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GRACIOUS SIGNED

GRACIOUS: Grouping, Read-Across, CharacterIsation and classificatiOn framework for regUlatory risk assessment of manufactured nanomaterials and Safer design of nano-enabled products

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 GRACIOUS project word cloud

Explore the words cloud of the GRACIOUS project. It provides you a very rough idea of what is the project "GRACIOUS" about.

gracious    physicochemical    grouping    nm    regulatory    framework    read    actual    risk    nms    safety    health    industrial    environmental   

Project "GRACIOUS" data sheet

The following table provides information about the project.

Coordinator
HERIOT-WATT UNIVERSITY 

Organization address
address: Riccarton
city: EDINBURGH
postcode: EH14 4AS
website: www.hw.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 7˙180˙118 €
 EC max contribution 6˙999˙368 € (97%)
 Programme 1. H2020-EU.2.1.2.2. (Ensuring the safe and sustainable development and application of nanotechnologies)
 Code Call H2020-NMBP-2017-two-stage
 Funding Scheme /RIA
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2021-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HERIOT-WATT UNIVERSITY UK (EDINBURGH) coordinator 787˙325.00
2    BASF SE DE (LUDWIGSHAFEN AM RHEIN) participant 669˙618.00
3    RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU NL (BILTHOVEN) participant 522˙787.00
4    BUNDESINSTITUT FUER RISIKOBEWERTUNG DE (BERLIN) participant 466˙955.00
5    NATURAL ENVIRONMENT RESEARCH COUNCIL UK (SWINDON WILTSHIRE) participant 449˙787.00
6    DET NATIONALE FORSKNINGSCENTER FORARBEJDSMILJO DK (KOBENHAVN) participant 411˙162.00
7    ACONDICIONAMIENTO TARRASENSE ASSOCIACION ES (TERRASSA) participant 383˙287.00
8    GREENDECISION SRL IT (Venezia) participant 379˙375.00
9    INSTITUTE OF OCCUPATIONAL MEDICINE UK (EDINBURGH) participant 327˙475.00
10    JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION BE (BRUSSELS) participant 323˙947.00
11    UNIVERSITAT WIEN AT (WIEN) participant 309˙037.00
12    EUROPEAN RESEARCH SERVICES GMBH DE (MUENSTER) participant 301˙537.00
13    THE REACH CENTRE LIMITED UK (LONGRIDGE PRESTON) participant 249˙162.00
14    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) participant 217˙588.00
15    FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA IT (GENOVA) participant 217˙502.00
16    THINKWORKS BV NL (DELFT) participant 210˙537.00
17    IDEACONSULT LIMITED LIABILITY COMPANY BG (SOFIA) participant 205˙912.00
18    EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT CH (DUBENDORF) participant 173˙787.00
19    UNILEVER U.K. CENTRAL RESOURCES LIMITED UK (LONDON) participant 168˙568.00
20    ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFORIAS, TON EPIKOINONION KAI TIS GNOSIS EL (MAROUSSI) participant 124˙037.00
21    AKZO NOBEL PULP AND PERFORMANCE CHEMICALS AB SE (BOHUS) participant 99˙975.00
22    Arizona Board of Regents US (TEMPE) participant 0.00
23    DUKE UNIVERSITY US (DURHAM NC) participant 0.00

Mappa

 Project objective

Manufacturing and functionalising materials at the nanoscale leads to a whole array of nanomaterials (NMs) varying in e.g. size, morphology and surface characteristics. Apart from expected benefits, distinctive properties of NMs may also affect (environmental) health risks. Safety assessment requires sufficient information for each NM, but testing every unique NM for their potential adverse effects is virtually impossible. More efficient ways to obtain safety information are needed, which could be achieved by applying grouping and read-across approaches to NMs. On a conceptual level, regulatory accepted approaches for grouping and read-across for NMs already exist, but actual application remains difficult as the required knowledge is not systematically brought together, lacks data curation or is still missing. GRACIOUS will address this urgent need by developing a framework for grouping and read-across based on physicochemical, release, exposure, environmental fate, toxicokinetic and toxicological information. This framework will be delivered as a practical e-tool, fit-for-purpose for various key (regulatory and industrial) stakeholders, who will be engaged from the start of the project. To develop the framework, GRACIOUS will build upon currently available approaches by collating, curating and assimilating existing and new knowledge on intrinsic and extrinsic physicochemical properties in relation to their (environmental) health risk. The resulting framework will support safe innovation by enabling considerations of safety a.o. via grouping and read-across in industrial decision making at various stages of product development. For regulators and policy makers, GRACIOUS will facilitate actual application of grouping and read-across of NMs to enable risk analysis of NMs without extensive testing.

 Work performed, outcomes and results:  advancements report(s) 

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