Opendata, web and dolomites

GENDER-CF

Gender-related differences in expression of microRNAs in cystic fibrosis

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 GENDER-CF project word cloud

Explore the words cloud of the GENDER-CF project. It provides you a very rough idea of what is the project "GENDER-CF" about.

mirnas    qpcr    sex    genes    innovative    flow    college    team    statistically    skills    progression    immunity    pi    acquisition    inflammatory    consequent    secondments    traf6    microrna    cystic    gap    function    cornerstone    student    network    form    expression    fellowship    pulmonary    ireland    females    defective    encoding    disease    implicated    aid    career    inflammation    applicable    engagement    predicted    gender    combine    class    morbidity    therapies    public    competencies    cell    survival    regulation    receptor    strengthen    host    leiden    tlr4    expand    patients    rcsi    professionally    equipped    noted    royal    diversify    immunology    heidelberg    position    centre    progressive    tumour    epithelial    lung    renowned    medical    plays    ing    exacerbations    independence    netherlands    laboratory    hormone    collaborative    toll    respiratory    university    death    estrogen    mediators    ongoing    accelerating    germany    keen    necrosis    mirna    female    expertise    am    hereditary    ion    cytometry    richly    transferable    teams    airway    channel    cf    infective    data    surgeons    world    supervision    disadvantage    innate    altered    active    fibrosis   

Project "GENDER-CF" data sheet

The following table provides information about the project.

Coordinator
ROYAL COLLEGE OF SURGEONS IN IRELAND 

Organization address
address: Saint Stephen's Green 123
city: DUBLIN
postcode: 2
website: www.rcsi.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Project website https://www.researchgate.net/project/Gender-related-differences-in-expression-of-microRNAs-in-cystic-fibrosis
 Total cost 175˙866 €
 EC max contribution 175˙866 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2019-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ROYAL COLLEGE OF SURGEONS IN IRELAND IE (DUBLIN) coordinator 175˙866.00

Map

 Project objective

Cystic fibrosis (CF) is a hereditary disease involving a defective ion channel, resulting in altered epithelial cell function and consequent infective/inflammatory airway exacerbations. Progressive loss of lung function is the leading cause of death in CF patients. It is statistically noted that females have a disadvantage in survival and morbidity; this is commonly referred to as the CF gender gap. Recent studies have implicated the female sex hormone, estrogen, in this gender gap. CF patients show altered microRNA expression and some of the affected miRNAs are predicted to target genes encoding key inflammatory mediators such as Toll-like receptor 4 (TLR4) and tumour necrosis factor a receptor associated factor-6 (TRAF6). This highly innovative proposal, to be implemented at the Royal College of Surgeons Ireland (RCSI), aims to study the regulation of key miRNAs by estrogen and investigate if this plays a role in the CF gender gap. I will combine my own expertise in pulmonary innate immunity with the host PI’s world-class knowledge of CF and miRNA research. The research will further our understanding of inflammation in CF to aid development of better therapies. I will develop professionally as I: a) diversify my competencies through the acquisition of new laboratory skills (e.g. qPCR, flow cytometry), b) strengthen my transferable skills (e.g. project management, public engagement, data dissemination) and c) expand my collaborative network through secondments to other world-renowned research teams in Leiden University Medical Centre, Netherlands and University of Heidelberg, Germany. I will contribute richly to research at RCSI as I am already equipped with skills applicable to ongoing work in the team and am keen to take an active role in student supervision. The opportunities carried by this fellowship will form the cornerstone of my career, accelerating my progression towards my goal of achieving a position of independence in respiratory immunology research.

 Publications

year authors and title journal last update
List of publications.
2018 Arlene M.A. Glasgow, Chiara De Santi, Catherine M. Greene
Non-coding RNA in cystic fibrosis
published pages: 619-630, ISSN: 0300-5127, DOI: 10.1042/bst20170469
Biochemical Society Transactions 46/3 2020-01-29

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "GENDER-CF" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "GENDER-CF" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

CORRELATION (2020)

Characterization and prediction of service-level traffic for future sliced mobile network

Read More  

Photonic Radar (2019)

Implementation of Long Reach Hybrid Photonic Radar System and convergence over FSO and PON Networks

Read More  

ASIQS (2019)

Antiferromagnetic spintronics investigated by quantum sensing techniques

Read More