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TRACT SIGNED

Training in Cancer Mechanisms and Therapeutics

Total Cost €

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EC-Contrib. €

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Partnership

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 TRACT project word cloud

Explore the words cloud of the TRACT project. It provides you a very rough idea of what is the project "TRACT" about.

collaborative    expertise    cellular    cohort    clinicians    receive    prospects    skills    imaging    translational    entire    resolution    industrial    drug    immunologists    esrs    crispr    economy    diagnostics    position    detection    countries    trained    internationally    oesophageal    screening    courses    community    cross    diagnosed    brings    isolation    technologies    diagnosis    basis    employment    complementary    tools    therapies    training    oral    treatment    resistance    patient    career    genome    metabolism    metabolite    biochemists    sequencing    exosome    commercialisation    specialised    drive    computational    private    placements    disease    entrepreneurship    cancers    insights    options    identification    cancer    therapeutics    last    survival    global    metabolomics    50    mobile    biomarker    presentation    section    enhanced    validation    75    tract    medicinal    generate    patients    interdisciplinary    generation    engagement    molecular    diagnostic    rates    chemists    public    discover    stage    medicine    chemistry   

Project "TRACT" data sheet

The following table provides information about the project.

Coordinator
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN 

Organization address
address: College Green
city: DUBLIN
postcode: 2
website: www.tcd.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Project website http://www.qub.ac.uk/sites/TraininginCancerMechanismsandTherapeutics/
 Total cost 2˙877˙076 €
 EC max contribution 2˙877˙076 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2016
 Funding Scheme MSCA-ITN-ETN
 Starting year 2016
 Duration (year-month-day) from 2016-10-01   to  2020-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN IE (DUBLIN) coordinator 1˙062˙698.00
2    THE QUEEN'S UNIVERSITY OF BELFAST UK (BELFAST) participant 546˙575.00
3    UNIVERSITA DEGLI STUDI DI SIENA IT (SIENA) participant 516˙122.00
4    UNIVERSITAT DE VALENCIA ES (VALENCIA) participant 495˙745.00
5    OROBOROS INSTRUMENTS GmbH AT (INNSBRUCK) participant 255˙934.00
6    ALMAC DIAGNOSTIC SERVICES LIMITED UK (CRAIGAVON) partner 0.00
7    ANDOR TECHNOLOGY LIMITED UK (BELFAST) partner 0.00
8    Exosomics Siena S.p.A. IT (Siena) partner 0.00
9    Fraunhofer Society DE (Munich) partner 0.00
10    NATIONAL INSTITUTE FOR BIOPROCESSING RESEARCH AND TRAINING LIMITED IE (BLACKROCK DUBLIN) partner 0.00
11    Opsona Therapeutics IE (DUBLIN) partner 0.00
12    Seahorse UK (London) partner 0.00

Map

 Project objective

The European community requires early stage researchers (ESRs) trained in next-generation technologies for improved detection and treatment of oral and oesophageal cancers. The number of oral cancers diagnosed in the EU has increased by over 75% in the last 30 years, with long-term survival rates of only 50%. This is typically due to the late diagnosis of the disease and resistance to current therapies. Through the collaborative expertise of clinicians, biochemists, immunologists, and chemists TRACT will enable ESRs to discover novel insights into the molecular and cellular basis of these cancers and generate new diagnostic tools and therapeutics that improve patient response and survival. Each Institution brings unique but complementary expertise in cancer metabolism, metabolomics, high-resolution imaging, biomarker identification, computational modelling, medicinal chemistry, target validation, drug development and translational medicine. Industrial placements in five European countries will ensure ESRs receive specialised training in the development of next-generation technologies in such areas as whole genome sequencing, CRISPR technology, drug screening, exosome isolation and analysis, cancer imaging, metabolism and metabolite analysis in addition to the unique employment experience of working in the private sector. Courses in commercialisation, project management and presentation skills will ensure ESRs will have the ability to present their results to the entire cross-section of the European community, through public engagement. TRACT will deliver a cohort of internationally mobile cancer researchers with interdisciplinary skills who will have enhanced career prospects and be in a position to have an impact on the European and global research stage by providing new technologies that can drive entrepreneurship into the European economy and improved diagnostics and treatment options for cancer patients in Europe and beyond.

 Deliverables

List of deliverables.
Recruitment strategy Documents, reports 2019-07-09 10:17:50
Dissemination diary, Year 1 Documents, reports 2019-07-09 10:17:50
ESR traning and progress year 1 Documents, reports 2019-07-09 10:17:50

Take a look to the deliverables list in detail:  detailed list of TRACT deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 VR Dikova, S Principe, JV Bagan
Salivary inflammatory proteins in patients with oral potentially malignant disorders
published pages: 0-0, ISSN: 1989-5488, DOI: 10.4317/jced.55917
Journal of Clinical and Experimental Dentistry 2020-01-30
2019 S Principe, V Dikova, J Bagan
Salivary Cytokines in patients with Head and Neck Cancer (HNC) treated with Radiotherapy
published pages: 0-0, ISSN: 1989-5488, DOI: 10.4317/jced.56318
Journal of Clinical and Experimental Dentistry 2020-01-30
2018 Stefano Federico, Tuhina Khan, Nicola Relitti, Giulia Chemi, Margherita Brindisi, Simone Brogi, Ettore Novellino, Daniela M. Zisterer, Giuseppe Campiani, Sandra Gemma, Stefania Butini
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents
published pages: 4466-4470, ISSN: 0040-4039, DOI: 10.1016/j.tetlet.2018.11.005
Tetrahedron Letters 59/51 2019-07-09
2018 Brian Flood, Joan Manils, Ciara Nulty, Ewelina Flis, Sinead Kenealy, Gillian Barber, Joanna Fay, Kingston H. G. Mills, Elaine W. Kay, Emma M. Creagh
Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis
published pages: , ISSN: 0950-9232, DOI: 10.1038/s41388-018-0613-5
Oncogene 2019-07-09
2018 Jaine K. Blayney, Lauren Cairns, Gerald Li, Niamh McCabe, Leanne Stevenson, Christopher J. Peters, Nathan B. Reid, Veronica J. Spence, Chintapuza Chisambo, Damian McManus, Jacqueline James, Stephen McQuaid, Stephanie Craig, Kenneth Arthur, Darragh McArt, Chin-Ann J. Ong, Pierre Lao-Sirieix, Peter Hamilton, Manuel Salto-Tellez, Martin Eatock, Helen G. Coleman, Rebecca C. Fitzgerald, Richard D. Kennedy, Richard C. Turkington
Glucose transporter 1 expression as a marker of prognosis in oesophageal adenocarcinoma
published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.24906
Oncotarget 9/26 2019-07-09
2019 Margherita Brindisi, Cristina Ulivieri, Gloria Alfano, Sandra Gemma, Francisco de Asís Balaguer, Tuhina Khan, Alessandro Grillo, Giulia Chemi, Grégory Menchon, Andrea E. Prota, Natacha Olieric, Daniel Lucena-Agell, Isabel Barasoain, J. Fernando Diaz, Angela Nebbioso, Mariarosaria Conte, Ludovica Lopresti, Stefania Magnano, Rebecca Amet, Paula Kinsella, Daniela M. Zisterer, Ola Ibrahim, Jeff O\'Sullivan, Lucia Morbidelli, Roberta Spaccapelo, Cosima Baldari, Stefania Butini, Ettore Novellino, Giuseppe Campiani, Lucia Altucci, Michel O. Steinmetz, Simone Brogi
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents
published pages: 290-320, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2018.11.004
European Journal of Medicinal Chemistry 162 2019-07-09

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