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npSCOPE SIGNED

The nanoparticle-scope : a new integrated instrument for accurate and reproducible physico-chemical characterisation of nanoparticles (npSCOPE)

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EC-Contrib. €

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Partnership

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Project "npSCOPE" data sheet

The following table provides information about the project.

Coordinator
LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY 

Organization address
address: 5 AVENUE DES HAUTS FOURNEAUX
city: ESCH SUR ALZETTE
postcode: 4362
website: www.list.lu

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Luxembourg [LU]
 Project website http://www.npscope.eu/
 Total cost 7˙487˙475 €
 EC max contribution 6˙661˙600 € (89%)
 Programme 1. H2020-EU.2.1.2.2. (Ensuring the safe and sustainable development and application of nanotechnologies)
 Code Call H2020-NMBP-2016-two-stage
 Funding Scheme RIA
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2020-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY LU (ESCH SUR ALZETTE) coordinator 2˙395˙032.00
2    CARL ZEISS MICROSCOPY GMBH DE (Jena) participant 1˙200˙000.00
3    PHOTONIS NETHERLANDS BV NL (RODEN) participant 786˙250.00
4    HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV DE (DRESDEN) participant 593˙125.00
5    FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG DE (ERLANGEN) participant 587˙418.00
6    INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT FR (PARIS CEDEX 07) participant 449˙848.00
7    VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V. BE (MOL) participant 447˙925.00
8    MJR PHARMJET GMBH DE (UBERHERRM) participant 202˙000.00
9    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) participant 0.00

Map

 Project objective

The npSCOPE project aims at developing a new integrated instrument (the nanoparticle-scope) optimised for providing a complete physico-chemical characterisation of nanoparticles both in their pristine form or embedded in complex matrices such as biological tissues. Using sophisticated correlative data processing methodologies and algorithms based on statistical methods in conjunction with appropriate visualisation methods of the results, the npSCOPE instrument will allow rapid, accurate and reproducible measurements. The instrument will be based on the Gas Field Ion Source as a key enabling technology, which we will combine with a number of new developments in the field of electron and ion microscopy. We will progressively ramp up the TRL of the instrument and associated methodologies to reach TRL 7 by the end of the project. The new technology, and all related processes and methodologies, will be validated via round-robin studies performed independently by several partner institutions, crosschecked with conventional analysis technologies to demonstrate the advancements and capabilities of the npSCOPE technology and benchmarked in representative case studies. Given the low sample quantities needed and the strong potential of the instrument to generate high-quality physico-chemical data on nanomaterials, both ex situ and in situ, npSCOPE will allow a major step forward in defining key descriptors for read-across, grouping, in silico modelling and creating meaningful relationships with biological activity data for QSAR purposes. To reach these objectives, the project consortium will be composed of research centres internationally recognised for innovative instrument developments, well-established instrument manufacturers and experts in nanotoxicology in various fields of application to demonstrate and validate the applicability of npSCOPE for the risk assessment of nanomaterials in consumer products.

 Deliverables

List of deliverables.
Description of correlative workflow Documents, reports 2020-04-24 01:27:25
Description of cryo-workflow Documents, reports 2020-04-24 01:27:25
Confirmed specification Documents, reports 2020-04-24 01:27:25
Project website Websites, patent fillings, videos etc. 2020-04-24 01:27:25
Nano-material sampling and preparation protocols Documents, reports 2020-04-24 01:27:25

Take a look to the deliverables list in detail:  detailed list of npSCOPE deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Ionel Fizeșan, Sébastien Cambier, Elisa Moschini, Aline Chary, Inge Nelissen, Johanna Ziebel, Jean-Nicolas Audinot, Tom Wirtz, Marcin Kruszewski, Anca Pop, Béla Kiss, Tommaso Serchi, Felicia Loghin, Arno C. Gutleb
In vitro exposure of a 3D-tetraculture representative for the alveolar barrier at the air-liquid interface to silver particles and nanowires
published pages: , ISSN: 1743-8977, DOI: 10.1186/s12989-019-0297-1
Particle and Fibre Toxicology 16/1 2020-04-24
2019 Tom Wirtz, Olivier De Castro, Jean-Nicolas Audinot, Patrick Philipp
Imaging and Analytics on the Helium Ion Microscope
published pages: 523-543, ISSN: 1936-1327, DOI: 10.1146/annurev-anchem-061318-115457
Annual Review of Analytical Chemistry 12/1 2020-04-24

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The information about "NPSCOPE" are provided by the European Opendata Portal: CORDIS opendata.

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