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CoALIVE TERMINATED
Coenzyme A – Launch of In Vivo Experiments
Total Cost €
0EC-Contrib. €
0Partnership
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0CoALIVE project word cloud
Explore the words cloud of the CoALIVE project. It provides you a very rough idea of what is the project "CoALIVE" about.
suffering
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phosphopantetheine
fruit
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Project "CoALIVE" data sheet
The following table provides information about the project.
| Coordinator |
ACIES BIO BIOTEHNOLOSKE RAZISKAVE IN RAZVOJ DOO
Organization address contact info |
| Coordinator Country | Slovenia [SI] |
| Total cost | 74˙750 € |
| EC max contribution | 74˙750 € (100%) |
| Programme |
1. H2020-EU.2.3.2.2. (Enhancing the innovation capacity of SMEs) |
| Code Call | H2020-INNOSUP-02-2016 |
| Funding Scheme | CSA |
| Starting year | 2017 |
| Duration (year-month-day) | from 2017-09-29 to 2018-09-28 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | ACIES BIO BIOTEHNOLOSKE RAZISKAVE IN RAZVOJ DOO | SI (LJUBLJANA) | coordinator | 74˙750.00 |
Map
Project objective
Acies Bio is looking to hire an expert on disease model development – particularly whole organism models in fruit flies – to join our drug discovery team developing 4-phosphopantetheine-related compounds for treating a range of Coenzyme A (CoA) metabolism related pathologies. Acies Bio’s lead compound is able to directly manipulate cellular CoA levels, which addresses the common underlying cause of this class of diseases. High therapeutic potential of this innovative treatment has been demonstrated for pantothenate-kinase-associated neurodegeneration (PKAN) and has resulted in the European Medicines Agency granting our lead compound orphan medicinal product designation. Application of this class of compounds to related diseases forms a core part of our Innovation Strategy, and could have far reaching implications in diverse areas such as numerous rare metabolic diseases, Alzheimer's disease and diabetes. This would not only make treatment available to a wider population of patients, suffering from currently untreatable conditions, but also open new opportunities for Acies Bio. Despite being world leaders in the field of CoA metabolism, as evidenced by our contribution to the TIRCON consortium, prior recruitment of relevant expertise has been hindered by obstacles within the national labour market. Hence, this call affords a valuable opportunity to recruit an Innovation Associate, to evaluate existing models in fruit flies, develop new disease models, implement novel phenotypic assays, and lead a dedicated facility. Acies Bio will provide outstanding coordination and support facilities, state-of-the-art chemical synthesis and analytics laboratory and a research-driven, commercial environment. Successful completion of this crucial step for proof-of-concept in alternative metabolic diseases, will accelerate patent protection and market approval of these ground-breaking therapeutics.
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The information about "COALIVE" are provided by the European Opendata Portal: CORDIS opendata.
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No valid XML
lastchecktime (2024-04-19 12:54:57) correctly updated