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SpheroPredict

A 3D advanced test for prediction of drug response in secondary liver cancer

Total Cost €

0

EC-Contrib. €

0

Partnership

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 Outcomes and results

 SpheroPredict project word cloud

Explore the words cloud of the SpheroPredict project. It provides you a very rough idea of what is the project "SpheroPredict" about.

body    designed    economic    risked    death    regarding    proven    options    therapy    secondary    tumours    drug    treatment    migrating    incurred    locations    guidelines    3d    international    urgent    productivity    deathliest    inefficient    patient    alleviate    error    cancers    accurate    survival    entail    fail    published    efficacy    model    healthcare    line    time    de    metastatic    commercial    types    financial    tumour    dealing    innovative    personalised    causes    century    warrant    guideline    metastasizing    spherotec    heterogeneous    primary    cells    efficient    quality    first    installing    risk    platform    perspectives    toxicity    deaths    cancer    predict    individualised    lack    diseases    therapies    patients    cycle    micro    era    drugs    created    spheroid    life    solution    chemoresistance    commercialisation    chemotherapy    burden    liver    clear    worldwide    spheropredict    treatments    treat    medicine    feasibility    21st    trial    biologically   

Project "SpheroPredict" data sheet

The following table provides information about the project.

Coordinator		 SPHEROTEC GMBH 

Organization address
address: AM KLOPFERSPITZ 19
city: MARTINSRIED
postcode: 82152
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Germany [DE]
 Project website http://www.spherotec.com/ - www.spheromed.com - www.spheroselect.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2017-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SPHEROTEC GMBH DE (MARTINSRIED) coordinator 50˙000.00

Map

 Project objective

Cancer remains one of the deathliest diseases of the 21st century, with more than 1.9 M deaths per year in Europe. Some tumours entail a high risk of metastasizing, meaning that they are able to reach other locations in the body. Migrating cells from a primary tumour often cause secondary cancer in the liver, which is one of the leading causes of death worldwide.Regarding treatment options, international institutions have published clear guidelines about first line treatments to treat particular types of primary cancers. However, when dealing with secondary cancers (like metastatic liver cancer) there is a heterogeneous and very wide range of treatment options and no clear guidelines. The choice of treatment in secondary cancer is based in “trial and error”. This “trial and error” approach causes many patients fail to respond to therapy due to chemoresistance (lack of response to chemotherapy). In response, we at SpheroTec have created SpheroPredict, an individualised drug testing platform designed to predict the patient’s response to guideline therapies before installing the treatment cycle. Using cancer cells from the patient’s tumour, we build an accurate and biologically relevant 3D micro-tumour (spheroid) model to test the drugs and analyse the response in advance. In the end, only drugs with proven efficacy and low toxicity will be applied in the patient’s therapy cycle. In the era of personalised medicine and with the urgent need for de-risked and efficient drug treatments, we have developed an innovative solution that will greatly improve the patient’s survival time, quality of life and will help to alleviate the economic burden on the EU healthcare system incurred by inefficient therapies and productivity loss. Thus, in Phase 1, we aim to warrant the feasibility of the SpheroPredict project from the technical, commercial and financial perspectives, in order to ensure its success upon commercialisation.

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The information about "SPHEROPREDICT" are provided by the European Opendata Portal: CORDIS opendata.

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