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Guide Stars Adaptive Optics for Retinal Imaging

Total Cost €


EC-Contrib. €






Project "GSAORI" data sheet

The following table provides information about the project.


Organization address
address: SPITALGASSE 23
city: WIEN
postcode: 1090

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Project website
 Total cost 166˙156 €
 EC max contribution 166˙156 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-04-01   to  2018-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MEDIZINISCHE UNIVERSITAET WIEN AT (WIEN) coordinator 166˙156.00


 Project objective

The Guide Stars Adaptive Optics for Retinal Imaging (GSAORI) project aims at developing new imaging techniques in the field of ophthalmology. As the eye presents time-variable aberrations, an Adaptive Optics (AO) loop greatly enhances quality and resolution of retinal imaging, enabling the examination of structures such as cone and rod photoreceptors and leukocytes in vivo in a non invasive way and at a microscopic scale. Although AO has enabled outstanding progresses in ophthalmology, it has its limitation. The pupil motion and tear film thickness changes during the examination can limit the performance of the AO system. Also, the distortions of the retinal structure influence the wave-front analysis. Finally motion artefacts can have a strong impact on the correction capacity of the AO system. Therefore satisfactory image quality can only be achieved in carefully selected patients, which currently prevents a widespread use of this technology. The overall objective of the project is to overcome these limitations by developing systems that are more robust to retinal distortions and local media opacities. This will enable acceptable image quality in the majority of patients. The emergence of versatile AO systems would be a significant milestone towards making this technique a routine for eye examination. To achieve this goal, we propose to use guide stars that are spread over different locations of the retina to minimize the influence of eye’s defects on the wave-front measurements. This technique is directly inspired from astronomical telescopes where several laser guide stars are used as references to provide efficient wave-front correction on a large field of view. Following the conception of a system with guide stars, new algorithms for wave-front sensing and control will be developed, providing a fully functional innovative AO system. To fulfil its objectives, the research project will be based on extensive system modelling, and on in-vivo eyes’ measurements.


year authors and title journal last update
List of publications.
2017 Marie Laslandes, Matthias Salas, Christoph K. Hitzenberger, Michael Pircher
Optimizing the sampling density of a wave-front sensor in adaptive optics systems: application to scanning laser ophthalmoscopy
published pages: 1007318, ISSN: , DOI: 10.1117/12.2250732
Adaptive Optics and Wavefront Control for Biological Systems III 2019-06-13
2017 Marie Laslandes, Matthias Salas, Christoph K. Hitzenberger, Michael Pircher
Influence of wave-front sampling in adaptive optics retinal imaging
published pages: 1083, ISSN: 2156-7085, DOI: 10.1364/BOE.8.001083
Biomedical Optics Express 8/2 2019-06-13
2017 Andreas Wartak, Marco Augustin, Richard Haindl, Florian Beer, Matthias Salas, Marie Laslandes, Bernhard Baumann, Michael Pircher, Christoph K. Hitzenberger
Multi-directional optical coherence tomography for retinal imaging
published pages: 5560, ISSN: 2156-7085, DOI: 10.1364/boe.8.005560
Biomedical Optics Express 8/12 2019-06-13
2017 Marie Laslandes, Matthias Salas, Christoph K. Hitzenberger, Michael Pircher
Increasing the field of view of adaptive optics scanning laser ophthalmoscopy
published pages: 4811, ISSN: 2156-7085, DOI: 10.1364/BOE.8.004811
Biomedical Optics Express 8/11 2019-06-13

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The information about "GSAORI" are provided by the European Opendata Portal: CORDIS opendata.

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