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CCHFVaccine SIGNED

Crimean-Congo Haemorrhagic Fever Vaccine

Total Cost €

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EC-Contrib. €

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Partnership

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Project "CCHFVaccine" data sheet

The following table provides information about the project.

Coordinator
FOLKHALSOMYNDIGHETEN 

Organization address
address: NOBELS VAG 18
city: SOLNA
postcode: 171 82
website: http://folkhalsomyndigheten.se

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Project website http://www.cchfvaccine.eu/
 Total cost 6˙255˙909 €
 EC max contribution 5˙979˙607 € (96%)
 Programme 1. H2020-EU.3.1.2. (Preventing disease)
 Code Call H2020-SC1-2016-RTD
 Funding Scheme RIA
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2022-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FOLKHALSOMYNDIGHETEN SE (SOLNA) coordinator 1˙356˙000.00
2    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 2˙199˙576.00
3    FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT DE (GREIFSWALD-INSEL RIEMS) participant 505˙000.00
4    INSERM - TRANSFERT SA FR (PARIS) participant 351˙875.00
5    JUSTUS-LIEBIG-UNIVERSITAET GIESSEN DE (GIESSEN) participant 348˙281.00
6    Department of Health UK (Leeds) participant 348˙000.00
7    STATENS VETERINAERMEDICINSKA ANSTALT SE (UPPSALA) participant 240˙250.00
8    SIVAS CUMHURIYET UNIVERSITESI TR (SIVAS) participant 140˙250.00
9    BUNDESINSTITUT FUR IMPFSTOFFE UND BIOMEDIZINISCHE ARZNEIMITTEL DE (LANGEN) participant 136˙000.00
10    KAFKAS UNIVERSITESI TR (KARS) participant 134˙375.00
11    NATIONAL CENTER OF INFECTIOUS AND PARASITIC DISEASES BG (SOFIA) participant 80˙000.00
12    TAJIK RESEARCH INSTITUTE OF PREVENTIVE MEDICINE TJ (DUSHANBE) participant 80˙000.00
13    MINISTRIA E SHENDETESISE XK (PRISTINA) participant 60˙000.00

Map

 Project objective

Natural epidemics and outbreaks of emerging viral epidemics are growing problems internationally. The general aim of the CCHFVaccine project is to develop and deliver a vaccine, which can significantly increase our capacity to control the situation of Crimean Congo Haemorrhagic fever (CCHF) disease on a global basis. The proposed work program on CCHF virus aims to build a multidisciplinary research network, able to deliver vaccine candidates, methods and procedures eligible for clinical trials, with a special focus on prevention. Thanks to the background, unique facilities and tools available among the consortium participants, CCHFVaccine will deliver tools for countering the threat of this infection in Europe and endemic areas of the world. This work program will attempt to fill gaps in CCHFV virus research on immunology and vaccinology. To achieve this overall aim, an intensive work plan will be put in place with the following specific objectives: i) to produce vaccine candidates, ii) to bring several unique animal models into front line vaccine research, iii) to validate and bring the most promising vaccine candidates to clinical trials, iv) to ensure that an immune mediated protection is adequately understood, v) to perform clinical trials at Phase I and ensure a strategy for the effective deployment and utilization in resource-poor countries, and vi) to link this project to public health bodies, NGOs and vaccine companies. The proposed CCHFVaccine project will succeed in bringing together selected competitive advantages such as: operating capacity with appropriate facilities (state-of-the-art BSL-4s) and the only animal BSL-4 -with capacity to challenge domestic animals in Europe, highly experienced researchers in the development and evaluation of vaccine candidates, authorities and entities of human and animal health, clinical samples from endemic countries, and an international network proven to be functional by the previous EU-funded CCHFever and EDENext.

 Publications

year authors and title journal last update
List of publications.
2018 Jessica R. Spengler, Dennis A. Bente, Mike Bray, Felicity Burt, Roger Hewson, Gülay Korukluoglu, Ali Mirazimi, Friedemann Weber, Anna Papa
Second International Conference on Crimean-Congo Hemorrhagic Fever
published pages: 137-147, ISSN: 0166-3542, DOI: 10.1016/j.antiviral.2017.11.019
Antiviral Research 150 2020-03-11
2018 Amanda Fritzen, Christian Risinger, Gulay Korukluoglu, Iva Christova, Arina Corli Hitzeroth, Natalie Viljoen, Felicity Jane Burt, Ali Mirazimi, Ola Blixt
Epitope-mapping of the glycoprotein from Crimean-Congo hemorrhagic fever virus using a microarray approach
published pages: e0006598, ISSN: 1935-2735, DOI: 10.1371/journal.pntd.0006598
PLOS Neglected Tropical Diseases 12/7 2020-03-11
2017 Jorma Hinkula, Stéphanie Devignot, Sara Åkerström, Helen Karlberg, Eva Wattrang, Sándor Bereczky, Mehrdad Mousavi-Jazi, Christian Risinger, Gunnel Lindegren, Caroline Vernersson, Janusz Paweska, Petrus Jansen van Vuren, Ola Blixt, Alejandro Brun, Friedemann Weber, Ali Mirazimi
Immunization with DNA Plasmids Coding for Crimean-Congo Hemorrhagic Fever Virus Capsid and Envelope Proteins and/or Virus-Like Particles Induces Protection and Survival in Challenged Mice
published pages: , ISSN: 0022-538X, DOI: 10.1128/JVI.02076-16
Journal of Virology 91/10 2020-03-11

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The information about "CCHFVACCINE" are provided by the European Opendata Portal: CORDIS opendata.

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