Opendata, web and dolomites

PELIG

Characterisation of a Novel Pathway for Lignin Fragment Degradation in Rhodococcus jostii

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "PELIG" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF WARWICK 

Organization address
address: Kirby Corner Road - University House
city: COVENTRY
postcode: CV4 8UW
website: www.warwick.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website https://warwick.ac.uk/fac/sci/chemistry/research/bugg/bugggroup/
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-10-06   to  2018-10-05

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF WARWICK UK (COVENTRY) coordinator 183˙454.00

Map

 Project objective

Lignin, composed of phenylpropanoic units, represents an attractive raw material for renewable aromatic chemicals. Lignin valorisation instead of petrochemical industry for chemicals production is a hot research area in green chemistry. Microorganisms have been proven to evolve metabolic pathways that enable the break-down of lignin; however, this lignin-to-chemicals bioconversion by both fungi and bacteria lacks essential attributes to commercial implementation. In the forefront, “omics” research has pointed out potential target genes and enzymes for manipulation, leading to more applied lignin bioconversion studies. Bacterial lignin metabolism is attracting more attention due to its relatively simple protein expression and genetic modification compared to fungi, which provides a potential application of a targeted pathway engineering strategy for diversified lignin-derived byproducts accumulation and yield enhancement. Hence, the discovery of unknown lignin metabolic pathways and gene products in bacteria is of importance. In this context, the current proposed research will explore and manipulate a novel lignin metabolic pathway - transketolase lignin degradation pathway - in Rhodococcus for lignin-based renewable chemicals production by using a synthetic biology approach. The goal will be achieved by pursuing the following two objectives: 1) elucidation and characterization of the novel enzyme encoded with tklX and evaluation of its activity reacted with lignin model compounds as transketolase; 2) targeted gene deletion for pathway engineering in genetically tractable hosts to manipulate lignin breakdown. The results of this study will therefore establish a promising foundation for production of lignin-derived chemicals from renewable feedstocks via catabolic pathways. Meanwhile, the Action will clearly provide the Applicant with unique opportunities to reach a position of professional maturity.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PELIG" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PELIG" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

NaWaTL (2020)

Narrative, Writing, and the Teotihuacan Language: Exploring Language History Through Phylogenetics, Epigraphy and Iconography

Read More  

KOMODOH (2020)

From molecules to communities: unraveling ecological drivers of interactions between oaks and their insect herbivores

Read More  

MathematicsAnalogies (2019)

Mathematics Analogies

Read More