Opendata, web and dolomites

PATROLS SIGNED

Physiologically Anchored Tools for Realistic nanOmateriaL hazard aSsessment

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "PATROLS" data sheet

The following table provides information about the project.

Coordinator
SWANSEA UNIVERSITY 

Organization address
address: SINGLETON PARK
city: SWANSEA
postcode: SA2 8PP
website: www.swan.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 13˙108˙347 €
 EC max contribution 12˙714˙180 € (97%)
 Programme 1. H2020-EU.2.1.2.2. (Ensuring the safe and sustainable development and application of nanotechnologies)
 Code Call H2020-NMBP-2017-two-stage
 Funding Scheme /RIA
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2021-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SWANSEA UNIVERSITY UK (SWANSEA) coordinator 1˙436˙623.00
2    HERIOT-WATT UNIVERSITY UK (EDINBURGH) participant 1˙166˙363.00
3    DET NATIONALE FORSKNINGSCENTER FORARBEJDSMILJO DK (KOBENHAVN) participant 944˙616.00
4    RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU NL (BILTHOVEN) participant 931˙765.00
5    UNIVERSITE DE FRIBOURG CH (FRIBOURG) participant 863˙390.00
6    UNIVERSITEIT LEIDEN NL (LEIDEN) participant 850˙467.00
7    BASF SE DE (LUDWIGSHAFEN AM RHEIN) participant 759˙842.00
8    INSTITUT FUR UMWELTMEDIZINISCHE FORSCHUNG AN DER HEINRICH-HEINE-UNIVERSITAT DUSSELDORF GMBH DE (DUESSELDORF) participant 597˙252.00
9    THE UNIVERSITY OF EXETER UK (EXETER) participant 590˙886.00
10    DANMARKS TEKNISKE UNIVERSITET DK (KGS LYNGBY) participant 584˙987.00
11    UNIVERSITE DE NAMUR ASBL BE (NAMUR) participant 538˙712.00
12    INSPHERO AG CH (SCHLIEREN) participant 481˙961.00
13    CONSIGLIO NAZIONALE DELLE RICERCHE IT (ROMA) participant 441˙845.00
14    UNIVERSITE CATHOLIQUE DE LOUVAIN BE (LOUVAIN LA NEUVE) participant 428˙826.00
15    UNIVERSITA DI PISA IT (PISA) participant 384˙930.00
16    INSTITUTE OF OCCUPATIONAL MEDICINE UK (EDINBURGH) participant 370˙816.00
17    QSAR LAB SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA PL (GDANSK) participant 353˙193.00
18    MISVIK BIOLOGY OY FI (TURKU) participant 336˙325.00
19    EUROPEAN RESEARCH SERVICES GMBH DE (MUENSTER) participant 311˙250.00
20    NANOTECHNOLOGY INDUSTRIES ASSOCIATION BE (BRUXELLES) participant 251˙468.00
21    UNITED KINGDOM RESEARCH AND INNOVATION UK (SWINDON) participant 88˙656.00
22    HARVARD GLOBAL RESEARCH AND SUPPORT SERVICES INC. US (CAMBRIDGE) participant 0.00
23    KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE KR (DAEJEON) participant 0.00
24    MEDICAL RESEARCH COUNCIL UK (SWINDON) participant 0.00
25    UNIVERSITY OF SOUTH CAROLINA US (COLUMBIA) participant 0.00

Mappa

 Project objective

Nanotechnology promises significant scientific, economic and societal benefits, but commercialization and growth are threatened by safety uncertainties. Classical hazard testing strategies to define the human and environmental health impact of engineered nanomaterials (ENM) commonly apply unrealistic acute, high-doses to models that do not reflect the in vivo environment. Furthermore, existing in vitro and in silico hazard detection methods are not accurately predictive. PATROLS addresses these limitations by establishing and standardizing the next generation of advanced safety assessment tools for improved prediction of the adverse effects caused by chronic ENM exposure in human and environmental systems. PATROLS will deliver: 1) physiologically representative multi-cellular in vitro 3D lung, gastrointestinal tract and liver models; 2) cross-species models integrating human and environmental safety testing; 3) innovative ecotoxicity bioassays in several organisms across a food chain; 4) robust in silico models for dosimetry, interspecies toxicity extrapolation and hazard prediction. ENM characterization under physiologically relevant experimental conditions will be integral to this realistic, exposure driven strategy. A systems biology approach will also be adopted to identify key events linked to adverse outcome pathways, informing mechanism-based endpoints associated with real-life ENM exposures. These objectives will be achieved by an international network of world-leading academic, governmental, industrial, SME, risk assessment agency and NGO partners. The innovative in vitro and in silico nanosafety testing tools developed by PATROLS will balance speed, cost and biological complexity, while reducing uncertainty via improved predictive power. The smart targeted testing approach will drive a paradigm shift in (eco)toxicology towards mechanism-based ENM hazard assessment to support policy development in human and environmental nanosafety regulatory frameworks.

 Work performed, outcomes and results:  advancements report(s) 

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PATROLS" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PATROLS" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.2.1.2.2.)

PATROLS (2018)

Physiologically Anchored Tools for Realistic nanOmateriaL hazard aSsessment

Read More  

GRACIOUS (2018)

GRACIOUS: Grouping, Read-Across, CharacterIsation and classificatiOn framework for regUlatory risk assessment of manufactured nanomaterials and Safer design of nano-enabled products

Read More  

PROSAFE (2015)

Promoting the Implementation of Safe by Design

Read More