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Crossover control

New insights into wheat meiosis: Crossover resolution in the absence of the Ph1 locus

Total Cost €


EC-Contrib. €






Project "Crossover control" data sheet

The following table provides information about the project.


Organization address
postcode: NR4 7UH

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-03-01   to  2018-02-28


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    JOHN INNES CENTRE UK (NORWICH) coordinator 183˙454.00


 Project objective

This project ultimately aims to increase the crossover frequency in bread wheat (T. aestivum), which would result in a higher number of recombination events and would be a powerful tool for plant breeding. Thus the results of the proposed research are relevant to crop improvement as well as to human health. In the next 50 years, we will require as much wheat as has been produced since the beginning of agriculture. There are 1.5 billion dependent poor in the world, of which 300 million living in countries surrounding Europe are at risk of starvation in the future. Finding solutions to address the problems of wheat production will be a dominant topic in European plant science.

Specifically, this project builds on the work of the host group on the Ph1 locus - the major wheat locus controlling the specificity of chromosome pairing and recombination, and which ensures high fertility. Future breeding strategies for wheat will require exploitation of diversity in wild relatives, and manipulation of the Ph1 locus will be a powerful tool to facilitate introgression of traits from these related species. Recent work in the host group has shown that Ph1 locus carries cdk2-like kinases, and that deletion of Ph1 increases protein phosphorylation levels, altering the homologue pairing specificity. A major objective of this project is to characterise the alterations in the phospho-proteome of the meiocytes that result from deletion of the Ph1 locus. Recent results from a group studying meiosis in C. elegans have also shown that meiotic pairing specificity and recombination depend on protein phosphorylation levels, suggesting that the mechanism underlying Ph1 may be quite general. During this project we will collaborate with the C. elegans researchers to explore the similarities between the two kingdoms.


year authors and title journal last update
List of publications.
2017 María-Dolores Rey, Azahara C. Martín, Janet Higgins, David Swarbreck, Cristobal Uauy, Peter Shaw, Graham Moore
Exploiting the ZIP4 homologue within the wheat Ph1 locus has identified two lines exhibiting homoeologous crossover in wheat-wild relative hybrids
published pages: , ISSN: 1380-3743, DOI: 10.1007/s11032-017-0700-2
Molecular Breeding 37/8 2019-06-13
2018 Maria-Dolores Rey, Azahara Carmen Martin, Mark Smedley, Sadiye Hayta, Wendy Harwood, Peter Shaw, Graham Moore
Magnesium increases homoeologous crossover frequency in ZIP4 (Ph1) mutant wheat-wild relative hybrids
published pages: , ISSN: , DOI: 10.3389/fpls.2018.00509
2018 Amy Watson, Sreya Ghosh, Matthew J. Williams, William S. Cuddy, James Simmonds, María-Dolores Rey, M. Asyraf Md Hatta, Alison Hinchliffe, Andrew Steed, Daniel Reynolds, Nikolai M. Adamski, Andy Breakspear, Andrey Korolev, Tracey Rayner, Laura E. Dixon, Adnan Riaz, William Martin, Merrill Ryan, David Edwards, Jacqueline Batley, Harsh Raman, Jeremy Carter, Christian Rogers, Claire Domoney, Graham Moore, Wendy Harwood, Paul Nicholson, Mark J. Dieters, Ian H. DeLacy, Ji Zhou, Cristobal Uauy, Scott A. Boden, Robert F. Park, Brande B. H. Wulff, Lee T. Hickey
Speed breeding is a powerful tool to accelerate crop research and breeding
published pages: 23-29, ISSN: 2055-0278, DOI: 10.1038/s41477-017-0083-8
Nature Plants 4/1 2019-06-13

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The information about "CROSSOVER CONTROL" are provided by the European Opendata Portal: CORDIS opendata.

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