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Photosynthetic energy balance, chloroplast integrity, carbon flow and epigenetic regulation of isoprenoid biosynthesis during leaf development and senescence

Total Cost €


EC-Contrib. €






 LEAF-OF-LIFE project word cloud

Explore the words cloud of the LEAF-OF-LIFE project. It provides you a very rough idea of what is the project "LEAF-OF-LIFE" about.

carotenoids    combining    basis    trajectories    cytokinins    poplar    exclusively    biosynthesis    plantation    natural    quantification    quantitative    photoprotective    methyl    spearheading    abscisic    thorough    leaves    plastome    almost    delay    species    relationships    isotope    predicting    regulation    regulatory    monitoring    plant    mep    trees    active    hydrocarbons    acid    crops    techniques    sequencing    supplied    class    genomics    versatile    energy    cascades    play    epigenomic    antioxidant    plantations    leaf    wheat    autumn    alter    phenology    crop    quantify    estimation    photosynthesis    youth    erythritol    mechanistic    chloroplast    stress    utilising    tracing    life    phosphate    tree    arabidopsis    intended    relationship    synthesizes    gene    volatile    integrity    epigenome    model    isoprenoids    stable    senescence    balance    analytical    deciduous    isoprenoid    discovery    global    models    hormone    pigments    carbon    age    demands    abiotic    span    time   

Project "LEAF-OF-LIFE" data sheet

The following table provides information about the project.


Organization address
city: ROMA
postcode: 185

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website
 Total cost 180˙277 €
 EC max contribution 180˙277 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-06-01   to  2019-05-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

The methyl erythritol phosphate (MEP) pathway in the chloroplast synthesizes isoprenoids (a class of hydrocarbons) by almost exclusively utilising carbon and energy supplied by photosynthesis in plant leaves. Volatile isoprenoids (antioxidant hydrocarbons), isoprenoid-type cytokinins (plant ‘youth’ hormone), carotenoids (photoprotective pigments), and abscisic acid (plant ‘stress’ hormone) are some of the active isoprenoid end-products of the MEP pathway that play a role in leaf senescence. We aim to quantify and model age-specific relationships between photosynthesis and MEP pathway during natural and abiotic-stress induced leaf senescence in three different plant systems: wheat (a crop), poplar (a plantation tree) and Arabidopsis (the model species for genomics). By combining leaf age-specific chloroplast energy balance estimation through photosynthesis modelling, quantification of carbon demands of isoprenoid biosynthesis using stable isotope tracing and advanced real-time analytical techniques, monitoring plastome and chloroplast integrity, and whole-epigenome sequencing, LEAF-OF-LIFE will (i) develop a versatile quantitative method for predicting leaf senescence trajectories based on the relationship between photosynthesis and isoprenoid biosynthesis during senescence and (ii) identify novel gene cascades involved in epigenomic regulation of the MEP pathway during natural and abiotic stress-induced leaf senescence. A thorough understanding of leaf age-specific changes in energy and carbon demands of isoprenoid biosynthesis will provide a strong mechanistic basis to phenology models of autumn senescence in deciduous trees. Discovery of novel gene regulatory cascades involved in age-specific changes in isoprenoid biosynthesis will be spearheading new research intended to target MEP pathway so as to alter leaf life span (delay stress-induced leaf senescence) in major global crops and plantations.


year authors and title journal last update
List of publications.
2019 Kaidala Ganesha Srikanta Dani, Ullasa Kodandaramaiah
Ageing in trees: Role of body size optimization in demographic senescence
published pages: 41-51, ISSN: 1433-8319, DOI: 10.1016/j.ppees.2018.10.002
Perspectives in Plant Ecology, Evolution and Systematics 36 2019-08-29

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