Opendata, web and dolomites

PRIMASKOTI

PReparing Introduction to MArket of SKOTI (PRIMASKOTI) - a breakthrough solution for real-time studies of cytoskeletal motors at single-molecule resolution

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 PRIMASKOTI project word cloud

Explore the words cloud of the PRIMASKOTI project. It provides you a very rough idea of what is the project "PRIMASKOTI" about.

throughput    neurodegeneration    engage    operate    minimize    tweezers    barriers    biomolecules    knife    modular    times    techniques    commercializing    stability    life    sciences    skoti    scope    flexibility    strengths    lower    imaging    surface    requirement    kits    commercialize    operation    solid    instruments    combines    resolution    scientific    simplify    force    requiring    division    service    commercially    transport    interactions    cell    edge    broaden    commercialization    swiss    experiments    microscopy    manipulation    molecule    cutting    contracts    ultra    cytoskeletal    mechanical    unprecedented    contact    pave    diseases    solution    molecular    single    ease    displacement    microscope    software    designed    preparation    environment    glass    instrument    tool    motor    probes    hardly    idea    machines    complete    platform    medical    cellular    primaskoti    cancer    optical    isolation    supplemented    automatization    motorization    difficult    prepare    specialized    protein   

Project "PRIMASKOTI" data sheet

The following table provides information about the project.

Coordinator
EBERHARD KARLS UNIVERSITAET TUEBINGEN 

Organization address
address: GESCHWISTER-SCHOLL-PLATZ
city: TUEBINGEN
postcode: 72074
website: www.uni-tuebingen.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 149˙238 €
 EC max contribution 149˙238 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-PoC
 Funding Scheme ERC-POC
 Starting year 2017
 Duration (year-month-day) from 2017-08-01   to  2019-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EBERHARD KARLS UNIVERSITAET TUEBINGEN DE (TUEBINGEN) coordinator 149˙238.00

Map

 Project objective

The PRIMASKOTI project will prepare the commercialization of SKOTI—the Swiss Knife for Optical Tweezers and Imaging. The scientific instrument SKOTI is designed to measure interactions between single biomolecules with a focus on cytoskeletal molecular machines. SKOTI combines several state-of-the-art microscopy techniques with contact-less mechanical manipulation, so-called optical tweezers. Because of its ultra high stability, SKOTI has its particular strengths in experiments requiring a solid support such as a glass surface. This requirement is often the case for cytoskeletal motor protein studies. Since these molecular machines are key to many essential cellular processes such as transport or cell division, being able to study their interactions is an important step towards understanding diseases such as cancer or neurodegeneration. However, due to the highly specialized knowledge necessary to build and operate such instruments, hardly commercially available, single-molecule experiments are difficult. By commercializing SKOTI, we aim to provide a simple-to-access tool which will broaden the scope of applications and users. SKOTI will provide a modular microscope and optical manipulation platform with unprecedented force- and displacement-resolution, ease of operation through motorization and automatization, flexibility, and overall stability of the system. The key idea is to commercialize a complete solution, where the instrument is supplemented with an isolation from the environment, operation and analysis software, specialized probes, service contracts, and kits for experiments that help to minimize preparation times. This approach will simplify single-molecule experiments, increase throughput, and lower barriers to engage in such studies. In the long term, our novel, cutting-edge research tool for life sciences will provide insight to essential cellular processes and pave the way for new medical approaches.

 Publications

year authors and title journal last update
List of publications.
2019 Gero L. Hermsdorf, Sven A. Szilagyi, Sebastian Rösch, Erik Schäffer
High performance passive vibration isolation system for optical tables using six-degree-of-freedom viscous damping combined with steel springs
published pages: 15113, ISSN: 0034-6748, DOI: 10.1063/1.5060707
Review of Scientific Instruments 90/1 2020-01-27

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PRIMASKOTI" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PRIMASKOTI" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

TRUST (2018)

Truth and Semantics

Read More  

LO-KMOF (2019)

Vapour-deposited metal-organic frameworks as high-performance gap-filling dielectrics for nanoelectronics

Read More  

PLAT_ACE (2019)

A new platform technology for the on-demand access to large acenes

Read More