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Opendata, web and dolomites

npSCOPE SIGNED

The nanoparticle-scope : a new integrated instrument for accurate and reproducible physico-chemical characterisation of nanoparticles (npSCOPE)

Total Cost €

EC-Contrib. €

Partnership

Views

Outcomes and
results

npSCOPE project word cloud

Explore the words cloud of the npSCOPE project. It provides you a very rough idea of what is the project "npSCOPE" about.

gas centres relationships validate accurate nanoparticles performed reproducible recognised quantities matrices independently descriptors manufacturers statistical situ internationally progressively microscopy risk advancements nanomaterials source scope rapid robin chemical round combine sophisticated qsar characterisation algorithms nanoparticle appropriate benchmarked visualisation experts biological ex physico conjunction conventional technologies nanotoxicology electron grouping read trl crosschecked ramp innovative complete data representative purposes generate correlative ion applicability pristine instrument form npscope tissues silico validated quality

Project "npSCOPE" data sheet

The following table provides information about the project.

Coordinator	LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY Organization address address: 5 AVENUE DES HAUTS FOURNEAUX city: ESCH SUR ALZETTE postcode: 4362 website: www.list.lu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Luxembourg [LU]
Project website	http://www.npscope.eu/
Total cost	7˙487˙475 €
EC max contribution	6˙661˙600 € (89%)
Programme	1. H2020-EU.2.1.2.2. (Ensuring the safe and sustainable development and application of nanotechnologies)
Code Call	H2020-NMBP-2016-two-stage
Funding Scheme	RIA
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2020-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY Organization address address: 5 AVENUE DES HAUTS FOURNEAUX city: ESCH SUR ALZETTE postcode: 4362 website: www.list.lu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	LU (ESCH SUR ALZETTE)	coordinator	2˙395˙032.00
2	CARL ZEISS MICROSCOPY GMBH CARL ZEISS MICROSCOPY GMBH Organization address address: Carl Zeiss Promenade 10 city: Jena postcode: 7745 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (Jena)	participant	1˙200˙000.00
3	PHOTONIS NETHERLANDS BV PHOTONIS NETHERLANDS BV Organization address address: DWAZZIEWEGEN 2 city: RODEN postcode: 9301 ZR website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (RODEN)	participant	786˙250.00
4	HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV Organization address address: BAUTZNER LANDSTRASSE 400 city: DRESDEN postcode: 1328 website: www.hzdr.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (DRESDEN)	participant	593˙125.00
5	FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG Organization address address: SCHLOSSPLATZ 4 city: ERLANGEN postcode: 91054 website: www.uni-erlangen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (ERLANGEN)	participant	587˙418.00
6	INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT Organization address address: Rue De L'Universite 147 city: PARIS CEDEX 07 postcode: 75338 website: www.inra.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS CEDEX 07)	participant	449˙848.00
7	VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V. VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V. Organization address address: BOERETANG 200 city: MOL postcode: 2400 website: www.vito.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (MOL)	participant	447˙925.00
8	MJR PHARMJET GMBH MJR PHARMJET GMBH Organization address address: INDUSTRIESTRASSE 1B city: UBERHERRM postcode: 66802 website: www.mjr-pharmjet.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (UBERHERRM)	participant	202˙000.00
9	EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Organization address address: Raemistrasse 101 city: ZUERICH postcode: 8092 website: https://www.ethz.ch/de.html contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (ZUERICH)	participant	0.00

Map

Project objective

The npSCOPE project aims at developing a new integrated instrument (the nanoparticle-scope) optimised for providing a complete physico-chemical characterisation of nanoparticles both in their pristine form or embedded in complex matrices such as biological tissues. Using sophisticated correlative data processing methodologies and algorithms based on statistical methods in conjunction with appropriate visualisation methods of the results, the npSCOPE instrument will allow rapid, accurate and reproducible measurements. The instrument will be based on the Gas Field Ion Source as a key enabling technology, which we will combine with a number of new developments in the field of electron and ion microscopy. We will progressively ramp up the TRL of the instrument and associated methodologies to reach TRL 7 by the end of the project. The new technology, and all related processes and methodologies, will be validated via round-robin studies performed independently by several partner institutions, crosschecked with conventional analysis technologies to demonstrate the advancements and capabilities of the npSCOPE technology and benchmarked in representative case studies. Given the low sample quantities needed and the strong potential of the instrument to generate high-quality physico-chemical data on nanomaterials, both ex situ and in situ, npSCOPE will allow a major step forward in defining key descriptors for read-across, grouping, in silico modelling and creating meaningful relationships with biological activity data for QSAR purposes. To reach these objectives, the project consortium will be composed of research centres internationally recognised for innovative instrument developments, well-established instrument manufacturers and experts in nanotoxicology in various fields of application to demonstrate and validate the applicability of npSCOPE for the risk assessment of nanomaterials in consumer products.

Deliverables

List of deliverables.
Description of correlative workflow	Documents, reports	2020-04-24 01:27:25
Description of cryo-workflow	Documents, reports	2020-04-24 01:27:25
Confirmed specification	Documents, reports	2020-04-24 01:27:25
Project website	Websites, patent fillings, videos etc.	2020-04-24 01:27:25
Nano-material sampling and preparation protocols	Documents, reports	2020-04-24 01:27:25

Take a look to the deliverables list in detail: detailed list of npSCOPE deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Ionel FizeÈ™an, SÃ©bastien Cambier, Elisa Moschini, Aline Chary, Inge Nelissen, Johanna Ziebel, Jean-Nicolas Audinot, Tom Wirtz, Marcin Kruszewski, Anca Pop, BÃ©la Kiss, Tommaso Serchi, Felicia Loghin, Arno C. Gutleb In vitro exposure of a 3D-tetraculture representative for the alveolar barrier at the air-liquid interface to silver particles and nanowires published pages: , ISSN: 1743-8977, DOI: 10.1186/s12989-019-0297-1	Particle and Fibre Toxicology 16/1	2020-04-24
2019	Tom Wirtz, Olivier De Castro, Jean-Nicolas Audinot, Patrick Philipp Imaging and Analytics on the Helium Ion Microscope published pages: 523-543, ISSN: 1936-1327, DOI: 10.1146/annurev-anchem-061318-115457	Annual Review of Analytical Chemistry 12/1	2020-04-24

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The information about "NPSCOPE" are provided by the European Opendata Portal: CORDIS opendata.

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