveyi and V. tapetis, as well as the parasite Bonamia ostreae. The project is committed to provide practical solutions based on the most advanced knowledge.

VIVALDI will dissect the disease mechanisms associated with pathogen virulence and pathogenesis and host immune responses, develop in vivo and in vitro models, and apply “omic” approaches that will help the development of diagnostic tools and drugs against pathogen targets, and breeding programmes in a collaborative effort with industrial partners. The proposal will include a global shellfish health approach, recognising that cultured bivalves are often exposed to several pathogens simultaneously, and that disease outbreaks can be due to the combined effect of two or more pathogens. The proposal will also investigate advantages and risks of the used of disease-resistant selected animals in order to improve consumer confidence and safety.

VIVALDI will be both multi- and trans-disciplinary. In order to cover both basic and applied levels from molecules to farm, the proposal will integrate partners with a broad range of complementary expertises in pathology and animal health, epidemiology, immunology, molecular biology, genetics, genomics and food safety.

 Deliverables

List of deliverables.
Characterisation of OsHV-1 and variants and determining their pathogenicity Documents, reports 2019-10-29 14:57:35
Effect of the interaction vibrio/plankton on the vibrio virulence Documents, reports 2019-10-29 14:57:32
Identification of the most relevant pathways in the host response obtained by bioinformatics analysis Documents, reports 2019-10-29 14:57:46
Distribution and lesions of several pathogens in oysters, mussels and clams Documents, reports 2019-10-29 14:57:30
Effect of plankton on the intake of vibrios and the outcome of the disease Documents, reports 2019-10-29 14:57:35
Press releases Websites, patent fillings, videos etc. 2019-10-29 14:57:48
Characterisation of patho-biome and description of pathogen diversity and virulence traits Documents, reports 2019-10-29 14:57:42
Selection and qPCR validation of candidate resistance markers Documents, reports 2019-10-29 14:57:30
User guide to risk ranking model and Development of risk ranking model Documents, reports 2019-10-29 14:57:47
DNA methylation profile description in oysters and mussels Documents, reports 2019-10-29 14:57:54
Website available Websites, patent fillings, videos etc. 2019-10-02 09:49:12
Stakeholder identification map for participating EU and third countries Documents, reports 2019-10-02 09:49:12

Take a look to the deliverables list in detail:  detailed list of VIVALDI deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Etienne Robino, Aurore C. Poirier, Hajar Amraoui, Sandra Le Bissonnais, Angélique Perret, Carmen Lopez‐Joven, Jean‐Christophe Auguet, Tristan P. Rubio, Chantal Cazevieille, Jean‐Luc Rolland, Yann Héchard, Delphine Destoumieux‐Garzón, Guillaume M. Charrière
Resistance of the oyster pathogen Vibrio tasmaniensis LGP32 against grazing by Vannella sp. marine amoeba involves Vsm and CopA virulence factors
published pages: , ISSN: 1462-2912, DOI: 10.1111/1462-2920.14770
Environmental Microbiology 2020-03-05
2019 Alejandro Romero, Raquel Aranguren, Rebeca Moreira, Beatriz Novoa, Antonio Figueras
Integrated transcriptomic and functional immunological approach for assessing the invasiveness of bivalve alien species
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-019-56421-y
Scientific Reports 9/1 2020-03-05
2019 Rosani, Domeneghetti, Maso, Wegner, Venier
An Evolutionary Perspective of Dopachrome Tautomerase Enzymes in Metazoans
published pages: 495, ISSN: 2073-4425, DOI: 10.3390/genes10070495
Genes 10/7 2020-03-05
2019 Aide Lasa, Andrea di Cesare, Giovanni Tassistro, Alessio Borello, Stefano Gualdi, Dolors Furones, Noelia Carrasco, Deborah Cheslett, Amanda Brechon, Christine Paillard, Adeline Bidault, Fabrice Pernet, Laura Canesi, Paolo Edomi, Alberto Pallavicini, Carla Pruzzo, Luigi Vezzulli
Dynamics of the Pacific oyster pathobiota during mortality episodes in Europe assessed by 16S rRNA gene profiling and a new target enrichment next‐generation sequencing strategy
published pages: 4548-4562, ISSN: 1462-2912, DOI: 10.1111/1462-2920.14750
Environmental Microbiology 21/12 2020-03-05
2019 Yuki Fujii, Marco Gerdol, Sarkar M. A. Kawsar, Imtiaj Hasan, Francesca Spazzali, Tatsusada Yoshida, Yukiko Ogawa, Sultana Rajia, Kenichi Kamata, Yasuhiro Koide, Shigeki Sugawara, Masahiro Hosono, Jeremy R. H. Tame, Hideaki Fujita, Alberto Pallavicini, Yasuhiro Ozeki
A GM1b/asialo‐GM1 oligosaccharide‐binding R‐type lectin from purplish bifurcate mussels Mytilisepta virgata and its effect on MAP kinases
published pages: , ISSN: 1742-464X, DOI: 10.1111/febs.15154
The FEBS Journal 2020-03-05
2019 Magalí Rey-Campos, Rebeca Moreira, Marco Gerdol, Alberto Pallavicini, Beatriz Novoa, Antonio Figueras
Immune Tolerance in Mytilus galloprovincialis Hemocytes After Repeated Contact With Vibrio splendidus
published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2019.01894
Frontiers in Immunology 10 2020-03-05
2020 Anna Toldrà, M. Dolors Furones, Ciara K. O\'Sullivan, Mònica Campàs
Detection of isothermally amplified ostreid herpesvirus 1 DNA in Pacific oyster (Crassostrea gigas) using a miniaturised electrochemical biosensor
published pages: 120308, ISSN: 0039-9140, DOI: 10.1016/j.talanta.2019.120308
Talanta 207 2020-03-05
2020 Magalí Rey-Campos, Rebeca Moreira, Alejandro Romero, Regla M. Medina-Gali, Beatriz Novoa, María Gasset, Antonio Figueras
Transcriptomic Analysis Reveals the Wound Healing Activity of Mussel Myticin C
published pages: 133, ISSN: 2218-273X, DOI: 10.3390/biom10010133
Biomolecules 10/1 2020-03-05
2020 Samuele Greco, Marco Gerdol, Paolo Edomi, Alberto Pallavicini
Molecular Diversity of Mytilin-Like Defense Peptides in Mytilidae (Mollusca, Bivalvia)
published pages: 37, ISSN: 2079-6382, DOI: 10.3390/antibiotics9010037
Antibiotics 9/1 2020-03-05
2019 Marco Gerdol, Samuele Greco, Alberto Pallavicini
Extensive Tandem Duplication Events Drive the Expansion of the C1q-Domain-Containing Gene Family in Bivalves
published pages: 583, ISSN: 1660-3397, DOI: 10.3390/md17100583
Marine Drugs 17/10 2020-03-05
2020 Alejandro Romero, Beatriz Novoa, Antonio Figueras
Extracellular traps (ETosis) can be activated through NADPH-dependent and -independent mechanisms in bivalve mollusks
published pages: 103585, ISSN: 0145-305X, DOI: 10.1016/j.dci.2019.103585
Developmental & Comparative Immunology 106 2020-03-05
2019 Antonio Figueras, Rebeca Moreira, Marta Sendra, Beatriz Novoa
Genomics and immunity of the Mediterranean mussel Mytilus galloprovincialis in a changing environment
published pages: 440-445, ISSN: 1050-4648, DOI: 10.1016/j.fsi.2019.04.064
Fish & Shellfish Immunology 90 2020-03-05
2019 Camille Clerissi, Julien de Lorgeril, Bruno Petton, Aude Lucasson, Jean-Michel Escoubas, Yannick Gueguen, Lionel Dégremont, Guillaume Mitta, Eve Toulza
Diversity and stability of microbiota are key factors associated to healthy and diseased Crassostrea gigas oysters
published pages: , ISSN: , DOI: 10.1101/378125
BioRxiv 2020-03-05
2016 Imtiaj Hasan, Marco Gerdol, Yuki Fujii, Sultana Rajia, Yasuhiro Koide, Daiki Yamamoto, Sarkar Kawsar, Yasuhiro Ozeki
cDNA and Gene Structure of MytiLec-1, A Bacteriostatic R-Type Lectin from the Mediterranean Mussel (Mytilus galloprovincialis)
published pages: 92, ISSN: 1660-3397, DOI: 10.3390/md14050092
Marine Drugs 14/5 2020-03-05
2019 Tristan Rubio, Daniel Oyanedel, Yannick Labreuche, Eve Toulza, Xing Luo, Maxime Bruto, Cristian Chaparro, Marta Torres, Julien de Lorgeril, Philippe Haffner, Jeremie Vidal-Dupiol, Arnaud Lagorce, Bruno Petton, Guillaume Mitta, Annick Jacq, Frédérique Le Roux, Guillaume M. Charrière, Delphine Destoumieux-Garzón
Species-specific mechanisms of cytotoxicity toward immune cells determine the successful outcome of Vibrio infections
published pages: 14238-14247, ISSN: 0027-8424, DOI: 10.1073/pnas.1905747116
Proceedings of the National Academy of Sciences 116/28 2020-03-05
2018 Lizenn Delisle, Bruno Petton, Jean François Burguin, Benjamin Morga, Charlotte Corporeau, Fabrice Pernet
Temperature modulate disease susceptibility of the Pacific oyster Crassostrea gigas and virulence of the Ostreid herpesvirus type 1
published pages: 71-79, ISSN: 1050-4648, DOI: 10.1016/j.fsi.2018.05.056
Fish & Shellfish Immunology 80 2019-10-02
2018 Leila Parizadeh, Delphine Tourbiez, Céline Garcia, Philippe Haffner, Lionel Dégremont, Frédérique Le Roux, Marie-Agnès Travers
Ecologically realistic model of infection for exploring the host damage caused by Vibrio aestuarianus
published pages: , ISSN: 1462-2912, DOI: 10.1111/1462-2920.14350
Environmental Microbiology 2019-10-02
2017 Patricia Cavelier, Julien Cau, Nathalie Morin, Claude Delsert
Early gametogenesis in the Pacific oyster: new insights using stem cell and mitotic markers
published pages: 3988-3996, ISSN: 0022-0949, DOI: 10.1242/jeb.167734
The Journal of Experimental Biology 220/21 2019-10-02
2018 Irene Cano, Ronny van Aerle, Stuart Ross, David W. Verner-Jeffreys, Richard K. Paley, Georgina S. E. Rimmer, David Ryder, Patrick Hooper, David Stone, Stephen W. Feist
Molecular Characterization of an Endozoicomonas -Like Organism Causing Infection in the King Scallop ( Pecten maximus L.)
published pages: , ISSN: 0099-2240, DOI: 10.1128/AEM.00952-17
Applied and Environmental Microbiology 84/3 2019-10-02
2018 Chris Rodgers, Isabelle Arzul, Noèlia Carrasco, Dolores Furones Nozal
A literature review as an aid to identify strategies for mitigating ostreid herpesvirus 1 in Crassostrea gigas hatchery and nursery systems
published pages: , ISSN: 1753-5123, DOI: 10.1111/raq.12246
Reviews in Aquaculture 2019-10-02
2018 Miriam Abbadi, Gianpiero Zamperin, Michele Gastaldelli, Francesco Pascoli, Umberto Rosani, Adelaide Milani, Alessia Schivo, Emanuele Rossetti, Edoardo Turolla, Lorenzo Gennari, Anna Toffan, Giuseppe Arcangeli, Paola Venier
Identification of a newly described OsHV-1 µvar from the North Adriatic Sea (Italy)
published pages: 693-703, ISSN: 0022-1317, DOI: 10.1099/jgv.0.001042
Journal of General Virology 99/5 2019-10-02
2018 Luigi Vezzulli, L. Stagnaro, C. Grande, G. Tassistro, L. Canesi, C. Pruzzo
Comparative 16SrDNA Gene-Based Microbiota Profiles of the Pacific Oyster (Crassostrea gigas) and the Mediterranean Mussel (Mytilus galloprovincialis) from a Shellfish Farm (Ligurian Sea, Italy)
published pages: 495-504, ISSN: 0095-3628, DOI: 10.1007/s00248-017-1051-6
Microbial Ecology 75/2 2019-10-02
2019 Manon Auguste, Aide Lasa, Alberto Pallavicini, Stefano Gualdi, Luigi Vezzulli, Laura Canesi
Exposure to TiO2 nanoparticles induces shifts in the microbiota composition of Mytilus galloprovincialis hemolymph
published pages: 129-137, ISSN: 0048-9697, DOI: 10.1016/j.scitotenv.2019.03.133
Science of The Total Environment 670 2019-10-02
2019 Sandy Picot, Benjamin Morga, Nicole Faury, Bruno Chollet, Lionel Dégremont, Marie-Agnès Travers, Tristan Renault, Isabelle Arzul
A study of autophagy in hemocytes of the Pacific oyster, Crassostrea gigas
published pages: 1-9, ISSN: 1554-8627, DOI: 10.1080/15548627.2019.1596490
Autophagy 2019-10-02
2019 Magalí Rey-Campos, Rebeca Moreira, Valentina Valenzuela-Muñoz, Cristian Gallardo-Escárate, Beatriz Novoa, Antonio Figueras
High individual variability in the transcriptomic response of Mediterranean mussels to Vibrio reveals the involvement of myticins in tissue injury
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-019-39870-3
Scientific Reports 9/1 2019-10-02
2017 Gerdol, Marco
Immune-related genes in gastropods and bivalves: a comparative overview
published pages: , ISSN: 1824-307X, DOI:
Invertebrate Survival Journal 1 2019-10-02
2018 Teresa Balbi, Katia Cortese, Caterina Ciacci, Grazia Bellese, Luigi Vezzulli, Carla Pruzzo, Laura Canesi
Autophagic processes in Mytilus galloprovincialis hemocytes: Effects of Vibrio tapetis
published pages: 66-74, ISSN: 1050-4648, DOI: 10.1016/j.fsi.2017.12.003
Fish & Shellfish Immunology 73 2019-10-02
2019 GM Ward, SW Feist, P Noguera, M Marcos-López, S Ross, M Green, A Urrutia, D Bass
Detection and characterisation of haplosporidian parasites of the blue mussel Mytilus edulis, including description of the novel parasite Minchinia mytili n. sp.
published pages: 57-68, ISSN: 0177-5103, DOI: 10.3354/dao03326
Diseases of Aquatic Organisms 133/1 2019-10-02
2018 Rebeca Moreira, Pablo Balseiro, Gabriel Forn-Cuní, Massimo Milan, Luca Bargelloni, Beatriz Novoa, Antonio Figueras
Bivalve transcriptomics reveal pathogen sequences and a powerful immune response of the Mediterranean mussel (Mytilus galloprovincialis)
published pages: , ISSN: 0025-3162, DOI: 10.1007/s00227-018-3308-0
Marine Biology 165/4 2019-10-02
2018 Anna Toldrà, Karl B. Andree, Edgar Bertomeu, Ana Roque, Noèlia Carrasco, Ignasi Gairín, M. Dolores Furones, Mònica Campàs
Rapid capture and detection of ostreid herpesvirus-1 from Pacific oyster Crassostrea gigas and seawater using magnetic beads
published pages: e0205207, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0205207
PLOS ONE 13/10 2019-10-02
2018 Julien de Lorgeril, Aude Lucasson, Bruno Petton, Eve Toulza, Caroline Montagnani, Camille Clerissi, Jeremie Vidal-Dupiol, Cristian Chaparro, Richard Galinier, Jean-Michel Escoubas, Philippe Haffner, Lionel Dégremont, Guillaume M. Charrière, Maxime Lafont, Abigaïl Delort, Agnès Vergnes, Marlène Chiarello, Nicole Faury, Tristan Rubio, Marc A. Leroy, Adeline Pérignon, Denis Régler, Benjamin Morga, Marianne Alunno-Bruscia, Pierre Boudry, Frédérique Le Roux, Delphine Destoumieux-Garzόn, Yannick Gueguen, Guillaume Mitta
Immune-suppression by OsHV-1 viral infection causes fatal bacteraemia in Pacific oysters
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-06659-3
Nature Communications 9/1 2019-10-02
2018 Carmen Lopez-Joven, Jean-Luc Rolland, Philippe Haffner, Audrey Caro, Cécile Roques, Claire Carré, Marie-Agnès Travers, Eric Abadie, Mohamed Laabir, Delphine Bonnet, Delphine Destoumieux-Garzón
Oyster Farming, Temperature, and Plankton Influence the Dynamics of Pathogenic Vibrios in the Thau Lagoon
published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2018.02530
Frontiers in Microbiology 9 2019-10-02

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