Explore the words cloud of the DOC project. It provides you a very rough idea of what is the project "DOC" about.
The following table provides information about the project.
CARL VON OSSIETZKY UNIVERSITAET OLDENBURG
|Coordinator Country||Germany [DE]|
|Total cost||159˙460 €|
|EC max contribution||159˙460 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2017-04-01 to 2019-04-30|
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|1||CARL VON OSSIETZKY UNIVERSITAET OLDENBURG||DE (OLDENBURG)||coordinator||159˙460.00|
An ageing population as well as chronic and infectious diseases, pandemic threats and antimicrobial resistance are currently on the rise. As a consequence, increasing attention is paid to the development of novel drugs, treatments and personal care products. In this context, blue biotechnology offers an opportunity to explore the potential of the marine microbial world to produce biological active metabolites, which may support health and wellbeing. The general goal of this proposal is the extraction and identification of biologically active substances in one of the largest reservoirs of organic material on Earth: the recalcitrant marine dissolved organic matter (RDOM) pool. This pool is an unexplored potential source of bioactive substances. For this purpose, the RDOM will be extracted from (1) one of the oldest water masses of the global ocean located at intermediate depths of the North Pacific and (2) the reworked DOM of marine sediments porewater in the North Sea. A comparative screen will be performed with the more recent surface oceanic water of the North Pacific. The antioxidant, immunostimulant and antitumoral potential of these DOM samples will be explored to evaluate possible cosmetical and pharmaceutical suitability. The DOM molecular diversity and features identified by mass spectrometry and nuclear magnetic resonance will be correlated with the different modes of bioactivity. This proposal will enable Dr. Catalá to broaden her expertise on molecular characterization of the DOM pool, to learn new methodologies of bioactive substances identification as well as to meet future challenges on marine natural product research, endorsed by the H2020 Societal Challenges of 'Health, Demographic Change and Wellbeing' and 'Marine Research and the Bioeconomy'. This combination of expertise is unique, and thus will be a milestone in Dr. Catalá career towards an independent scientist of high international visibility.
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The information about "DOC" are provided by the European Opendata Portal: CORDIS opendata.
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