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BEND

Bendable Bioplatform for Electrically stimulated Neuronal Differentiation

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EC-Contrib. €

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Project "BEND" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF GLASGOW 

Organization address
address: UNIVERSITY AVENUE
city: GLASGOW
postcode: G12 8QQ
website: www.gla.ac.uk

contact info
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name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
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 Coordinator Country United Kingdom [UK]
 Project website https://ec.europa.eu/research/participants/grants-app/reporting/REP-704807-1/PeriodicReportForm/technical
 Total cost 195˙454 €
 EC max contribution 195˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-08-15   to  2018-08-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF GLASGOW UK (GLASGOW) coordinator 195˙454.00

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 Project objective

Summary of Marie Curie Proposal for H2020-MSCA-IF-2015

“Bendable Bioplatform for Electrically stimulated Neuronal Differentiation”

With western countries aging faster, the neurodegenerative diseases like Parkinson’s, Alzheimer’s, Huntington’s etc. pose serious threat to quality of life, especially for people over 65 years[1]. In Europe, number of people suffering with dementia, which results from neuronal degeneration, is on the rise it is expected to be double in the next 20 Years[2]. The neuronal degeneration is irreversible[3] and currently the cell therapy for regeneration of neuron network is the only option to compensate such a loss. Recently, the induced pluripotent stem cell (iPSC) derived NSC therapy has come up as an excellent opportunity in treating of neuro degenerative diseases. However, proliferation and differentiation of iPS cell population in neuronal replacement therapies poses many technical challenges such as targeted neurite differentiation to compensate desired loss with controlled differentiation[4]. Traditionally, the neuronal differentiation of iPSC is performed using several transcriptional and growth factors, which are complex, expensive and non-scalable processes[5]. For this reason, the research for a simple, robust and scalable method for generating large number of mature, differentiated neuronal cell deserves top priority. In addition, an accurate on/off system for scalable proliferation and neuronal differentiation is pivotal for the development of implantable bioelectronics circuit suitable for in vivo application. It is believed that the electrical stimulus controlled neuronal differentiation of stem cells on a soft, bendable electro conductive substrate can be suitable for bioelectronics application and also for compensating neuronal loss in the degenerative disease or injuries. This project is an ambitious endeavour in this direction. A bendable bioplatform will be developed for electrically stimulated neural differentiation t

 Publications

year authors and title journal last update
List of publications.
2019 Khudishta Aktar, Abdul Kafi, Ravinder Dahiya
Association of Gpx1 fluctuation in cell cycle progression
published pages: , ISSN: 1071-2690, DOI: 10.1007/s11626-018-00314-3
In Vitro Cellular & Developmental Biology - Animal 2019-05-10
2019 Md. Abdul Kafi; Ambarish Paul; Anastasios Vilouras; Ravinder Dahiya
Chitosan-Graphene Oxide Based Ultra-Thin Conformable Sensing Patch for Cell-Health Monitoring
published pages: , ISSN: , DOI:
2018 IEEE SENSORS 2019-05-10
2019 Anastasios Vilouras ; Ambarish Paul ; Md. Abdul Kafi ; Ravinder Dahiya
Graphene Oxide-Chitosan Based Ultra-Flexible Electrochemical Sensor for Detection of Serotonin
published pages: , ISSN: , DOI:
2018 IEEE SENSORS 2019-05-10

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