Opendata, web and dolomites

MemoryDynamics SIGNED

Writing and editing of memories from acquisition to long-term consolidation

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "MemoryDynamics" data sheet

The following table provides information about the project.

Coordinator
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION 

Organization address
address: MAULBEERSTRASSE 66
city: BASEL
postcode: 4058
website: www.fmi.ch

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 2˙499˙604 €
 EC max contribution 2˙499˙604 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-AdG
 Funding Scheme ERC-ADG
 Starting year 2016
 Duration (year-month-day) from 2016-10-01   to  2021-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION CH (BASEL) coordinator 2˙499˙604.00

Map

 Project objective

Nervous systems produce adaptive behavior, arguably their most important function, through learning and memory. Memories ensure that what is learned will be available for later retrieval. Upon the initial learning process, synaptic plasticity important for memory consolidation is triggered within minutes, but whether, and in which form memories will be retained more permanently can be influenced by information and insights gained after the initial trigger. Learning and memory have been studied extensively, but we still know very little about the mechanisms through which memories are shaped after acquisition. Here we hypothesize that instead of simply reflecting requirements to produce long-term memory traces, cascades of plasticity processes induced at the time of acquisition might also reflect systems requirements for updating of new relevant information, as well as selection of potentially useful memories that need to enter the process of long-term consolidation.

Recent advances in neuroscience have provided powerful novel means to reveal, analyze and manipulate memory traces in the living brain, from single neurons to systems, and to interrogate their function. This research program will address the functional roles of learning-related plasticity processes unfolding subsequent to acquisition in learning and memory. We will investigate how hippocampal memories are shaped during several hours after acquisition through network activity and addition of new information through experience, and how these processes involve unique roles for dorsal hippocampus, and for dedicated neuronal circuits. Furthermore, we will study how shaped memories are then long-term consolidated, including the key role of ventral hippocampal circuitry, and how memories are further modified through subsequent learning. This research will produce fundamentally novel insights into how learning leads to adaptive behavior through writing and editing of memories.

 Publications

year authors and title journal last update
List of publications.
2018 Matteo Tripodi, Komal Bhandari, Ananya Chowdhury, Arghya Mukherjee, Pico Caroni
Parvalbumin Interneuron Plasticity for Consolidation of Reinforced Learning
published pages: 25-35, ISSN: 0091-7451, DOI: 10.1101/sqb.2018.83.037630
Cold Spring Harbor Symposia on Quantitative Biology 83 2019-12-16
2019 Arghya Mukherjee, Fernando Carvalho, Stephan Eliez, Pico Caroni
Long-Lasting Rescue of Network and Cognitive Dysfunction in a Genetic Schizophrenia Model
published pages: 1387-1402.e14, ISSN: 0092-8674, DOI: 10.1016/j.cell.2019.07.023
Cell 178/6 2019-12-16
2019 Sebastian Krüttner, Pico Caroni
m6A-epitranscriptome modulates memory strength
published pages: 4-5, ISSN: 1001-0602, DOI: 10.1038/s41422-018-0121-8
Cell Research 29/1 2019-06-07
2018 Ananya Chowdhury, Pico Caroni
Time units for learning involving maintenance of system-wide cFos expression in neuronal assemblies
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-06516-3
Nature Communications 9/1 2019-06-07
2018 Arghya Mukherjee, Pico Caroni
Infralimbic cortex is required for learning alternatives to prelimbic promoted associations through reciprocal connectivity
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-05318-x
Nature Communications 9/1 2019-06-07

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MEMORYDYNAMICS" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MEMORYDYNAMICS" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

iNANOVAC4CANCER (2019)

BIOHYBRID AND BIODEGRADABLE NANOVACCINES FOR CANCER IMMUNOTHERAPY

Read More  

VictPart (2019)

Righting Victim Participation in Transitional Justice

Read More  

SuperH (2019)

Discovery and Characterization of Hydrogen-Based High-Temperature Superconductors

Read More