Opendata, web and dolomites

Protoeukaryotes

Multicompartmental Designs For Protocells

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 Protoeukaryotes project word cloud

Explore the words cloud of the Protoeukaryotes project. It provides you a very rough idea of what is the project "Protoeukaryotes" about.

perceived    artificial    compartment    apart    multicompartmental    stephen    progress    life    bristol    last    few    organization    perform    literature    harvesting    functions    nanochannels    programmed    regard    clinical    organelles    expertise    cellular    membrane    remote    selective    locomotion    pavan    model    complexity    replication    mimics    prof    sensing    quintessential    feedback    homeostasis    frs    compartmentalization    levels    exhibiting    kumar    polymers    hierarchical    exchange    responsive    stimuli    membranes    hosting    issue    mann    group    function    species    cells    parallel    origin    eukaryotic    interaction    metabolite    activate    smart    bound    models    protocells    self    metabolites    interacting    detoxification    exists    light    gates    university    ing    diagnosis    dr    tremendous    transport    enabled    regulation    leadership    constructing    construction    edge    broadened    networks    minimal    protocell    made    cutting    living    protocellular    structural    environment    micromachines    date    chemical    drug    disciplinary    compartments   

Project "Protoeukaryotes" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF BRISTOL 

Organization address
address: BEACON HOUSE QUEENS ROAD
city: BRISTOL
postcode: BS8 1QU
website: www.bristol.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-09-01   to  2018-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF BRISTOL UK (BRISTOL) coordinator 183˙454.00

Map

 Project objective

Protocells are artificial mimics of cellular systems exhibiting some of the quintessential characteristics of living systems such as compartmentalization, replication and selective exchange of chemical species with the environment. Apart from enabling better understanding about the origin of life, protocells can also be perceived as micromachines which can be programmed to perform functions such as clinical diagnosis, drug delivery, remote sensing, environment detoxification, etc. The range of applications for protocells can be broadened by increasing their structural complexity which would enable complex functions. However, to date the structural complexity of protocellular models has been minimal. Eukaryotic cells are model systems for complexity with compartmentalization into membrane bound organelles interacting through selective exchange of metabolites resulting in complex chemical networks which make possible smart functions such as feedback regulation and homeostasis. No parallel of this hierarchical organization exists in protocell literature. The aim of this proposal is to address this issue by design and construction of multicompartmental protocell models capable of complex functions such as self-regulation, locomotion and light harvesting. The interaction between the various compartments will be enabled by constructing gates across their membranes using stimuli responsive polymers to allow compartments to activate pathways which can affect the function or metabolite level of another compartment, leading to self-regulation of function or metabolite levels in the protocell. It is in this regard that the previous expertise of the applicant (Dr. Pavan Kumar) in constructing gates to control the transport in nanochannels will be applied to the multi-disciplinary and cutting edge field of protocells in which the hosting group at the University of Bristol (under the leadership of Prof.Stephen Mann FRS) has made tremendous progress in the last few years.

 Publications

year authors and title journal last update
List of publications.
2018 B. V. V. S. Pavan Kumar, James Fothergill, Joshua Bretherton, Liangfei Tian, Avinash J. Patil, Sean A. Davis, Stephen Mann
Chloroplast-containing coacervate micro-droplets as a step towards photosynthetically active membrane-free protocells
published pages: 3594-3597, ISSN: 1359-7345, DOI: 10.1039/C8CC01129J
Chemical Communications 54/29 2019-05-10
2018 B. V. V. S. Pavan Kumar, Avinash J. Patil, Stephen Mann
Enzyme-powered motility in buoyant organoclay/DNA protocells
published pages: 1154-1163, ISSN: 1755-4330, DOI: 10.1038/s41557-018-0119-3
Nature Chemistry 10/11 2019-05-10

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PROTOEUKARYOTES" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PROTOEUKARYOTES" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

POSPORI (2019)

Polymer Optical Sensors for Prolonged Overseeing the Robustness of civil Infrastructures

Read More  

ACES (2019)

Antarctic Cyclones: Expression in Sea Ice

Read More  

AMPLE (2019)

A Study of the Notion of Ampleness in Model Theory and Tits Buildings

Read More